CRCGN017_MCF10A.WT.HP_24H:D11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description lg100754 0.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NANOS3 nanos homolog 3 (Drosophila) 5.0
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.8194
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.6319
HOXA5 homeobox A5 4.6048
ACAA1 acetyl-CoA acyltransferase 1 3.24353
IGHMBP2 immunoglobulin mu binding protein 2 2.9704
ADRB2 adrenoceptor beta 2, surface 2.8586
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.24985
UBP1 upstream binding protein 1 (LBP-1a) 2.00615

decreased expression

Symbol Name Standardized Value
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.4797
DERA deoxyribose-phosphate aldolase (putative) -5.1186
TSPAN4 tetraspanin 4 -4.77085
YME1L1 YME1-like 1 ATPase -4.44272
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.5841
KRT14 keratin 14, type I -3.1367
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.00093
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -2.93695
FPGS folylpolyglutamate synthase -2.76205
WASHC4 WASH complex subunit 4 -2.56248
XPO7 exportin 7 -2.3125
AMOTL2 angiomotin like 2 -2.05095
WAC WW domain containing adaptor with coiled-coil -2.04165
ABI1 abl-interactor 1 -2.0124