CRCGN017_MCF10A.WT.HP_24H:D15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description galangin with tcdd perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

41 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 5.01101
HBB hemoglobin, beta 4.91292
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.73378
SPAG4 sperm associated antigen 4 4.589
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.53495
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 4.419
TPD52L2 tumor protein D52-like 2 3.62805
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 3.50623
KDM5D lysine (K)-specific demethylase 5D 3.21665
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 3.11245
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.90295
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 2.5258
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.52245
ECD ecdysoneless homolog (Drosophila) 2.33345
TMEM186 transmembrane protein 186 2.2762
KLHL21 kelch-like family member 21 2.2463
DSCC1 DNA replication and sister chromatid cohesion 1 2.19715
USP9Y ubiquitin specific peptidase 9, Y-linked 2.1543
WIF1 WNT inhibitory factor 1 2.0786
ERI2 ERI1 exoribonuclease family member 2 2.0419
NMU neuromedin U 2.02785

decreased expression

Symbol Name Standardized Value
COG2 component of oligomeric golgi complex 2 -5.32875
TSPAN4 tetraspanin 4 -4.54807
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.97992
SMC1A structural maintenance of chromosomes 1A -3.02342
IGFBP7 insulin-like growth factor binding protein 7 -2.95037
STK25 serine/threonine kinase 25 -2.8095
KDM5C lysine (K)-specific demethylase 5C -2.48155
WASHC4 WASH complex subunit 4 -2.45075
SMNDC1 survival motor neuron domain containing 1 -2.43555
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.29295
RHOF ras homolog family member F (in filopodia) -2.27765
DUSP4 dual specificity phosphatase 4 -2.19103
FOXN2 forkhead box N2 -2.1507
UBA1 ubiquitin-like modifier activating enzyme 1 -2.09235
BASP1 brain abundant, membrane attached signal protein 1 -2.07245
TKT transketolase -2.04227
IFT88 intraflagellar transport 88 -2.03375
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.03275
PUDP pseudouridine 5'-phosphatase -2.0267
ZNF516 zinc finger protein 516 -2.00685