CRCGN017_MCF10A.WT.HP_24H:E07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description rotenone 101.98 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

1083 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:E07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL2 chemokine (C-X-C motif) ligand 2 7.57265
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 6.6407
UBQLN2 ubiquilin 2 5.8373
KCTD5 potassium channel tetramerization domain containing 5 5.4524
E2F2 E2F transcription factor 2 4.80835
ZW10 zw10 kinetochore protein 4.74715
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 4.6363
TP53BP2 tumor protein p53 binding protein 2 4.56335
STIMATE STIM activating enhancer 4.44875
ADGRE5 adhesion G protein-coupled receptor E5 4.30455
MYH9 myosin, heavy chain 9, non-muscle 4.2787
OXSR1 oxidative stress responsive 1 4.17515
PLS1 plastin 1 4.12805
TGFA transforming growth factor, alpha 4.09938
AFF4 AF4/FMR2 family, member 4 4.02765
CCL20 chemokine (C-C motif) ligand 20 3.9059
TNIP1 TNFAIP3 interacting protein 1 3.8638
H2BC9 H2B clustered histone 9 3.79235
IGHMBP2 immunoglobulin mu binding protein 2 3.7806
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.75345
CDCP1 CUB domain containing protein 1 3.7461
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 3.74215
PLEK2 pleckstrin 2 3.6501
SQOR sulfide quinone oxidoreductase 3.5999
CAB39 calcium binding protein 39 3.55935
DUSP14 dual specificity phosphatase 14 3.51845
RGS2 regulator of G-protein signaling 2 3.4956
STXBP1 syntaxin binding protein 1 3.46445
LAMB3 laminin, beta 3 3.45405
RTN4 reticulon 4 3.43253
DUSP7 dual specificity phosphatase 7 3.41318
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 3.41265
MYL9 myosin, light chain 9, regulatory 3.4097
KLF1 Kruppel-like factor 1 (erythroid) 3.4044
MCC mutated in colorectal cancers 3.39495
MSRA methionine sulfoxide reductase A 3.3616
SH2B3 SH2B adaptor protein 3 3.29375
IL1B interleukin 1, beta 3.29285
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.2856
LRRC42 leucine rich repeat containing 42 3.28155
TPST2 tyrosylprotein sulfotransferase 2 3.27665
PLAU plasminogen activator, urokinase 3.24643
WDR45B WD repeat domain 45B 3.24355
LOC122526780 uncharacterized LOC122526780 3.2356
SPAG4 sperm associated antigen 4 3.2276
PTPN1 protein tyrosine phosphatase, non-receptor type 1 3.21495
NT5E 5'-nucleotidase, ecto (CD73) 3.1963
KANSL3 KAT8 regulatory NSL complex subunit 3 3.1785
H2BC12 H2B clustered histone 12 3.17815
BDKRB2 bradykinin receptor B2 3.1726
GYPB glycophorin B (MNS blood group) 3.17175
LIMS2 LIM and senescent cell antigen-like domains 2 3.16195
IL15RA interleukin 15 receptor, alpha 3.1594
CKB creatine kinase, brain 3.15885
ITGAV integrin, alpha V 3.15765
TMBIM1 transmembrane BAX inhibitor motif containing 1 3.15425
MIDEAS mitotic deacetylase associated SANT domain protein 3.1529
NPC1 Niemann-Pick disease, type C1 3.12602
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.11785
RBM6 RNA binding motif protein 6 3.117
ALAS2 5'-aminolevulinate synthase 2 3.10195
TENT4A terminal nucleotidyltransferase 4A 3.0586
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 3.0581
MMP1 matrix metallopeptidase 1 3.0515
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 3.0493
CTLA4 cytotoxic T-lymphocyte-associated protein 4 3.0448
RHCE Rh blood group, CcEe antigens 3.04152
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 3.0365
PZP pregnancy-zone protein 3.01585
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 3.0069
STX4 syntaxin 4 2.99955
H2BC4 H2B clustered histone 4 2.96523
OCRL oculocerebrorenal syndrome of Lowe 2.95785
TSPO2 translocator protein 2 2.95645
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 2.95565
CXCL3 chemokine (C-X-C motif) ligand 3 2.9516
EHD1 EH-domain containing 1 2.94258
ARL14 ADP-ribosylation factor-like 14 2.94085
GLIPR1 GLI pathogenesis-related 1 2.92605
DUSP4 dual specificity phosphatase 4 2.91578
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 2.91512
NOCT nocturnin 2.9114
STK10 serine/threonine kinase 10 2.90847
IRF6 interferon regulatory factor 6 2.9045
TICAM1 toll-like receptor adaptor molecule 1 2.8975
CHIC2 cysteine-rich hydrophobic domain 2 2.89615
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 2.8922
ELOVL1 ELOVL fatty acid elongase 1 2.87507
RNF19B ring finger protein 19B 2.86497
TOR4A torsin family 4, member A 2.86315
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.8564
LUZP2 leucine zipper protein 2 2.8508
XK X-linked Kx blood group 2.8441
GRAMD2B GRAM domain containing 2B 2.84405
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.8419
CNIH4 cornichon family AMPA receptor auxiliary protein 4 2.83715
TXNRD1 thioredoxin reductase 1 2.83485
TAL1 T-cell acute lymphocytic leukemia 1 2.83092
H2AC19 H2A clustered histone 19 2.82868
CCNP cyclin P 2.82855
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 2.8132
IL1A interleukin 1, alpha 2.8094
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.8054
AIDA axin interactor, dorsalization associated 2.8036
SYNGAP1 synaptic Ras GTPase activating protein 1 2.80235
LNPEP leucyl/cystinyl aminopeptidase 2.80095
HHLA1 HERV-H LTR-associating 1 2.798
CCL15 chemokine (C-C motif) ligand 15 2.79145
COL4A5 collagen, type IV, alpha 5 2.77785
GID4 GID complex subunit 4 2.76905
AGPS alkylglycerone phosphate synthase 2.7655
PLA2G1B phospholipase A2, group IB (pancreas) 2.7643
TCL1A T-cell leukemia/lymphoma 1A 2.74845
SQLE squalene epoxidase 2.7412
GARS1 glycyl-tRNA synthetase 1 2.73995
H1-2 H1.2 linker histone, cluster member 2.7256
PVR poliovirus receptor 2.72447
KLF7 Kruppel-like factor 7 (ubiquitous) 2.72185
WASHC5 WASH complex subunit 5 2.7217
METRN meteorin, glial cell differentiation regulator 2.719
PRSS3 protease, serine, 3 2.71808
CSRP1 cysteine and glycine-rich protein 1 2.71688
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 2.69935
MARK4 MAP/microtubule affinity-regulating kinase 4 2.6977
GPR161 G protein-coupled receptor 161 2.69293
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 2.69205
VIL1 villin 1 2.6897
GYPE glycophorin E (MNS blood group) 2.6814
AVPI1 arginine vasopressin-induced 1 2.67935
ZYX zyxin 2.6768
KATNIP katanin interacting protein 2.66815
CEMIP2 cell migration inducing hyaluronidase 2 2.66425
ZNF764 zinc finger protein 764 2.66293
PGAP6 post-GPI attachment to proteins 6 2.66215
ULBP2 UL16 binding protein 2 2.65945
WIF1 WNT inhibitory factor 1 2.659
CSF3 colony stimulating factor 3 (granulocyte) 2.6576
TPSG1 tryptase gamma 1 2.65045
