CRCGN017_MCF10A.WT.HP_24H:E08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description rotenone 33.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

541 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:E08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STXBP1 syntaxin binding protein 1 6.32235
ABHD4 abhydrolase domain containing 4 5.2851
TNIP1 TNFAIP3 interacting protein 1 5.20145
PPARG peroxisome proliferator-activated receptor gamma 5.16745
ADGRE5 adhesion G protein-coupled receptor E5 5.08105
WIF1 WNT inhibitory factor 1 5.0
TBX2 T-box 2 4.945
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 4.91505
CXCL2 chemokine (C-X-C motif) ligand 2 4.85755
AGR2 anterior gradient 2 4.80435
OXSR1 oxidative stress responsive 1 4.72085
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.44915
MYH9 myosin, heavy chain 9, non-muscle 4.31545
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.29895
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 4.2653
RGS2 regulator of G-protein signaling 2 3.98595
TPD52L2 tumor protein D52-like 2 3.9377
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 3.9309
DUSP14 dual specificity phosphatase 14 3.79365
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.76475
DUSP4 dual specificity phosphatase 4 3.73762
TICAM1 toll-like receptor adaptor molecule 1 3.73355
TCTN1 tectonic family member 1 3.6952
EPN2 epsin 2 3.65992
SMAD3 SMAD family member 3 3.65774
MSRA methionine sulfoxide reductase A 3.58905
CAB39 calcium binding protein 39 3.54515
KDM5A lysine (K)-specific demethylase 5A 3.50225
PTPN1 protein tyrosine phosphatase, non-receptor type 1 3.4955
PLEK2 pleckstrin 2 3.43485
TGFA transforming growth factor, alpha 3.40907
LRP10 low density lipoprotein receptor-related protein 10 3.36575
RRAS related RAS viral (r-ras) oncogene homolog 3.3597
HBEGF heparin-binding EGF-like growth factor 3.33315
TP53BP2 tumor protein p53 binding protein 2 3.27485
FHL2 four and a half LIM domains 2 3.22665
MEAK7 MTOR associated protein, eak-7 homolog 3.19855
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 3.19722
DDA1 DET1 and DDB1 associated 1 3.18165
CRELD2 cysteine-rich with EGF-like domains 2 3.10625
NRBF2 nuclear receptor binding factor 2 3.1055
SQOR sulfide quinone oxidoreductase 3.0981
VAT1 vesicle amine transport 1 3.0285
WSB2 WD repeat and SOCS box containing 2 3.02635
FSTL3 follistatin-like 3 (secreted glycoprotein) 3.00705
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.94948
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.9478
CLIC4 chloride intracellular channel 4 2.93982
CDCP1 CUB domain containing protein 1 2.9112
NCK2 NCK adaptor protein 2 2.9035
EPHA2 EPH receptor A2 2.86785
LAMC2 laminin, gamma 2 2.8438
AFF4 AF4/FMR2 family, member 4 2.82745
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.8165
CDA cytidine deaminase 2.78625
CHIC2 cysteine-rich hydrophobic domain 2 2.7646
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.75977
MANF mesencephalic astrocyte-derived neurotrophic factor 2.7579
H2BC12 H2B clustered histone 12 2.75607
IL1A interleukin 1, alpha 2.735
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2.72535
LSR lipolysis stimulated lipoprotein receptor 2.71925
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 2.70147
G0S2 G0/G1 switch 2 2.7
LUZP1 leucine zipper protein 1 2.69747
S100P S100 calcium binding protein P 2.695
LAMB3 laminin, beta 3 2.69465
CAVIN1 caveolae associated protein 1 2.6883
TIMP2 TIMP metallopeptidase inhibitor 2 2.68635
KCTD5 potassium channel tetramerization domain containing 5 2.6656
MTCH1 mitochondrial carrier 1 2.66445
BMAL2 basic helix-loop-helix ARNT like 2 2.66215
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.6432
MISP mitotic spindle positioning 2.61795
EMP3 epithelial membrane protein 3 2.61325
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.60165
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.59613
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 2.57967
INF2 inverted formin, FH2 and WH2 domain containing 2.57175
WWC1 WW and C2 domain containing 1 2.561
KIF2A kinesin heavy chain member 2A 2.55797
ESYT1 extended synaptotagmin-like protein 1 2.55415
STK25 serine/threonine kinase 25 2.5516
ELAVL1 ELAV like RNA binding protein 1 2.55025
IL1B interleukin 1, beta 2.54315
WDR1 WD repeat domain 1 2.54303
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.53965
