CRCGN017_MCF10A.WT.HP_24H:D23 Gene Set
Genes
34 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.44785
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
5.1554
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.76195
|
|
WIF1
|
WNT inhibitory factor 1
|
4.7142
|
|
RBKS
|
ribokinase
|
2.86593
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.63645
|
|
RBMX
|
RNA binding motif protein, X-linked
|
2.58825
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.57818
|
|
CDK7
|
cyclin-dependent kinase 7
|
2.56675
|
|
C1QB
|
complement component 1, q subcomponent, B chain
|
2.3662
|
|
HSD17B7
|
hydroxysteroid (17-beta) dehydrogenase 7
|
2.33265
|
|
FBXO11
|
F-box protein 11
|
2.31712
|
|
MMP1
|
matrix metallopeptidase 1
|
2.19975
|
|
CRIPT
|
cysteine-rich PDZ-binding protein
|
2.17895
|
|
AP5M1
|
adaptor-related protein complex 5, mu 1 subunit
|
2.16275
|
|
GNA14
|
guanine nucleotide binding protein (G protein), alpha 14
|
2.1458
|
|
TMEM135
|
transmembrane protein 135
|
2.098
|
|
NPY1R
|
neuropeptide Y receptor Y1
|
2.0929
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.0867
|
|
CSNK1A1
|
casein kinase 1, alpha 1
|
2.01292
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HAT1
|
histone acetyltransferase 1
|
-5.6634
|
|
TUBB6
|
tubulin, beta 6 class V
|
-5.27705
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.88255
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-4.75955
|
|
SCRIB
|
scribbled planar cell polarity protein
|
-3.186
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
-2.95165
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.89182
|
|
SNRPD3
|
small nuclear ribonucleoprotein D3 polypeptide 18kDa
|
-2.3007
|
|
MRTO4
|
mRNA turnover 4 homolog (S. cerevisiae)
|
-2.29265
|
|
SMPD4
|
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
|
-2.27655
|
|
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
-2.2748
|
|
NOP14
|
NOP14 nucleolar protein
|
-2.13935
|
|
SLC52A2
|
solute carrier family 52 (riboflavin transporter), member 2
|
-2.03498
|
|
EYA2
|
EYA transcriptional coactivator and phosphatase 2
|
-2.0255
|
