| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | lg100754 1.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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72 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 5.09706 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.9706 |
| HOXA5 | homeobox A5 | 4.5159 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 4.18907 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.79785 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.53835 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.06897 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 2.9476 |
| RBBP5 | retinoblastoma binding protein 5 | 2.92645 |
| MTA2 | metastasis associated 1 family, member 2 | 2.8865 |
| PMM1 | phosphomannomutase 1 | 2.63945 |
| GSTK1 | glutathione S-transferase kappa 1 | 2.53145 |
| LY75-CD302 | LY75-CD302 readthrough | 2.41805 |
| HOXB7 | homeobox B7 | 2.40382 |
| ADRB2 | adrenoceptor beta 2, surface | 2.39785 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 2.36545 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 2.34271 |
| SDR39U1 | short chain dehydrogenase/reductase family 39U, member 1 | 2.34065 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 2.32035 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.28717 |
| HOXA4 | homeobox A4 | 2.24275 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 2.23585 |
| LOC122539214 | Zinc finger protein LOC122539214 | 2.2054 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 2.18095 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.1796 |
| MSX1 | msh homeobox 1 | 2.1781 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 2.1633 |
| NRIP1 | nuclear receptor interacting protein 1 | 2.1063 |
| SPATA5L1 | spermatogenesis associated 5-like 1 | 2.106 |
| TBCCD1 | TBCC domain containing 1 | 2.10085 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.0693 |
| PRPF39 | pre-mRNA processing factor 39 | 2.0539 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 | 2.05375 |
| CALML4 | calmodulin-like 4 | 2.04035 |
| NUTF2 | nuclear transport factor 2 | 2.02315 |
| ABHD10 | abhydrolase domain containing 10 | 2.0122 |
| ZNF292 | zinc finger protein 292 | 2.00428 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MSMO1 | methylsterol monooxygenase 1 | -5.70925 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -5.69777 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.21215 |
| TXNDC9 | thioredoxin domain containing 9 | -4.9348 |
| DNM1L | dynamin 1-like | -4.891 |
| CCNB1 | cyclin B1 | -4.5342 |
| YME1L1 | YME1-like 1 ATPase | -4.15352 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.149 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.7134 |
| MTPAP | mitochondrial poly(A) polymerase | -3.5771 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -3.19737 |
| SQLE | squalene epoxidase | -2.87717 |
| TXNL1 | thioredoxin-like 1 | -2.77675 |
| FADS2 | fatty acid desaturase 2 | -2.73935 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -2.70205 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -2.5985 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -2.4856 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | -2.3863 |
| ABI1 | abl-interactor 1 | -2.3411 |
| UBFD1 | ubiquitin family domain containing 1 | -2.25235 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 | -2.21385 |
| TLCD3A | TLC domain containing 3A | -2.20935 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) | -2.1636 |
| NME7 | NME/NM23 family member 7 | -2.13745 |
| MVD | mevalonate (diphospho) decarboxylase | -2.1311 |
| RAB32 | RAB32, member RAS oncogene family | -2.12895 |
| LHX1 | LIM homeobox 1 | -2.12665 |
| NDUFS2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | -2.12005 |
| SERGEF | secretion regulating guanine nucleotide exchange factor | -2.10265 |
| PITPNA | phosphatidylinositol transfer protein, alpha | -2.05072 |
| CCDC169-SOHLH2 | CCDC169-SOHLH2 readthrough | -2.0448 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 | -2.04362 |
| WAC | WW domain containing adaptor with coiled-coil | -2.00633 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 | -2.00485 |
| GMPS | guanine monphosphate synthase | -2.00245 |
