CRCGN017_MCF10A.WT.HP_24H:D24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3'-dimethoxybenzidine.2hcl 10.7 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:D24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 4.66105
CNRIP1 cannabinoid receptor interacting protein 1 3.45235
SESN1 sestrin 1 3.33415
ACAA1 acetyl-CoA acyltransferase 1 3.16455
USP6NL USP6 N-terminal like 2.88765
STK10 serine/threonine kinase 10 2.44618
ZBTB35 zinc finger and BTB domain containing 35 2.28715
HAMP hepcidin antimicrobial peptide 2.1549
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.14095
AGR2 anterior gradient 2 2.0127

decreased expression

Symbol Name Standardized Value
TNIP1 TNFAIP3 interacting protein 1 -4.95235
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.9252
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.5137
S100A8 S100 calcium binding protein A8 -3.6807
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -3.23835
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -3.2173
TLCD3A TLC domain containing 3A -3.2127
XPO7 exportin 7 -3.0472
GDF15 growth differentiation factor 15 -2.91675
FKBP4 FK506 binding protein 4, 59kDa -2.6102
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -2.42185
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.3724
PFN1 profilin 1 -2.32735
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.30173
WNT5A wingless-type MMTV integration site family, member 5A -2.27367
EIF3G eukaryotic translation initiation factor 3, subunit G -2.1146
SH2D4A SH2 domain containing 4A -2.0816
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.0611
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.05905
EIF3D eukaryotic translation initiation factor 3, subunit D -2.00185