FOSL1 FOS-like antigen 1 2.53955
CLIP2 CAP-GLY domain containing linker protein 2 2.5394
MICALL1 MICAL-like 1 2.53452
AVEN apoptosis, caspase activation inhibitor 2.53295
EHD1 EH-domain containing 1 2.53237
FIP1L1 factor interacting with PAPOLA and CPSF1 2.5253
LRRC59 leucine rich repeat containing 59 2.51865
SAP30BP SAP30 binding protein 2.51365
PTHLH parathyroid hormone-like hormone 2.50962
ULBP2 UL16 binding protein 2 2.5068
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 2.49885
OPTN optineurin 2.48922
SQLE squalene epoxidase 2.48852
CEMIP2 cell migration inducing hyaluronidase 2 2.4743
PEA15 phosphoprotein enriched in astrocytes 15 2.47165
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.4716
STX4 syntaxin 4 2.47125
ELOVL1 ELOVL fatty acid elongase 1 2.4697
TMEM184B transmembrane protein 184B 2.46015
PALLD palladin, cytoskeletal associated protein 2.45692
IER3 immediate early response 3 2.4559
DYNLT1 dynein, light chain, Tctex-type 1 2.4405
ITGB4 integrin, beta 4 2.43971
HMOX1 heme oxygenase 1 2.43875
BAG3 BCL2-associated athanogene 3 2.43225
MYL9 myosin, light chain 9, regulatory 2.42045
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 2.4126
WNT5B wingless-type MMTV integration site family, member 5B 2.4084
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.407
ACOT9 acyl-CoA thioesterase 9 2.40545
CCDC68 coiled-coil domain containing 68 2.37455
AVPI1 arginine vasopressin-induced 1 2.3624
SH3D19 SH3 domain containing 19 2.36005
SDC4 syndecan 4 2.3565
STXBP2 syntaxin binding protein 2 2.3525
RFTN1 raftlin, lipid raft linker 1 2.3269
RASAL2 RAS protein activator like 2 2.31875
RPP38 ribonuclease P/MRP 38kDa subunit 2.3091
CYB5R3 cytochrome b5 reductase 3 2.3066
RALB v-ral simian leukemia viral oncogene homolog B 2.30443
ZBED2 zinc finger, BED-type containing 2 2.30045
RHOC ras homolog family member C 2.2964
CDR2L cerebellar degeneration-related protein 2-like 2.29505
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.29375
ITGAV integrin, alpha V 2.28745
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.2819
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 2.2781
PMP22 peripheral myelin protein 22 2.27809
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 2.27535
USB1 U6 snRNA biogenesis 1 2.27095
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.27045
TMEM40 transmembrane protein 40 2.27025
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 2.2693
CNN2 calponin 2 2.26865
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.261
EHD4 EH-domain containing 4 2.2607
ANXA3 annexin A3 2.2548
TOR4A torsin family 4, member A 2.24935
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.2474
PAQR4 progestin and adipoQ receptor family member IV 2.2457
BCAR3 breast cancer anti-estrogen resistance 3 2.24455
MAP7D1 MAP7 domain containing 1 2.23225
LITAF lipopolysaccharide-induced TNF factor 2.2307
IL2RA interleukin 2 receptor, alpha 2.22867
PALM2AKAP2 PALM2 and AKAP2 fusion 2.22825
DEF8 differentially expressed in FDCP 8 homolog (mouse) 2.2278
SMTN smoothelin 2.22263
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.2212
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.22045
CXCL8 chemokine (C-X-C motif) ligand 8 2.21983
STX2 syntaxin 2 2.21703
EDC3 enhancer of mRNA decapping 3 2.21545
STK10 serine/threonine kinase 10 2.2154
DHCR24 24-dehydrocholesterol reductase 2.21255
PWWP3A PWWP domain containing 3A, DNA repair factor 2.2064
COL17A1 collagen, type XVII, alpha 1 2.20275
H2BC9 H2B clustered histone 9 2.2015
DUSP7 dual specificity phosphatase 7 2.19852
S100A12 S100 calcium binding protein A12 2.1891
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.18353
ADIPOR2 adiponectin receptor 2 2.18025
RAB8A RAB8A, member RAS oncogene family 2.17955
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.17685
MVP major vault protein 2.17565
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.17545
SAP30L SAP30-like 2.17445
PLAU plasminogen activator, urokinase 2.16895
TSPAN1 tetraspanin 1 2.153
CCDC88A coiled-coil domain containing 88A 2.14937
PKP1 plakophilin 1 2.14815
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.1466
TRAF1 TNF receptor-associated factor 1 2.1369
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.1353
NECAP2 NECAP endocytosis associated 2 2.1323
ALAS1 5'-aminolevulinate synthase 1 2.1271