HBEGF heparin-binding EGF-like growth factor 2.63925
LPIN2 lipin 2 2.63885
ULBP1 UL16 binding protein 1 2.6326
GAL3ST1 galactose-3-O-sulfotransferase 1 2.63235
SGPP1 sphingosine-1-phosphate phosphatase 1 2.63025
JCHAIN joining chain of multimeric IgA and IgM 2.626
SLC66A3 solute carrier family 66 member 3 2.62555
YIPF3 Yip1 domain family, member 3 2.6229
ESYT1 extended synaptotagmin-like protein 1 2.62005
H2BC5 H2B clustered histone 5 2.61815
KLF3 Kruppel-like factor 3 (basic) 2.6162
CELA3B chymotrypsin-like elastase family, member 3B 2.6145
RRAS related RAS viral (r-ras) oncogene homolog 2.6086
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.6064
XDH xanthine dehydrogenase 2.60555
AHSP alpha hemoglobin stabilizing protein 2.59975
TRAK2 trafficking protein, kinesin binding 2 2.59682
FAAP24 FA core complex associated protein 24 2.5882
MAN1A1 mannosidase, alpha, class 1A, member 1 2.58803
STARD8 StAR-related lipid transfer (START) domain containing 8 2.5857
WDR44 WD repeat domain 44 2.58535
PTHLH parathyroid hormone-like hormone 2.58465
RMC1 regulator of MON1-CCZ1 2.58415
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 2.58215
HBZ hemoglobin, zeta 2.57545
MTSS1 metastasis suppressor 1 2.57186
MAPK9 mitogen-activated protein kinase 9 2.57017
SMIM40 small integral membrane protein 40 2.56505
RCOR1 REST corepressor 1 2.56155
LMBR1 limb development membrane protein 1 2.56132
TRIM58 tripartite motif containing 58 2.55585
MACO1 macoilin 1 2.55085
CTRB2 chymotrypsinogen B2 2.543
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.5409
NCK2 NCK adaptor protein 2 2.535
HABP2 hyaluronan binding protein 2 2.53435
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 2.5305
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.5283
NTAN1 N-terminal asparagine amidase 2.52747
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 2.524
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 2.5191
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.519
RAB30 RAB30, member RAS oncogene family 2.5169
MARK3 MAP/microtubule affinity-regulating kinase 3 2.51385
LYN LYN proto-oncogene, Src family tyrosine kinase 2.51045
CES3 carboxylesterase 3 2.50775
LUZP1 leucine zipper protein 1 2.50708
VCL vinculin 2.50502
BMP2 bone morphogenetic protein 2 2.5041
MEAK7 MTOR associated protein, eak-7 homolog 2.49898
ZC4H2 zinc finger, C4H2 domain containing 2.49845
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.49705
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.49485
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.49265
MBOAT2 membrane bound O-acyltransferase domain containing 2 2.49225
H2BC3 H2B clustered histone 3 2.4914
RHD Rh blood group, D antigen 2.4894
EFL1 elongation factor like GTPase 1 2.4881
TESK1 testis-specific kinase 1 2.4852
OLAH oleoyl-ACP hydrolase 2.48195
PICALM phosphatidylinositol binding clathrin assembly protein 2.47618
TAC3 tachykinin 3 2.4746
NPC1L1 NPC1-like 1 2.473
C1QL1 complement component 1, q subcomponent-like 1 2.47055
GAS2L1 growth arrest-specific 2 like 1 2.47012
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.46745
ERC1 ELKS/RAB6-interacting/CAST family member 1 2.4666
FZD5 frizzled class receptor 5 2.45802
BMAL2 basic helix-loop-helix ARNT like 2 2.45665
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.4507
TAAR5 trace amine associated receptor 5 2.4507
RIPOR1 RHO family interacting cell polarization regulator 1 2.44895
VEGFC vascular endothelial growth factor C 2.4486
GATA6 GATA binding protein 6 2.4434
CPA2 carboxypeptidase A2 (pancreatic) 2.44205
CRCT1 cysteine-rich C-terminal 1 2.44105
MYO5A myosin VA (heavy chain 12, myoxin) 2.4406
CDA cytidine deaminase 2.4389
PANX1 pannexin 1 2.4388
DLL3 delta-like 3 (Drosophila) 2.4379
RIMS3 regulating synaptic membrane exocytosis 3 2.4336
GUCA1B guanylate cyclase activator 1B (retina) 2.4331
DAAM2 dishevelled associated activator of morphogenesis 2 2.43305
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 2.43015
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 2.4301
ZNF280A zinc finger protein 280A 2.42965
EPB42 erythrocyte membrane protein band 4.2 2.42945
PGCKA1 PDCD10 and GCKIII kinases associated 1 2.4294
FGF5 fibroblast growth factor 5 2.42462
NOMO3 NODAL modulator 3 2.4199
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.4177
ENAH enabled homolog (Drosophila) 2.41615
PMP22 peripheral myelin protein 22 2.41475
LAP3 leucine aminopeptidase 3 2.414
NGRN neugrin, neurite outgrowth associated 2.4137
APOB apolipoprotein B 2.41175
AVPR1B arginine vasopressin receptor 1B 2.4106
ANPEP alanyl (membrane) aminopeptidase 2.4093
GJD3 gap junction protein, delta 3, 31.9kDa 2.4058
AVEN apoptosis, caspase activation inhibitor 2.40435
LAMC2 laminin, gamma 2 2.40368
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.40202
EIF5A2 eukaryotic translation initiation factor 5A2 2.3993
H2BC14 H2B clustered histone 14 2.3991
COL4A6 collagen, type IV, alpha 6 2.3952
ASB1 ankyrin repeat and SOCS box containing 1 2.39458
ALOXE3 arachidonate lipoxygenase 3 2.39418
DSG2 desmoglein 2 2.393
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2.39295
MAST2 microtubule associated serine/threonine kinase 2 2.39213
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.39057
GC group-specific component (vitamin D binding protein) 2.38755
TRAF3 TNF receptor-associated factor 3 2.38662
KLC3 kinesin light chain 3 2.3856
LGALS4 lectin, galactoside-binding, soluble, 4 2.38425
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 2.38395
MICALL1 MICAL-like 1 2.38363
FZD8 frizzled class receptor 8 2.3828
LRP10 low density lipoprotein receptor-related protein 10 2.38215
UPP1 uridine phosphorylase 1 2.38195
PPOX protoporphyrinogen oxidase 2.3819
RHAG Rh-associated glycoprotein 2.38098
CLIC4 chloride intracellular channel 4 2.38033
ZFYVE9 zinc finger, FYVE domain containing 9 2.37865
CTRL chymotrypsin-like 2.3771
INHBE inhibin, beta E 2.3734
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.37245
RAB40C RAB40C, member RAS oncogene family 2.3723
ADTRP androgen-dependent TFPI-regulating protein 2.37205
RNF126 ring finger protein 126 2.36872
SNAP29 synaptosomal-associated protein, 29kDa 2.3685
DNAH3 dynein, axonemal, heavy chain 3 2.3633
OSBP2 oxysterol binding protein 2 2.36175
SPTA1 spectrin, alpha, erythrocytic 1 2.35975
CTSV cathepsin V 2.3579
SDC4 syndecan 4 2.35585
BLK BLK proto-oncogene, Src family tyrosine kinase 2.35287
USB1 U6 snRNA biogenesis 1 2.35035
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.34925
