CRCGN017_MCF10A.WT.HP_24H:D13 Gene Set
Genes
34 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
5.2862
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.17335
|
|
SLC37A4
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
4.7636
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
4.7386
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.23675
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
2.56205
|
|
MAP2K5
|
mitogen-activated protein kinase kinase 5
|
2.36703
|
|
DVL3
|
dishevelled segment polarity protein 3
|
2.2232
|
|
ZNF672
|
zinc finger protein 672
|
2.1875
|
|
HMGA2
|
high mobility group AT-hook 2
|
2.152
|
|
GALNT12
|
polypeptide N-acetylgalactosaminyltransferase 12
|
2.12735
|
|
IVNS1ABP
|
influenza virus NS1A binding protein
|
2.09902
|
|
ACIN1
|
apoptotic chromatin condensation inducer 1
|
2.0537
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.3769
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-5.03785
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-5.03067
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
-4.6238
|
|
KRT14
|
keratin 14, type I
|
-4.2341
|
|
TKT
|
transketolase
|
-3.3688
|
|
PSMD4
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
|
-3.28853
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.6095
|
|
RRAGC
|
Ras-related GTP binding C
|
-2.4728
|
|
TMEM127
|
transmembrane protein 127
|
-2.37705
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
-2.35428
|
|
PSMB4
|
proteasome (prosome, macropain) subunit, beta type, 4
|
-2.3042
|
|
CBFA2T3
|
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
|
-2.21845
|
|
RNF25
|
ring finger protein 25
|
-2.19055
|
|
COX5B
|
cytochrome c oxidase subunit Vb
|
-2.12895
|
|
PTK7
|
protein tyrosine kinase 7 (inactive)
|
-2.06825
|
|
MMADHC
|
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
|
-2.052
|
|
CYTH2
|
cytohesin 2
|
-2.052
|
|
SMPDL3B
|
sphingomyelin phosphodiesterase, acid-like 3B
|
-2.0515
|
|
SLC67A2
|
solute carrier family 67 member 2
|
-2.01993
|
|
SPCS2
|
signal peptidase complex subunit 2 homolog (S. cerevisiae)
|
-2.01032
|