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.1215
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.11575
PLA2G15 phospholipase A2, group XV 2.1114
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 2.10635
KLRB1 killer cell lectin-like receptor subfamily B, member 1 2.10465
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.10295
CDC37 cell division cycle 37 2.10265
ACTN4 actinin, alpha 4 2.1022
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.0987
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.09707
PLAUR plasminogen activator, urokinase receptor 2.0896
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.0816
TRIM36 tripartite motif containing 36 2.07925
FYN FYN proto-oncogene, Src family tyrosine kinase 2.07853
LRRC36 leucine rich repeat containing 36 2.0777
FOXD1 forkhead box D1 2.0776
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 2.0766
TFF1 trefoil factor 1 2.0706
H2AC19 H2A clustered histone 19 2.06993
CAV2 caveolin 2 2.06913
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 2.067
WWC2 WW and C2 domain containing 2 2.0664
GLIPR1 GLI pathogenesis-related 1 2.06323
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.06315
BMP2 bone morphogenetic protein 2 2.06
FGFBP1 fibroblast growth factor binding protein 1 2.05795
CORO1C coronin, actin binding protein, 1C 2.056
SCYL2 SCY1-like 2 (S. cerevisiae) 2.05465
TES testin LIM domain protein 2.0516
DAPK3 death-associated protein kinase 3 2.0479
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 2.0474
ANKLE2 ankyrin repeat and LEM domain containing 2 2.0451
STX18 syntaxin 18 2.0443
PGCKA1 PDCD10 and GCKIII kinases associated 1 2.04415
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.04415
LIMA1 LIM domain and actin binding 1 2.0397
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.0382
LMTK1 lemur tail kinase 1 2.03655
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.0354
PLEC plectin 2.03527
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 2.0347
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 2.03468
MSTO1 misato 1, mitochondrial distribution and morphology regulator 2.0309
DERL1 derlin 1 2.02663
ZC3H12A zinc finger CCCH-type containing 12A 2.02565
SH2B3 SH2B adaptor protein 3 2.02465
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.0246
CCL17 chemokine (C-C motif) ligand 17 2.02425
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 2.0174
FAF2 Fas associated factor family member 2 2.01545
ATOSB atos homolog B 2.0132
VEGFC vascular endothelial growth factor C 2.01195
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 2.01168
EZR ezrin 2.01152
RNF11 ring finger protein 11 2.01075
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.0106
NPC1 Niemann-Pick disease, type C1 2.00745
HPCAL1 hippocalcin-like 1 2.00723
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 2.00487
TPST2 tyrosylprotein sulfotransferase 2 2.00425
TSPAN8 tetraspanin 8 2.00425
PRSS3 protease, serine, 3 2.0029

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -10.0
TOP2A topoisomerase (DNA) II alpha 170kDa -7.52817
CDK1 cyclin-dependent kinase 1 -7.20683
CDK4 cyclin-dependent kinase 4 -6.4246
HOXA5 homeobox A5 -6.2702
CDC25B cell division cycle 25B -5.384
NLRP4 NLR family, pyrin domain containing 4 -5.33775
ANKRD10 ankyrin repeat domain 10 -4.92875
DDIT4 DNA-damage-inducible transcript 4 -4.80835
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.7931
KIF11 kinesin family member 11 -4.70935
TP53 tumor protein p53 -4.63328
NUSAP1 nucleolar and spindle associated protein 1 -4.5815
AURKB aurora kinase B -4.44945
SESN1 sestrin 1 -4.34835
NUP133 nucleoporin 133kDa -4.32425
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -4.2938
HADH hydroxyacyl-CoA dehydrogenase -4.27607
PSRC1 proline/serine-rich coiled-coil 1 -4.26575
C1QBP complement component 1, q subcomponent binding protein -4.22265
S100A8 S100 calcium binding protein A8 -4.16935
TSC22D3 TSC22 domain family, member 3 -4.16255
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.0987
PCNA proliferating cell nuclear antigen -4.03645
USP19 ubiquitin specific peptidase 19 -3.8737
KIF15 kinesin family member 15 -3.8512
UBE3C ubiquitin protein ligase E3C -3.76675
FBXO5 F-box protein 5 -3.7096
GNPDA1 glucosamine-6-phosphate deaminase 1 -3.6957
CIRBP cold inducible RNA binding protein -3.68027