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.34705
MC5R melanocortin 5 receptor 2.33955
GPR50 G protein-coupled receptor 50 2.3386
DRP2 dystrophin related protein 2 2.3385
CSNK1E casein kinase 1, epsilon 2.33668
TCF12 transcription factor 12 2.3366
FHL2 four and a half LIM domains 2 2.33585
ACVRL1 activin A receptor type II-like 1 2.3337
FOSL1 FOS-like antigen 1 2.3297
ZNF426 zinc finger protein 426 2.32725
EPHA2 EPH receptor A2 2.32605
PTTG1IP pituitary tumor-transforming 1 interacting protein 2.32465
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 2.323
YOD1 YOD1 deubiquitinase 2.3217
CPTP ceramide-1-phosphate transfer protein 2.3215
BPI bactericidal/permeability-increasing protein 2.3195
ARID3A AT rich interactive domain 3A (BRIGHT-like) 2.31805
NXPE4 neurexophilin and PC-esterase domain family, member 4 2.31705
GDF3 growth differentiation factor 3 2.3169
FNDC4 fibronectin type III domain containing 4 2.31535
GPR27 G protein-coupled receptor 27 2.3127
FABP1 fatty acid binding protein 1, liver 2.3117
LEFTY1 left-right determination factor 1 2.3095
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 2.3091
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 2.30775
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.3056
DOK7 docking protein 7 2.30487
DAPK3 death-associated protein kinase 3 2.30358
GRB7 growth factor receptor-bound protein 7 2.3032
FRYL FRY-like 2.30245
RREB1 ras responsive element binding protein 1 2.29917
RAB9A RAB9A, member RAS oncogene family 2.29915
CAPN5 calpain 5 2.2988
ZNF507 zinc finger protein 507 2.29175
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 2.28886
WSB2 WD repeat and SOCS box containing 2 2.2881
C2CD2 C2 calcium-dependent domain containing 2 2.2877
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 2.28635
GAS6 growth arrest-specific 6 2.28335
EZR ezrin 2.2826
SCYL2 SCY1-like 2 (S. cerevisiae) 2.281
DLX6 distal-less homeobox 6 2.2805
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 2.27592
EDC3 enhancer of mRNA decapping 3 2.2718
FOXF1 forkhead box F1 2.26975
NSD1 nuclear receptor binding SET domain protein 1 2.26825
QPRT quinolinate phosphoribosyltransferase 2.2678
FSD1 fibronectin type III and SPRY domain containing 1 2.26705
IER3 immediate early response 3 2.26575
GRM2 glutamate receptor, metabotropic 2 2.2646
TPD52L2 tumor protein D52-like 2 2.26125
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 2.25827
CDC34 cell division cycle 34 2.2577
WWC1 WW and C2 domain containing 1 2.25095
ZNF804A zinc finger protein 804A 2.2505
XKR8 XK, Kell blood group complex subunit-related family, member 8 2.2477
DDA1 DET1 and DDB1 associated 1 2.2476
PRDM10 PR domain containing 10 2.2475
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.24652
TAGLN3 transgelin 3 2.24525
HPCAL1 hippocalcin-like 1 2.24377
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.24315
ROGDI rogdi homolog (Drosophila) 2.24095
PTPN21 protein tyrosine phosphatase, non-receptor type 21 2.23943
LRRK1 leucine-rich repeat kinase 1 2.2392
FGF9 fibroblast growth factor 9 2.2385
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 2.23765
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 2.23633
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2.2346
MEST mesoderm specific transcript 2.23425
OR2H1 olfactory receptor, family 2, subfamily H, member 1 2.23315
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.2322
SH2D3C SH2 domain containing 3C 2.2313
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.23055
KAT2B K(lysine) acetyltransferase 2B 2.23045
BIRC3 baculoviral IAP repeat containing 3 2.2259
BNC1 basonuclin 1 2.2258
ARSJ arylsulfatase family, member J 2.2254
KLF11 Kruppel-like factor 11 2.2235
LALBA lactalbumin, alpha- 2.2234
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.2232
TMPRSS6 transmembrane protease, serine 6 2.22065
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 2.2203
BDKRB1 bradykinin receptor B1 2.21725
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.21635
MNX1 motor neuron and pancreas homeobox 1 2.2162
ALAS1 5'-aminolevulinate synthase 1 2.21595
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 2.21525
TRIM10 tripartite motif containing 10 2.21523
ATXN2 ataxin 2 2.2148
CUZD1 CUB and zona pellucida-like domains 1 2.21225
ZNRF4 zinc and ring finger 4 2.21115
EPB41 erythrocyte membrane protein band 4.1 2.20827
DBN1 drebrin 1 2.20738
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.2048
BCAT1 branched chain amino-acid transaminase 1, cytosolic 2.20435
ALX4 ALX homeobox 4 2.2043
LCT lactase 2.2036
ELOVL6 ELOVL fatty acid elongase 6 2.20202
MYO1A myosin IA 2.2012
SPATA2L spermatogenesis associated 2-like 2.2
IAPP islet amyloid polypeptide 2.1964
TUBAL3 tubulin, alpha-like 3 2.1953
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.19105
PHF13 PHD finger protein 13 2.18965
HYI hydroxypyruvate isomerase (putative) 2.1895
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 2.1877
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 2.18353
TTC21B tetratricopeptide repeat domain 21B 2.1822
CPA1 carboxypeptidase A1 (pancreatic) 2.18195
TMEM53 transmembrane protein 53 2.18155
SOCS1 suppressor of cytokine signaling 1 2.17985
LRRC31 leucine rich repeat containing 31 2.1798
CELA2A chymotrypsin-like elastase family, member 2A 2.17908
FGF4 fibroblast growth factor 4 2.17675
TIMP2 TIMP metallopeptidase inhibitor 2 2.17575
UBE3C ubiquitin protein ligase E3C 2.1739
TES testin LIM domain protein 2.1733
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.1714
CEP170B centrosomal protein 170B 2.1708
ACKR5 atypical chemokine receptor 5 2.16835
ALS2CL ALS2 C-terminal like 2.16765
KDM4A lysine (K)-specific demethylase 4A 2.1675
RND3 Rho family GTPase 3 2.16615
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.1657
SAMD9 sterile alpha motif domain containing 9 2.1647
STX2 syntaxin 2 2.16377
TRIM49D2 tripartite motif containing 49D2 2.1623
LMOD1 leiomodin 1 (smooth muscle) 2.16228
COCH cochlin 2.16175
CCDC69 coiled-coil domain containing 69 2.16085
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.1606
TRPM6 transient receptor potential cation channel, subfamily M, member 6 2.16025
PNLIPRP1 pancreatic lipase-related protein 1 2.1597
TRIM25 tripartite motif containing 25 2.1578
SLC31A2 solute carrier family 31 (copper transporter), member 2 2.1562
GJB3 gap junction protein, beta 3, 31kDa 2.15563
TRIM36 tripartite motif containing 36 2.1552
VAT1 vesicle amine transport 1 2.15345
