CRCGN017_MCF10A.WT.HP_24H:D07 Gene Set
Genes
56 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HOXA5
|
homeobox A5
|
7.58585
|
|
HBA1
|
hemoglobin, alpha 1
|
5.09888
|
|
HBB
|
hemoglobin, beta
|
4.74013
|
|
HMOX1
|
heme oxygenase 1
|
4.5675
|
|
PLS1
|
plastin 1
|
4.5578
|
|
TBX2
|
T-box 2
|
4.53073
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.3685
|
|
SMAD3
|
SMAD family member 3
|
3.65642
|
|
CLNS1A
|
chloride channel, nucleotide-sensitive, 1A
|
3.46815
|
|
FHL2
|
four and a half LIM domains 2
|
3.3989
|
|
PKN1
|
protein kinase N1
|
3.03982
|
|
BAG3
|
BCL2-associated athanogene 3
|
2.9869
|
|
TCEA2
|
transcription elongation factor A (SII), 2
|
2.9539
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.89198
|
|
EFHD2
|
EF-hand domain family, member D2
|
2.84055
|
|
RSF1
|
remodeling and spacing factor 1
|
2.7998
|
|
WIF1
|
WNT inhibitory factor 1
|
2.7514
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.6588
|
|
NARS2
|
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
|
2.55385
|
|
TBPL1
|
TBP-like 1
|
2.4531
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
2.26677
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.23155
|
|
SLC35F2
|
solute carrier family 35, member F2
|
2.19755
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.1724
|
|
DSG2
|
desmoglein 2
|
2.13225
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.0938
|
|
AKAP10
|
A kinase (PRKA) anchor protein 10
|
2.09125
|
|
THAP12
|
THAP domain containing 12
|
2.08775
|
|
CASK
|
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
|
2.085
|
|
HOXA4
|
homeobox A4
|
2.0597
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.04995
|
|
CDC7
|
cell division cycle 7
|
2.0146
|
|
STX1A
|
syntaxin 1A (brain)
|
2.01215
|
|
KCTD3
|
potassium channel tetramerization domain containing 3
|
2.0084
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KRT14
|
keratin 14, type I
|
-5.5079
|
|
CYCS
|
cytochrome c, somatic
|
-5.26145
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-5.1042
|
|
CD58
|
CD58 molecule
|
-4.9025
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-4.03885
|
|
S100A4
|
S100 calcium binding protein A4
|
-2.87875
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.8072
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.6259
|
|
RBM34
|
RNA binding motif protein 34
|
-2.4774
|
|
FKBP9
|
FK506 binding protein 9, 63 kDa
|
-2.4424
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
-2.40543
|
|
GSDME
|
gasdermin E
|
-2.294
|
|
SLC26A2
|
solute carrier family 26 (anion exchanger), member 2
|
-2.27435
|
|
NDUFA6
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
|
-2.20248
|
|
GUK1
|
guanylate kinase 1
|
-2.1878
|
|
NISCH
|
nischarin
|
-2.16565
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-2.13385
|
|
PFN1
|
profilin 1
|
-2.12935
|
|
GGPS1
|
geranylgeranyl diphosphate synthase 1
|
-2.0894
|
|
PRODH
|
proline dehydrogenase (oxidase) 1
|
-2.0715
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
-2.0667
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.0044
|
