CRCGN017_MCF10A.WT.HP_24H:D16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description chlorpropamide 100.46 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 5.0
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.19005
PEX11A peroxisomal biogenesis factor 11 alpha 4.0371
EPHB2 EPH receptor B2 3.90389
HBB hemoglobin, beta 3.37858
ADRB2 adrenoceptor beta 2, surface 2.4703
ZBTB35 zinc finger and BTB domain containing 35 2.3915
CCNA1 cyclin A1 2.34445
CCNF cyclin F 2.31533
TRIP10 thyroid hormone receptor interactor 10 2.29295
HBA1 hemoglobin, alpha 1 2.22093
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.08358
PYCR1 pyrroline-5-carboxylate reductase 1 2.0533
TYK2 tyrosine kinase 2 2.04055

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -5.0245
OXA1L oxidase (cytochrome c) assembly 1-like -5.0
CCDC86 coiled-coil domain containing 86 -4.8591
ETFB electron-transfer-flavoprotein, beta polypeptide -3.9362
NT5DC2 5'-nucleotidase domain containing 2 -3.6141
KRT14 keratin 14, type I -3.16065
DDB1 damage-specific DNA binding protein 1, 127kDa -2.2382
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.1521