TMEM143 transmembrane protein 143 2.15345
PTK2 protein tyrosine kinase 2 2.1518
E2F5 E2F transcription factor 5, p130-binding 2.1508
SHBG sex hormone-binding globulin 2.15035
WNT7A wingless-type MMTV integration site family, member 7A 2.1499
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.1486
IL4R interleukin 4 receptor 2.14835
FEM1C fem-1 homolog c (C. elegans) 2.14835
OR5I1 olfactory receptor, family 5, subfamily I, member 1 2.1483
HBQ1 hemoglobin, theta 1 2.14705
GJB4 gap junction protein, beta 4, 30.3kDa 2.1468
CAV2 caveolin 2 2.14517
CCDC87 coiled-coil domain containing 87 2.14405
GPR153 G protein-coupled receptor 153 2.14248
CDHR5 cadherin-related family member 5 2.14197
DIXDC1 DIX domain containing 1 2.1415
LITAF lipopolysaccharide-induced TNF factor 2.14135
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 2.1406
PRODH2 proline dehydrogenase (oxidase) 2 2.1392
PKP1 plakophilin 1 2.13773
SAA4 serum amyloid A4, constitutive 2.1357
CNTFR ciliary neurotrophic factor receptor 2.1357
RTCA RNA 3'-terminal phosphate cyclase 2.13375
R3HCC1L R3H domain and coiled-coil containing 1-like 2.1318
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.13118
PCDHGA9 protocadherin gamma subfamily A, 9 2.1305
C8B complement component 8, beta polypeptide 2.12945
GIPC2 GIPC PDZ domain containing family, member 2 2.1291
CDSN corneodesmosin 2.12762
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.1271
DOCK5 dedicator of cytokinesis 5 2.1244
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 2.1243
PSEN1 presenilin 1 2.12392
PGPEP1 pyroglutamyl-peptidase I 2.1232
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 2.1224
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 2.12195
ZNF215 zinc finger protein 215 2.11765
DUSP5 dual specificity phosphatase 5 2.11685
RUNDC3A RUN domain containing 3A 2.11407
EPPK1 epiplakin 1 2.1136
RNF186 ring finger protein 186 2.1122
PGLYRP1 peptidoglycan recognition protein 1 2.1122
ZDHHC3 zinc finger, DHHC-type containing 3 2.10908
CD24 CD24 molecule 2.10842
GCGR glucagon receptor 2.10535
ZSCAN32 zinc finger and SCAN domain containing 32 2.10363
DCTN1 dynactin 1 2.10343
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.1029
MEFV Mediterranean fever 2.09945
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 2.09905
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 2.099
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 2.09855
ABLIM3 actin binding LIM protein family, member 3 2.09855
CYP3A7-CYP3A51P CYP3A7-CYP3A51P readthrough 2.0971
PARP12 poly (ADP-ribose) polymerase family, member 12 2.09695
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.0966
TMEM40 transmembrane protein 40 2.0965
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 2.0956
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 2.09515
NEU3 sialidase 3 (membrane sialidase) 2.0948
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 2.09415
CELA2B chymotrypsin-like elastase family, member 2B 2.09415
TAGLN transgelin 2.09402
APCS amyloid P component, serum 2.09245
CADM1 cell adhesion molecule 1 2.09222
PLA2G2F phospholipase A2, group IIF 2.0898
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.08875
ZNF33B zinc finger protein 33B 2.08855
FSCN1 fascin actin-bundling protein 1 2.08822
OPTN optineurin 2.08735
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.087
RIPPLY3 ripply transcriptional repressor 3 2.0848
PYGB phosphorylase, glycogen; brain 2.08445
CPT1A carnitine palmitoyltransferase 1A (liver) 2.08325
ADRM1 adhesion regulating molecule 1 2.08205
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.0807
CRYBG2 crystallin beta-gamma domain containing 2 2.08045
GP2 glycoprotein 2 (zymogen granule membrane) 2.08014
TUBA4B tubulin, alpha 4b 2.07845
IFT54 intraflagellar transport 54 2.0776
EGR4 early growth response 4 2.07685
BEST2 bestrophin 2 2.07425
MAN2B2 mannosidase, alpha, class 2B, member 2 2.0739
OSBPL3 oxysterol binding protein-like 3 2.0729
GATAD2A GATA zinc finger domain containing 2A 2.07185
H2BC17 H2B clustered histone 17 2.07105
FYN FYN proto-oncogene, Src family tyrosine kinase 2.07102
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.0702
OLFM4 olfactomedin 4 2.0693
MEX3D mex-3 RNA binding family member D 2.06875
FBXO28 F-box protein 28 2.068
MRC1 mannose receptor, C type 1 2.06685
G6PC1 glucose-6-phosphatase catalytic subunit 1 2.0662
DHCR24 24-dehydrocholesterol reductase 2.06605
ACSM3 acyl-CoA synthetase medium-chain family member 3 2.06507
LOC102724560 cystathionine beta-synthase 2.06485
CYB5R3 cytochrome b5 reductase 3 2.0629
AXL AXL receptor tyrosine kinase 2.06245
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) 2.06235
F3 coagulation factor III (thromboplastin, tissue factor) 2.06135
NCLN nicalin 2.0608
CLPS colipase, pancreatic 2.0593
TMEM35A transmembrane protein 35A 2.0589
SMTN smoothelin 2.05877
APOA2 apolipoprotein A-II 2.05865
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.05815
WFDC1 WAP four-disulfide core domain 1 2.0572
SPANXB1 SPANX family, member B1 2.0567
USP15 ubiquitin specific peptidase 15 2.05518
H2AC6 H2A clustered histone 6 2.055
YTHDC2 YTH domain containing 2 2.05498
WDR47 WD repeat domain 47 2.0543
NCF2 neutrophil cytosolic factor 2 2.0528
IL11 interleukin 11 2.0513
NABP1 nucleic acid binding protein 1 2.04865
FKRP fukutin related protein 2.04865
ITGB7 integrin, beta 7 2.04865
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.04785
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.04655
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.0453
NKX3-2 NK3 homeobox 2 2.045
PLA2G2E phospholipase A2, group IIE 2.0443
NHERF4 NHERF family PDZ scaffold protein 4 2.04235
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.04035
KMT5A lysine methyltransferase 5A 2.03975
GJB1 gap junction protein, beta 1, 32kDa 2.03935
SCRN1 secernin 1 2.03895
SLC7A4 solute carrier family 7, member 4 2.03855
DOT1L DOT1-like histone H3K79 methyltransferase 2.03635
ZFYVE26 zinc finger, FYVE domain containing 26 2.03573
TUBB4A tubulin, beta 4A class IVa 2.03485
SERINC5 serine incorporator 5 2.03445
H2BC21 H2B clustered histone 21 2.03445
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.03245
GCG glucagon 2.0319
RMDN3 regulator of microtubule dynamics 3 2.0316
DPYSL4 dihydropyrimidinase-like 4 2.03127
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.0304
LMX1B LIM homeobox transcription factor 1, beta 2.028
GFRA4 GDNF family receptor alpha 4 2.0279
SAMD4B sterile alpha motif domain containing 4B 2.02735
