CRCGN017_MCF10A.WT.HP_24H:D19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-aminofluorene 99.15 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 10.0
COMP cartilage oligomeric matrix protein 3.4833
HBB hemoglobin, beta 3.1894
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.8288
HBA1 hemoglobin, alpha 1 2.73724
CEMIP2 cell migration inducing hyaluronidase 2 2.61355
KDM5B lysine (K)-specific demethylase 5B 2.39777
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.33318
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.21105
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.16319
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.0226

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -5.32205
TUBB6 tubulin, beta 6 class V -5.16335
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.70865
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.4312
CD44 CD44 molecule (Indian blood group) -4.20183
KIF20A kinesin family member 20A -4.1636
ERC2 ELKS/RAB6-interacting/CAST family member 2 -3.46355
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.70708
CREG1 cellular repressor of E1A-stimulated genes 1 -2.3272
GRHL2 grainyhead-like 2 (Drosophila) -2.2437
REG1B regenerating islet-derived 1 beta -2.1613
CDH15 cadherin 15, type 1, M-cadherin (myotubule) -2.12483
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -2.1171
BPHL biphenyl hydrolase-like (serine hydrolase) -2.0858