| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tretinoin 3.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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70 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HOXA5 | homeobox A5 | 6.47765 |
| MAMLD1 | mastermind-like domain containing 1 | 4.8781 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.8676 |
| TCEA2 | transcription elongation factor A (SII), 2 | 3.7212 |
| HBB | hemoglobin, beta | 3.47373 |
| BAG3 | BCL2-associated athanogene 3 | 3.3645 |
| FHL2 | four and a half LIM domains 2 | 3.2862 |
| NOSIP | nitric oxide synthase interacting protein | 2.97755 |
| PLS1 | plastin 1 | 2.95985 |
| HBA1 | hemoglobin, alpha 1 | 2.94635 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 2.70215 |
| CCDC59 | coiled-coil domain containing 59 | 2.56275 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.5187 |
| TSPAN6 | tetraspanin 6 | 2.4925 |
| MICALL1 | MICAL-like 1 | 2.3803 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.32475 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.32465 |
| NRIP1 | nuclear receptor interacting protein 1 | 2.31737 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.27965 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.25675 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | 2.22787 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 2.22073 |
| TSC22D1 | TSC22 domain family, member 1 | 2.1823 |
| HOXA1 | homeobox A1 | 2.1706 |
| STAMBP | STAM binding protein | 2.1255 |
| PLAT | plasminogen activator, tissue | 2.12265 |
| PLSCR1 | phospholipid scramblase 1 | 2.1053 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 | 2.10295 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.1027 |
| ITK | IL2-inducible T-cell kinase | 2.0696 |
| IL1B | interleukin 1, beta | 2.06052 |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 2.01575 |
| MPHOSPH6 | M-phase phosphoprotein 6 | 2.00175 |
| Symbol | Name | Standardized Value |
|---|---|---|
| S100A8 | S100 calcium binding protein A8 | -5.0 |
| NUP85 | nucleoporin 85kDa | -4.8257 |
| PCNA | proliferating cell nuclear antigen | -4.81085 |
| YME1L1 | YME1-like 1 ATPase | -4.74125 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -3.5209 |
| CDR2L | cerebellar degeneration-related protein 2-like | -3.46635 |
| TMEM94 | transmembrane protein 94 | -3.34935 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -3.14003 |
| SLC38A12 | solute carrier family 38 member 12 | -2.7152 |
| CASKIN2 | CASK interacting protein 2 | -2.57233 |
| ATG3 | autophagy related 3 | -2.52185 |
| FDXR | ferredoxin reductase | -2.50095 |
| GRB2 | growth factor receptor-bound protein 2 | -2.46515 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | -2.4592 |
| ABI1 | abl-interactor 1 | -2.4558 |
| S100A4 | S100 calcium binding protein A4 | -2.43555 |
| SAP30BP | SAP30 binding protein | -2.4305 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.3327 |
| FAT1 | FAT atypical cadherin 1 | -2.26225 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | -2.25643 |
| CYBC1 | cytochrome b-245 chaperone 1 | -2.19045 |
| MEGF8 | multiple EGF-like-domains 8 | -2.17865 |
| TMEM80 | transmembrane protein 80 | -2.16447 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -2.13065 |
| COXFA4L2 | cytochrome c oxidase hypoxia associated subunit FA4L2 | -2.11325 |
| SUMO4 | small ubiquitin-like modifier 4 | -2.09925 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C | -2.0945 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase | -2.0905 |
| EXPH5 | exophilin 5 | -2.05687 |
| HDAC5 | histone deacetylase 5 | -2.04825 |
| MAVS | mitochondrial antiviral signaling protein | -2.0474 |
| CTC1 | CTS telomere maintenance complex component 1 | -2.0464 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.04065 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -2.0319 |
| ELOVL4 | ELOVL fatty acid elongase 4 | -2.02095 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.0123 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -2.0085 |