CNOT6 CCR4-NOT transcription complex, subunit 6 2.0268
OSBPL2 oxysterol binding protein-like 2 2.02635
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.0256
CRISP3 cysteine-rich secretory protein 3 2.02465
DCC DCC netrin 1 receptor 2.0232
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.02295
CCL13 chemokine (C-C motif) ligand 13 2.022
PSG3 pregnancy specific beta-1-glycoprotein 3 2.02182
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.02133
HOXC5 homeobox C5 2.02035
WDR4 WD repeat domain 4 2.02015
CLXN calaxin 2.0201
MMP24 matrix metallopeptidase 24 (membrane-inserted) 2.0185
PRSS58 protease, serine, 58 2.01735
PGLYRP4 peptidoglycan recognition protein 4 2.0166
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 2.01485
C8G complement component 8, gamma polypeptide 2.01465
OR2C1 olfactory receptor, family 2, subfamily C, member 1 2.0143
F9 coagulation factor IX 2.01235
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 2.0119
ZNF710 zinc finger protein 710 2.00977
CA1 carbonic anhydrase I 2.0097
SEC62 SEC62 homolog (S. cerevisiae) 2.00775
SOX1 SRY (sex determining region Y)-box 1 2.0076
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.00535
OCM2 oncomodulin 2 2.00505
MCM3AP minichromosome maintenance complex component 3 associated protein 2.00393
LCOR ligand dependent nuclear receptor corepressor 2.00345
ZFAND3 zinc finger, AN1-type domain 3 2.0033
TUBB2A tubulin, beta 2A class IIa 2.0029
LAMC3 laminin, gamma 3 2.0028
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 2.0028
THPO thrombopoietin 2.002
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.00145
CAV1 caveolin 1, caveolae protein, 22kDa 2.00135

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -10.0
NLRP4 NLR family, pyrin domain containing 4 -8.27465
TOP2A topoisomerase (DNA) II alpha 170kDa -7.2618
CDK1 cyclin-dependent kinase 1 -7.24578
PCNA proliferating cell nuclear antigen -7.15525
HOXA5 homeobox A5 -6.86445
CDC25B cell division cycle 25B -6.7492
MRPS2 mitochondrial ribosomal protein S2 -6.277
PSRC1 proline/serine-rich coiled-coil 1 -5.80835
DDIT4 DNA-damage-inducible transcript 4 -5.7694
RPIA ribose 5-phosphate isomerase A -5.65225
CDK4 cyclin-dependent kinase 4 -5.556
KIF20A kinesin family member 20A -5.52535
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -5.43875
OXA1L oxidase (cytochrome c) assembly 1-like -5.2035
YME1L1 YME1-like 1 ATPase -5.19925
FABP5 fatty acid binding protein 5 (psoriasis-associated) -5.0
BOLA1 bolA family member 1 -4.9378
DYNLT3 dynein, light chain, Tctex-type 3 -4.71835
ENOPH1 enolase-phosphatase 1 -4.6527
DCK deoxycytidine kinase -4.6489
CCNB2 cyclin B2 -4.56135
KIF11 kinesin family member 11 -4.4532
ACOT9 acyl-CoA thioesterase 9 -4.3717
AURKB aurora kinase B -4.25595
SNRPB2 small nuclear ribonucleoprotein polypeptide B -4.24515
TEX10 testis expressed 10 -4.2179
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.2023
NUSAP1 nucleolar and spindle associated protein 1 -4.1686
TMEM38B transmembrane protein 38B -4.1607
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -4.1431
KHDC4 KH domain containing 4, pre-mRNA splicing factor -4.13745
NXT1 nuclear transport factor 2-like export factor 1 -4.12485
HADH hydroxyacyl-CoA dehydrogenase -4.07377
BAG3 BCL2-associated athanogene 3 -4.065
UFM1 ubiquitin-fold modifier 1 -4.01435
LACTB2 lactamase, beta 2 -3.99355
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -3.95837
RYR1 ryanodine receptor 1 (skeletal) -3.9374
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -3.9276
TBC1D10C TBC1 domain family, member 10C -3.87855
GNPDA1 glucosamine-6-phosphate deaminase 1 -3.82728
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.7875
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.77245
KANSL1 KAT8 regulatory NSL complex subunit 1 -3.67015
SESN1 sestrin 1 -3.65505
MKKS McKusick-Kaufman syndrome -3.65005
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -3.57495
PMVK phosphomevalonate kinase -3.5328
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.4989
KIF15 kinesin family member 15 -3.4556
TRMT5 tRNA methyltransferase 5 -3.45505
GTPBP8 GTP-binding protein 8 (putative) -3.4423
CCNA2 cyclin A2 -3.41873
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -3.40805
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -3.39315
ANKRD10 ankyrin repeat domain 10 -3.37475
CRIPT cysteine-rich PDZ-binding protein -3.3733
BASP1 brain abundant, membrane attached signal protein 1 -3.36645
MACROD1 MACRO domain containing 1 -3.3641
MTERF3 mitochondrial transcription termination factor 3 -3.36275
TTK TTK protein kinase -3.35305
PLK1 polo-like kinase 1 -3.35305
PTCD3 pentatricopeptide repeat domain 3 -3.3457
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.32965
USP19 ubiquitin specific peptidase 19 -3.3135
STMN1 stathmin 1 -3.31075
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -3.30205
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -3.28745
CREG1 cellular repressor of E1A-stimulated genes 1 -3.2671
HSPA14 heat shock 70kDa protein 14 -3.2499
PPA2 pyrophosphatase (inorganic) 2 -3.24935
TSC22D3 TSC22 domain family, member 3 -3.23997
DDB2 damage-specific DNA binding protein 2, 48kDa -3.2375
CIRBP cold inducible RNA binding protein -3.21953
NAT10 N-acetyltransferase 10 (GCN5-related) -3.21805
MIS12 MIS12 kinetochore complex component -3.21795
TFAM transcription factor A, mitochondrial -3.21782
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -3.21705
DNM1 dynamin 1 -3.20425
HMGB2 high mobility group box 2 -3.19645
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -3.19405
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.18035
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -3.1789
BRD3 bromodomain containing 3 -3.14393
MDH1 malate dehydrogenase 1, NAD (soluble) -3.1401
ENTR1 endosome associated trafficking regulator 1 -3.14
CETN3 centrin, EF-hand protein, 3 -3.1277
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.12485
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.11515
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -3.0945
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.0934
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.08935
BLCAP bladder cancer associated protein -3.08235
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.05865
CEP55 centrosomal protein 55kDa -3.04715
PCLAF PCNA clamp associated factor -3.04675
SELL selectin L -3.0227
RCC1L RCC1 like -3.00535
GPSM2 G-protein signaling modulator 2 -3.0043
COG2 component of oligomeric golgi complex 2 -2.9979