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -3.60615
TMEM176A transmembrane protein 176A -3.54805
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -3.35125
UNC50 unc-50 homolog (C. elegans) -3.34445
ZWINT ZW10 interacting kinetochore protein -3.28
ZDHHC6 zinc finger, DHHC-type containing 6 -3.27045
HMGB2 high mobility group box 2 -3.25085
REPIN1 replication initiator 1 -3.22385
C2CD5 C2 calcium-dependent domain containing 5 -3.2101
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.1991
DCK deoxycytidine kinase -3.194
CCNA2 cyclin A2 -3.18563
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.18505
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.17303
PRCP prolylcarboxypeptidase (angiotensinase C) -3.14815
DNM1 dynamin 1 -3.1429
SUOX sulfite oxidase -3.1276
KHDC4 KH domain containing 4, pre-mRNA splicing factor -3.0904
ACAD8 acyl-CoA dehydrogenase family, member 8 -3.09005
ZNF83 zinc finger protein 83 -3.08645
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.0826
CPNE3 copine III -3.07002
POT1 protection of telomeres 1 -3.04235
STMN1 stathmin 1 -3.0394
YEATS4 YEATS domain containing 4 -3.0364
THYN1 thymocyte nuclear protein 1 -3.0335
CISD1 CDGSH iron sulfur domain 1 -3.0134
E2F8 E2F transcription factor 8 -3.0115
HOXA4 homeobox A4 -2.9803
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.9734
EAPP E2F-associated phosphoprotein -2.96655
CCNB2 cyclin B2 -2.9603
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.95963
BAHCC1 BAH domain and coiled-coil containing 1 -2.9557
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.95375
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.9459
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.945
MPHOSPH9 M-phase phosphoprotein 9 -2.9189
TROAP trophinin associated protein -2.89275
H2AX H2A.X variant histone -2.89075
PLK1 polo-like kinase 1 -2.89005
NRIP1 nuclear receptor interacting protein 1 -2.87345
RALGDS ral guanine nucleotide dissociation stimulator -2.86795
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -2.8594
SNRPE small nuclear ribonucleoprotein polypeptide E -2.85515
HILPDA hypoxia inducible lipid droplet-associated -2.8444
TBC1D10C TBC1 domain family, member 10C -2.84055
OXA1L oxidase (cytochrome c) assembly 1-like -2.7925
EFNA3 ephrin-A3 -2.7817
MTA1 metastasis associated 1 -2.776
KIF4A kinesin family member 4A -2.7673
MIS18A MIS18 kinetochore protein A -2.76625
NCAPG2 non-SMC condensin II complex, subunit G2 -2.76545
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 -2.7562
LRPPRC leucine-rich pentatricopeptide repeat containing -2.75295
FASTK Fas-activated serine/threonine kinase -2.73657
BLCAP bladder cancer associated protein -2.73125
WDR5B WD repeat domain 5B -2.7042
TMEM176B transmembrane protein 176B -2.69985
LETMD1 LETM1 domain containing 1 -2.6891
PRUNE1 prune exopolyphosphatase 1 -2.67772
MGST2 microsomal glutathione S-transferase 2 -2.677
ZBED5 zinc finger, BED-type containing 5 -2.6754
PCLAF PCNA clamp associated factor -2.67368
CETN3 centrin, EF-hand protein, 3 -2.6519
DCXR dicarbonyl/L-xylulose reductase -2.6518
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -2.64852
CEP76 centrosomal protein 76kDa -2.64628
PSIP1 PC4 and SFRS1 interacting protein 1 -2.64428
PPA2 pyrophosphatase (inorganic) 2 -2.644
LBR lamin B receptor -2.62325
TTI1 TELO2 interacting protein 1 -2.61945
PRR15L proline rich 15-like -2.6181
INTS14 integrator complex subunit 14 -2.6079
RBM4B RNA binding motif protein 4B -2.6057
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -2.59895
TSFM Ts translation elongation factor, mitochondrial -2.59433
EFNA4 ephrin-A4 -2.58935
LDHD lactate dehydrogenase D -2.5882
RACGAP1 Rac GTPase activating protein 1 -2.58805
PIMREG PICALM interacting mitotic regulator -2.57415
PRMT3 protein arginine methyltransferase 3 -2.5682
HOXA10 homeobox A10 -2.55907
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.5568
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.55295
TRMT5 tRNA methyltransferase 5 -2.5511
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.5486
EIF3E eukaryotic translation initiation factor 3, subunit E -2.5377
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.526
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -2.52335
KIF18B kinesin family member 18B -2.5207
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.51615
CD58 CD58 molecule -2.51288
