CRCGN017_MCF10A.WT.HP_24H:D12 Gene Set
Genes
29 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INTS3
|
integrator complex subunit 3
|
5.04755
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
4.5902
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
4.4964
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
4.14045
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
4.08825
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.89447
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.38115
|
|
DNAJB1
|
DnaJ (Hsp40) homolog, subfamily B, member 1
|
2.77778
|
|
ELAVL1
|
ELAV like RNA binding protein 1
|
2.5752
|
|
HOXA5
|
homeobox A5
|
2.53585
|
|
HBB
|
hemoglobin, beta
|
2.53143
|
|
NDUFA7
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
|
2.4981
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.28805
|
|
BGLAP
|
bone gamma-carboxyglutamate (gla) protein
|
2.1817
|
|
WIF1
|
WNT inhibitory factor 1
|
2.083
|
|
FBXO11
|
F-box protein 11
|
2.07163
|
|
CEBPG
|
CCAAT/enhancer binding protein (C/EBP), gamma
|
2.0163
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VDAC1
|
voltage-dependent anion channel 1
|
-4.08143
|
|
LYPLA1
|
lysophospholipase I
|
-3.7095
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.56905
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.56575
|
|
MT2A
|
metallothionein 2A
|
-3.33335
|
|
WASHC4
|
WASH complex subunit 4
|
-2.81562
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.7432
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
-2.6213
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
-2.55692
|
|
ATP6V1H
|
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
|
-2.251
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
-2.15807
|
|
KRT14
|
keratin 14, type I
|
-2.0791
|