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.9942
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.9593
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.94765
TFB2M transcription factor B2, mitochondrial -2.93495
ZDHHC6 zinc finger, DHHC-type containing 6 -2.9273
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -2.91255
PMPCA peptidase (mitochondrial processing) alpha -2.9112
CDCA4 cell division cycle associated 4 -2.91005
ADI1 acireductone dioxygenase 1 -2.907
SUOX sulfite oxidase -2.9026
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.89665
SPPL2A signal peptide peptidase like 2A -2.8962
CENPA centromere protein A -2.89577
ZWINT ZW10 interacting kinetochore protein -2.89145
NR1D2 nuclear receptor subfamily 1, group D, member 2 -2.8876
CASC3 cancer susceptibility candidate 3 -2.885
HOXA10-HOXA9 HOXA10-HOXA9 readthrough -2.87685
MYOT myotilin -2.86795
ABHD10 abhydrolase domain containing 10 -2.8631
FBXO5 F-box protein 5 -2.85805
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.84525
C2CD5 C2 calcium-dependent domain containing 5 -2.84485
SNU13 small nuclear ribonucleoprotein 13 -2.84438
MGST2 microsomal glutathione S-transferase 2 -2.8428
PTTG1 pituitary tumor-transforming 1 -2.84165
PBK PDZ binding kinase -2.8289
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.82767
PIMREG PICALM interacting mitotic regulator -2.82735
DENND1C DENN/MADD domain containing 1C -2.8105
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.80293
CHL1 cell adhesion molecule L1-like -2.79615
STX10 syntaxin 10 -2.79455
RBM14-RBM4 RBM14-RBM4 readthrough -2.7911
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.7878
KIF18B kinesin family member 18B -2.7782
TIPRL TOR signaling pathway regulator -2.77695
TSKU tsukushi, small leucine rich proteoglycan -2.7715
VRK1 vaccinia related kinase 1 -2.76855
HAUS4 HAUS augmin-like complex, subunit 4 -2.76235
MPV17 MpV17 mitochondrial inner membrane protein -2.74685
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.7431
SNX5 sorting nexin 5 -2.74025
SRSF7 serine/arginine-rich splicing factor 7 -2.73983
PUM2 pumilio RNA-binding family member 2 -2.73193
DSN1 DSN1, MIS12 kinetochore complex component -2.72235
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.72185
RMI1 RecQ mediated genome instability 1 -2.72115
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -2.7211
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.70668
EAPP E2F-associated phosphoprotein -2.70305
FBXO3 F-box protein 3 -2.7002
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.6982
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.6981
CKAP2 cytoskeleton associated protein 2 -2.69105
SSNA1 Sjogren syndrome nuclear autoantigen 1 -2.68935
MRPL23 mitochondrial ribosomal protein L23 -2.68515
HOXA4 homeobox A4 -2.68195
MTPAP mitochondrial poly(A) polymerase -2.6779
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.67715
CUEDC2 CUE domain containing 2 -2.67515
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -2.6714
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.6714
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.67005
ATRIP ATR interacting protein -2.66377
BANF1 barrier to autointegration factor 1 -2.66275
RXRA retinoid X receptor, alpha -2.66232
TPX2 TPX2, microtubule-associated -2.65645
PSIP1 PC4 and SFRS1 interacting protein 1 -2.65642
RACGAP1 Rac GTPase activating protein 1 -2.64835
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.64565
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.64455
PTPRA protein tyrosine phosphatase, receptor type, A -2.63984
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.6359
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.6354
MRPS18B mitochondrial ribosomal protein S18B -2.6322
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.63155
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -2.62828
FAM216A family with sequence similarity 216, member A -2.61975
RPS9 ribosomal protein S9 -2.61838
IARS1 isoleucyl-tRNA synthetase 1 -2.61475
CAMLG calcium modulating ligand -2.6097
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -2.60535
COPS4 COP9 signalosome subunit 4 -2.6041
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -2.60155
COMMD3-BMI1 COMMD3-BMI1 readthrough -2.5975
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.5949
KRT10 keratin 10, type I -2.59305
FAM111A family with sequence similarity 111, member A -2.5813
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) -2.5809
UNG uracil-DNA glycosylase -2.5793
CD320 CD320 molecule -2.5784
CDC45 cell division cycle 45 -2.5771
CDC23 cell division cycle 23 -2.5727
GADD45B growth arrest and DNA-damage-inducible, beta -2.57083
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.5692
TMEM267 transmembrane protein 267 -2.56895
DEK DEK proto-oncogene -2.5662
ADGRG2 adhesion G protein-coupled receptor G2 -2.56355
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -2.5623
MEPCE methylphosphate capping enzyme -2.55795
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.55745
ACOT2 acyl-CoA thioesterase 2 -2.55595
XPO1 exportin 1 -2.5556
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.5549
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.55025
ABITRAM actin binding transcription modulator -2.54955
BZW2 basic leucine zipper and W2 domains 2 -2.54795
MELK maternal embryonic leucine zipper kinase -2.5463
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.5459
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -2.54585
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -2.54015
TRIM68 tripartite motif containing 68 -2.5385
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.5379
AMDHD2 amidohydrolase domain containing 2 -2.5304
SDAD1 SDA1 domain containing 1 -2.529
KIF4A kinesin family member 4A -2.5242
GMPR2 guanosine monophosphate reductase 2 -2.5206
PPP6C protein phosphatase 6, catalytic subunit -2.51303
PRR7 proline rich 7 (synaptic) -2.50665
PEX11B peroxisomal biogenesis factor 11 beta -2.50135
TNNI2 troponin I type 2 (skeletal, fast) -2.50045
SLN sarcolipin -2.49565
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.49455
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -2.48617
IPO7 importin 7 -2.48295
POMZP3 POM121 and ZP3 fusion -2.48292
PHYH phytanoyl-CoA 2-hydroxylase -2.47465
COASY CoA synthase -2.47243
TTI1 TELO2 interacting protein 1 -2.46725
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.4672
TP53 tumor protein p53 -2.46532
YEATS4 YEATS domain containing 4 -2.465