TMEM39B transmembrane protein 39B -2.50545
ACO1 aconitase 1, soluble -2.49755
TFB2M transcription factor B2, mitochondrial -2.4969
GTPBP8 GTP-binding protein 8 (putative) -2.49545
NNT nicotinamide nucleotide transhydrogenase -2.4949
HLTF helicase-like transcription factor -2.4909
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.4909
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -2.48528
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.48525
ZNF783 zinc finger family member 783 -2.47732
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.47335
SGK1 serum/glucocorticoid regulated kinase 1 -2.4663
PXMP4 peroxisomal membrane protein 4, 24kDa -2.4654
MACROD1 MACRO domain containing 1 -2.4645
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -2.46165
TMEM121 transmembrane protein 121 -2.45785
NAMPT nicotinamide phosphoribosyltransferase -2.45773
RANBP6 RAN binding protein 6 -2.4543
RPA3 replication protein A3, 14kDa -2.45145
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) -2.44755
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.44195
MELK maternal embryonic leucine zipper kinase -2.4395
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.4387
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.4355
NCAPD2 non-SMC condensin I complex, subunit D2 -2.43475
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.4322
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -2.43135
AHCY adenosylhomocysteinase -2.42635
TTC19 tetratricopeptide repeat domain 19 -2.41395
PGAP2 post-GPI attachment to proteins 2 -2.41365
TSPAN6 tetraspanin 6 -2.41175
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.41038
TSPAN12 tetraspanin 12 -2.40605
KDM1A lysine (K)-specific demethylase 1A -2.4045
COL3A1 collagen, type III, alpha 1 -2.39873
CDCA4 cell division cycle associated 4 -2.3966
TMEM168 transmembrane protein 168 -2.39085
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -2.3874
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.38562
RBL1 retinoblastoma-like 1 -2.37725
QARS1 glutaminyl-tRNA synthetase 1 -2.36795
LMNB1 lamin B1 -2.36665
PDGFRL platelet-derived growth factor receptor-like -2.36625
SMAD1 SMAD family member 1 -2.3609
FANCG Fanconi anemia, complementation group G -2.3539
NAT10 N-acetyltransferase 10 (GCN5-related) -2.35195
PLSCR1 phospholipid scramblase 1 -2.343
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -2.33455
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.3282
SLC38A6 solute carrier family 38, member 6 -2.32655
CCNF cyclin F -2.32512
METTL1 methyltransferase like 1 -2.3186
VRK1 vaccinia related kinase 1 -2.3185
TOMM70 translocase of outer mitochondrial membrane 70 -2.31822
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -2.3117
ACAA1 acetyl-CoA acyltransferase 1 -2.3059
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -2.3
FAM50B family with sequence similarity 50, member B -2.28595
TXNDC9 thioredoxin domain containing 9 -2.28113
NFIL3 nuclear factor, interleukin 3 regulated -2.27585
PUM2 pumilio RNA-binding family member 2 -2.27227
ADI1 acireductone dioxygenase 1 -2.2702
CREG1 cellular repressor of E1A-stimulated genes 1 -2.26995
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -2.26625
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.2653
PEX11B peroxisomal biogenesis factor 11 beta -2.2644
GRAMD4 GRAM domain containing 4 -2.2566
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -2.2543
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.2535
BET1 Bet1 golgi vesicular membrane trafficking protein -2.24855
DET1 de-etiolated homolog 1 (Arabidopsis) -2.24705
THTPA thiamine triphosphatase -2.24645
TTK TTK protein kinase -2.24595
TMEM135 transmembrane protein 135 -2.2396
CENPA centromere protein A -2.23742
TRMT61B tRNA methyltransferase 61B -2.2267
GFER growth factor, augmenter of liver regeneration -2.2219
LYRM1 LYR motif containing 1 -2.2104
RMI1 RecQ mediated genome instability 1 -2.20805
RNMT RNA (guanine-7-) methyltransferase -2.20393
ATRAID all-trans retinoic acid-induced differentiation factor -2.20295
LTN1 listerin E3 ubiquitin protein ligase 1 -2.201
NIPSNAP2 nipsnap homolog 2 -2.1867
CASC3 cancer susceptibility candidate 3 -2.1858
SRP54 signal recognition particle 54kDa -2.18485
DVL2 dishevelled segment polarity protein 2 -2.1807
ACTMAP actin maturation protease -2.1807
PGM1 phosphoglucomutase 1 -2.18045
