CRCGN017_MCF10A.WT.HP_24H:D05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description s26948 3.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAA1 acetyl-CoA acyltransferase 1 4.02328
ZNF586 zinc finger protein 586 3.68397
EAPP E2F-associated phosphoprotein 3.59789
SNAP25 synaptosomal-associated protein, 25kDa 3.53476
ZNF134 zinc finger protein 134 3.5027
CNRIP1 cannabinoid receptor interacting protein 1 3.37872
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.98605
BTK Bruton agammaglobulinemia tyrosine kinase 2.76472
SYNE2 spectrin repeat containing, nuclear envelope 2 2.7413
ABHD6 abhydrolase domain containing 6 2.68103
ZNF304 zinc finger protein 304 2.67555
WFS1 Wolfram syndrome 1 (wolframin) 2.64186
LOXL1 lysyl oxidase-like 1 2.56163
ZNF551 zinc finger protein 551 2.4065
EGLN1 egl-9 family hypoxia-inducible factor 1 2.30601
ADAM10 ADAM metallopeptidase domain 10 2.20704
WIF1 WNT inhibitory factor 1 2.14173
HLA-DRA major histocompatibility complex, class II, DR alpha 2.05002
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.04522

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -6.27031
DHRS7 dehydrogenase/reductase (SDR family) member 7 -6.07943
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.5135
CD320 CD320 molecule -3.01953
HMG20B high mobility group 20B -2.92138
TRAPPC3 trafficking protein particle complex 3 -2.90594
CDC25B cell division cycle 25B -2.50593
ARID4B AT rich interactive domain 4B (RBP1-like) -2.37361
CDX1 caudal type homeobox 1 -2.16426
HOXA5 homeobox A5 -2.14262
POLR1E polymerase (RNA) I polypeptide E, 53kDa -2.11
OXA1L oxidase (cytochrome c) assembly 1-like -2.01163