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.46182
SIVA1 SIVA1, apoptosis-inducing factor -2.45942
TROAP trophinin associated protein -2.45345
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) -2.45235
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.4509
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -2.4478
SDHAF1 succinate dehydrogenase complex assembly factor 1 -2.4471
MAGED4B melanoma antigen family D4B -2.4451
ETFB electron-transfer-flavoprotein, beta polypeptide -2.4451
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -2.4443
SMAD5 SMAD family member 5 -2.44365
PGAM2 phosphoglycerate mutase 2 (muscle) -2.4398
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -2.43937
LBHD1 LBH domain containing 1 -2.431
SNX17 sorting nexin 17 -2.4303
PRUNE1 prune exopolyphosphatase 1 -2.42803
MRPS16 mitochondrial ribosomal protein S16 -2.42795
MED4 mediator complex subunit 4 -2.42335
LYRM1 LYR motif containing 1 -2.42085
PCYOX1L prenylcysteine oxidase 1 like -2.4195
SEC23B Sec23 homolog B (S. cerevisiae) -2.41865
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.4162
MCRS1 microspherule protein 1 -2.41575
NUP54 nucleoporin 54kDa -2.41525
DACH1 dachshund family transcription factor 1 -2.41328
CATSPER2 cation channel, sperm associated 2 -2.4105
AK8 adenylate kinase 8 -2.4101
PNPO pyridoxamine 5'-phosphate oxidase -2.40915
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -2.40788
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -2.40435
RFK riboflavin kinase -2.39972
RBL1 retinoblastoma-like 1 -2.3988
DBF4 DBF4 zinc finger -2.39265
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -2.3922
PHF2 PHD finger protein 2 -2.38475
RBM39 RNA binding motif protein 39 -2.3834
TM9SF1 transmembrane 9 superfamily member 1 -2.38283
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.37715
HEATR1 HEAT repeat containing 1 -2.37358
BORCS6 BLOC-1 related complex subunit 6 -2.3662
TSC22D4 TSC22 domain family, member 4 -2.36495
PUS1 pseudouridylate synthase 1 -2.36345
MRPL3 mitochondrial ribosomal protein L3 -2.3621
APOO apolipoprotein O -2.35625
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -2.35545
SPATS2 spermatogenesis associated, serine-rich 2 -2.35335
PRPF4 pre-mRNA processing factor 4 -2.35287
PCDH9 protocadherin 9 -2.34413
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.34305
BIRC5 baculoviral IAP repeat containing 5 -2.34297
HAUS7 HAUS augmin-like complex, subunit 7 -2.34223
PCNP PEST proteolytic signal containing nuclear protein -2.3398
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.3392
CST3 cystatin C -2.33855
MDC1 mediator of DNA-damage checkpoint 1 -2.33763
TNRC6B trinucleotide repeat containing 6B -2.33315
TCEAL1 transcription elongation factor A (SII)-like 1 -2.33005
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.32815
HLA-DMA major histocompatibility complex, class II, DM alpha -2.32635
CENPS-CORT CENPS-CORT readthrough -2.3263
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -2.3261
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -2.3215
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -2.32018
ACTA2 actin, alpha 2, smooth muscle, aorta -2.3176
CCNF cyclin F -2.3174
COQ6 coenzyme Q6 monooxygenase -2.31705
H2AX H2A.X variant histone -2.31435
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.31255
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 -2.31
DCXR dicarbonyl/L-xylulose reductase -2.3072
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.30595
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 -2.2998
MYL11 myosin light chain 11 -2.29785
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) -2.29565
ACTL6A actin-like 6A -2.29495
TENM4 teneurin transmembrane protein 4 -2.29435
ATRAID all-trans retinoic acid-induced differentiation factor -2.29425
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.28385
CENPN centromere protein N -2.27995
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -2.27863
LOC124904395 uncharacterized LOC124904395 -2.27801
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.27645
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.27205
TRMT61B tRNA methyltransferase 61B -2.2711
H2AZ1 H2A.Z variant histone 1 -2.26675
LDHD lactate dehydrogenase D -2.26455
TSPAN6 tetraspanin 6 -2.26027
ZNF862 zinc finger protein 862 -2.2571
MCM7 minichromosome maintenance complex component 7 -2.25583
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.25522
LONP2 lon peptidase 2, peroxisomal -2.2547
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.25395
RPS27L ribosomal protein S27-like -2.25145
TRIM28 tripartite motif containing 28 -2.2495
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.24755
NCOA4 nuclear receptor coactivator 4 -2.24495
BATF3 basic leucine zipper transcription factor, ATF-like 3 -2.2427
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.23555
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.23365
ST20-MTHFS ST20-MTHFS readthrough -2.2335
WAS Wiskott-Aldrich syndrome -2.23042
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -2.22535
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -2.22375
ARF5 ADP-ribosylation factor 5 -2.21995
METTL25B methyltransferase like 25B -2.21925
MSL1 male-specific lethal 1 homolog (Drosophila) -2.21865
SIX1 SIX homeobox 1 -2.21735
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.2171
TMCO1 transmembrane and coiled-coil domains 1 -2.21693
PGM1 phosphoglucomutase 1 -2.2167
MYH6 myosin, heavy chain 6, cardiac muscle, alpha -2.21467
ZBTB38 zinc finger and BTB domain containing 38 -2.21445
ZBED5 zinc finger, BED-type containing 5 -2.21135
MEOX1 mesenchyme homeobox 1 -2.2108
CCNT1 cyclin T1 -2.2102
UBB ubiquitin B -2.2087
SRP54 signal recognition particle 54kDa -2.2083
TSFM Ts translation elongation factor, mitochondrial -2.20802
NIPSNAP2 nipsnap homolog 2 -2.2069
SNRPG small nuclear ribonucleoprotein polypeptide G -2.2067
ZNF26 zinc finger protein 26 -2.20665
ZMYND11 zinc finger, MYND-type containing 11 -2.2065
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.2058
LRRC20 leucine rich repeat containing 20 -2.2044
TCF15 transcription factor 15 (basic helix-loop-helix) -2.19625
CNIH3 cornichon family AMPA receptor auxiliary protein 3 -2.19575
USF2 upstream transcription factor 2, c-fos interacting -2.19263
MRPS33 mitochondrial ribosomal protein S33 -2.19205
RAB5IF RAB5 interacting factor -2.18955
ZBTB35 zinc finger and BTB domain containing 35 -2.18847
TOMM70 translocase of outer mitochondrial membrane 70 -2.18228