TFAM transcription factor A, mitochondrial -2.18038
NABP2 nucleic acid binding protein 2 -2.18005
NUP88 nucleoporin 88kDa -2.1779
LACTB2 lactamase, beta 2 -2.17315
RBM39 RNA binding motif protein 39 -2.17005
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -2.1649
NCAPD3 non-SMC condensin II complex, subunit D3 -2.163
THOC6 THO complex 6 -2.16275
BANF1 barrier to autointegration factor 1 -2.1627
TM2D3 TM2 domain containing 3 -2.15995
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -2.15795
RPS5 ribosomal protein S5 -2.1572
HINFP histone H4 transcription factor -2.15675
ZNF175 zinc finger protein 175 -2.1552
SRBD1 S1 RNA binding domain 1 -2.15085
PCIF1 PDX1 C-terminal inhibiting factor 1 -2.14741
BCHE butyrylcholinesterase -2.1473
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.141
SIVA1 SIVA1, apoptosis-inducing factor -2.14083
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.13825
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.1354
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -2.1313
HOXC10 homeobox C10 -2.12745
CTDNEP1 CTD nuclear envelope phosphatase 1 -2.12515
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.1247
COG2 component of oligomeric golgi complex 2 -2.1217
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.1199
RFC3 replication factor C (activator 1) 3, 38kDa -2.11915
MEOX1 mesenchyme homeobox 1 -2.11165
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.11065
F13A1 coagulation factor XIII, A1 polypeptide -2.10525
TCEAL9 transcription elongation factor A like 9 -2.1042
CTNNA2 catenin (cadherin-associated protein), alpha 2 -2.1011
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.0932
GAMT guanidinoacetate N-methyltransferase -2.09295
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.0922
CCT8 chaperonin containing TCP1, subunit 8 (theta) -2.0921
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -2.09135
MPV17 MpV17 mitochondrial inner membrane protein -2.0903
NUP205 nucleoporin 205kDa -2.08855
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.0881
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.08577
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) -2.0837
EMX2 empty spiracles homeobox 2 -2.0831
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -2.07997
MKI67 marker of proliferation Ki-67 -2.07926
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -2.07123
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.07085
MBIP MAP3K12 binding inhibitory protein 1 -2.07075
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -2.06905
CRIPT cysteine-rich PDZ-binding protein -2.06855
QTRT1 queuine tRNA-ribosyltransferase 1 -2.0674
SCN3A sodium channel, voltage gated, type III alpha subunit -2.0655
ADNP activity-dependent neuroprotector homeobox -2.06265
POU2F1 POU class 2 homeobox 1 -2.06095
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein -2.05495
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.05275
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.04795
EPHB6 EPH receptor B6 -2.0476
ARF5 ADP-ribosylation factor 5 -2.04735
ZNF26 zinc finger protein 26 -2.0461
SLC25A38 solute carrier family 25, member 38 -2.04355
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.04305
OARD1 O-acyl-ADP-ribose deacylase 1 -2.0415
RBM14-RBM4 RBM14-RBM4 readthrough -2.03825
PROS1 protein S (alpha) -2.0367
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.03635
THAP12 THAP domain containing 12 -2.03615
GGCT gamma-glutamylcyclotransferase -2.03145
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.0286
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.02432
SPPL2A signal peptide peptidase like 2A -2.02395
MKKS McKusick-Kaufman syndrome -2.0233
RSL1D1 ribosomal L1 domain containing 1 -2.01678
PTCD3 pentatricopeptide repeat domain 3 -2.0166
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.01525
MTUS1 microtubule associated tumor suppressor 1 -2.01243
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.01128
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.0105
CDC23 cell division cycle 23 -2.0084
AAMP angio-associated, migratory cell protein -2.00735
CCDC47 coiled-coil domain containing 47 -2.0071
LYSET lysosomal enzyme trafficking factor -2.0064
SCAP SREBF chaperone -2.00465
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.00425
CKS1B CDC28 protein kinase regulatory subunit 1B -2.0034