TWNK twinkle mtDNA helicase -2.17845
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -2.1777
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.17685
EPHB6 EPH receptor B6 -2.1734
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.1731
LIPT1 lipoyltransferase 1 -2.17045
RALY RALY heterogeneous nuclear ribonucleoprotein -2.17035
OXLD1 oxidoreductase-like domain containing 1 -2.16985
WDR83OS WD repeat domain 83 opposite strand -2.16855
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.16795
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -2.1679
THADA thyroid adenoma associated -2.16398
EMX2 empty spiracles homeobox 2 -2.16335
BET1 Bet1 golgi vesicular membrane trafficking protein -2.16265
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.15995
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -2.15865
SETMAR SET domain and mariner transposase fusion gene -2.15385
XPC xeroderma pigmentosum, complementation group C -2.15165
ASF1B anti-silencing function 1B histone chaperone -2.15065
DCLRE1C DNA cross-link repair 1C -2.14573
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.1444
NEK4 NIMA-related kinase 4 -2.14235
VAV3 vav 3 guanine nucleotide exchange factor -2.14202
EIF3E eukaryotic translation initiation factor 3, subunit E -2.1416
PTDSS1 phosphatidylserine synthase 1 -2.14145
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.1411
PDHB pyruvate dehydrogenase (lipoamide) beta -2.13772
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.13245
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -2.12965
MRPS31 mitochondrial ribosomal protein S31 -2.12687
COQ4 coenzyme Q4 -2.12595
RFC2 replication factor C (activator 1) 2, 40kDa -2.12465
FBL fibrillarin -2.1203
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.1198
E2F8 E2F transcription factor 8 -2.11905
MCM6 minichromosome maintenance complex component 6 -2.1184
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.11635
CDK5RAP1 CDK5 regulatory subunit associated protein 1 -2.11475
PUF60 poly-U binding splicing factor 60KDa -2.1131
HMGB1 high mobility group box 1 -2.11065
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -2.10995
FOSB FBJ murine osteosarcoma viral oncogene homolog B -2.1091
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.10665
CGREF1 cell growth regulator with EF-hand domain 1 -2.10595
QARS1 glutaminyl-tRNA synthetase 1 -2.10565
ETV1 ets variant 1 -2.10555
NUP133 nucleoporin 133kDa -2.1042
HDAC7 histone deacetylase 7 -2.10245
TPGS1 tubulin polyglutamylase complex subunit 1 -2.10185
KIF23 kinesin family member 23 -2.10185
HOXA10 homeobox A10 -2.09425
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.094
TXNDC9 thioredoxin domain containing 9 -2.0916
RPL17-C18ORF32 RPL17-C18orf32 readthrough -2.0904
RHOBTB1 Rho-related BTB domain containing 1 -2.08775
PCIF1 PDX1 C-terminal inhibiting factor 1 -2.08641
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -2.08545
TNNI1 troponin I type 1 (skeletal, slow) -2.08305
RYK receptor-like tyrosine kinase -2.08168
TMED1 transmembrane emp24 protein transport domain containing 1 -2.0788
RPL39L ribosomal protein L39-like -2.07855
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -2.07735
TRIM66 tripartite motif containing 66 -2.07735
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 -2.07645
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -2.07585
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.07337
RXYLT1 ribitol xylosyltransferase 1 -2.07308
ZNF706 zinc finger protein 706 -2.0727
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.07115
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.07075
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -2.0704
ZNHIT3 zinc finger, HIT-type containing 3 -2.06945
GRAMD1B GRAM domain containing 1B -2.0673
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.06635
TNNC2 troponin C type 2 (fast) -2.06555
APIP APAF1 interacting protein -2.06485
ZBTB25 zinc finger and BTB domain containing 25 -2.0624
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.0624
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B -2.05767
PHGDH phosphoglycerate dehydrogenase -2.05665
ERH enhancer of rudimentary homolog (Drosophila) -2.0553
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.0542
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.05325
ZNF783 zinc finger family member 783 -2.0504
PRKCD protein kinase C, delta -2.04935
IFRD2 interferon-related developmental regulator 2 -2.04932
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.04667
BAHCC1 BAH domain and coiled-coil containing 1 -2.04605
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -2.04572
REPIN1 replication initiator 1 -2.0454
RNMT RNA (guanine-7-) methyltransferase -2.04538
COMMD3 COMM domain containing 3 -2.04385
NOP56 NOP56 ribonucleoprotein -2.04183
FEN1 flap structure-specific endonuclease 1 -2.04157
HSPB2 heat shock 27kDa protein 2 -2.04095
ARL10 ADP-ribosylation factor-like 10 -2.0408
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.04045
NPR2 natriuretic peptide receptor 2 -2.0383
CPVL carboxypeptidase, vitellogenic-like -2.03665
ACOD1 aconitate decarboxylase 1 -2.03245
EIF6 eukaryotic translation initiation factor 6 -2.0317
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -2.03165
VAV1 vav 1 guanine nucleotide exchange factor -2.03065
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -2.03045
CGRRF1 cell growth regulator with ring finger domain 1 -2.0292
PER3 period circadian clock 3 -2.0284
RPA3 replication protein A3, 14kDa -2.02605
EXOSC8 exosome component 8 -2.0249
STAT1 signal transducer and activator of transcription 1, 91kDa -2.02445
ZNF248 zinc finger protein 248 -2.02415
SLC25A38 solute carrier family 25, member 38 -2.02415
CUTC cutC copper transporter -2.0236
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -2.02335
CFAP20 cilia and flagella associated protein 20 -2.0222
HJURP Holliday junction recognition protein -2.02145
MORC4 MORC family CW-type zinc finger 4 -2.01835
RBBP4 retinoblastoma binding protein 4 -2.0162
TPM3 tropomyosin 3 -2.0157
PRMT3 protein arginine methyltransferase 3 -2.0156
F2R coagulation factor II (thrombin) receptor -2.0136
RPP30 ribonuclease P/MRP 30kDa subunit -2.01205
SYF2 SYF2 pre-mRNA-splicing factor -2.0081
USP39 ubiquitin specific peptidase 39 -2.008
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -2.0077
GLUL glutamate-ammonia ligase -2.00755
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.0053
VTA1 vesicle (multivesicular body) trafficking 1 -2.005