CRCGN017_MCF10A.WT.HP_24H:E09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description rotenone 11.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

459 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WIF1 WNT inhibitory factor 1 6.2488
CXCL2 chemokine (C-X-C motif) ligand 2 5.96325
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 5.0998
H2BC12 H2B clustered histone 12 4.9931
TNIP1 TNFAIP3 interacting protein 1 4.44195
WASF3 WAS protein family, member 3 4.2654
STXBP1 syntaxin binding protein 1 4.2262
MYH9 myosin, heavy chain 9, non-muscle 4.19305
CAB39 calcium binding protein 39 3.9808
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.9546
PTPN1 protein tyrosine phosphatase, non-receptor type 1 3.7682
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.74535
SQOR sulfide quinone oxidoreductase 3.7282
BCAT1 branched chain amino-acid transaminase 1, cytosolic 3.5979
MICALL1 MICAL-like 1 3.59465
KCTD5 potassium channel tetramerization domain containing 5 3.41595
H2BC9 H2B clustered histone 9 3.3213
LRRC59 leucine rich repeat containing 59 3.21965
CEMIP2 cell migration inducing hyaluronidase 2 3.17855
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 3.14957
ACTN4 actinin, alpha 4 3.06075
RGS2 regulator of G-protein signaling 2 3.0384
PLEK2 pleckstrin 2 3.0346
TGFB1I1 transforming growth factor beta 1 induced transcript 1 3.0197
LOC122526780 uncharacterized LOC122526780 2.9463
FOSL1 FOS-like antigen 1 2.9262
CDCP1 CUB domain containing protein 1 2.92345
VAT1 vesicle amine transport 1 2.9192
CAV2 caveolin 2 2.91633
CTSZ cathepsin Z 2.91065
CDPF1 cysteine-rich, DPF motif domain containing 1 2.9095
DUSP14 dual specificity phosphatase 14 2.8945
SH2B3 SH2B adaptor protein 3 2.8517
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.8441
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.8305
COCH cochlin 2.82555
H2BC4 H2B clustered histone 4 2.82121
RALB v-ral simian leukemia viral oncogene homolog B 2.8155
SMAD3 SMAD family member 3 2.80424
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.804
ZYX zyxin 2.7815
DCTN1 dynactin 1 2.7807
LRP10 low density lipoprotein receptor-related protein 10 2.7473
UBE3C ubiquitin protein ligase E3C 2.74175
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.7358
TUBB2A tubulin, beta 2A class IIa 2.71169
WSB2 WD repeat and SOCS box containing 2 2.6935
CCND1 cyclin D1 2.69335
IL1A interleukin 1, alpha 2.6808
HBEGF heparin-binding EGF-like growth factor 2.67532
TICAM1 toll-like receptor adaptor molecule 1 2.6641
NCK2 NCK adaptor protein 2 2.6538
EHD4 EH-domain containing 4 2.6079
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 2.58397
MARK4 MAP/microtubule affinity-regulating kinase 4 2.58192
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 2.5669
DUSP4 dual specificity phosphatase 4 2.56642
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 2.55665
TRAF1 TNF receptor-associated factor 1 2.5488
TP53BP2 tumor protein p53 binding protein 2 2.54775
CYB5R3 cytochrome b5 reductase 3 2.5431
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.543
CXCL3 chemokine (C-X-C motif) ligand 3 2.54285
H2BC5 H2B clustered histone 5 2.5374
BAG3 BCL2-associated athanogene 3 2.5286
PLAUR plasminogen activator, urokinase receptor 2.52608
TOR4A torsin family 4, member A 2.52225
CXCL8 chemokine (C-X-C motif) ligand 8 2.5076
ARSJ arylsulfatase family, member J 2.5036
ZBED2 zinc finger, BED-type containing 2 2.5008
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 2.498
FBXO11 F-box protein 11 2.49503
DENND5B DENN/MADD domain containing 5B 2.49465
ATXN2 ataxin 2 2.4941
LAMC2 laminin, gamma 2 2.48935
CDR2L cerebellar degeneration-related protein 2-like 2.4845
F3 coagulation factor III (thromboplastin, tissue factor) 2.47745
ZNF23 zinc finger protein 23 2.46745
WDR45B WD repeat domain 45B 2.44435
SAV1 salvador family WW domain containing protein 1 2.44315
MVP major vault protein 2.4372
MYL9 myosin, light chain 9, regulatory 2.41845
H2AC19 H2A clustered histone 19 2.40847
XKR8 XK, Kell blood group complex subunit-related family, member 8 2.40555
TXNL4B thioredoxin-like 4B 2.40335
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.4
SAP30BP SAP30 binding protein 2.3968
NPC1 Niemann-Pick disease, type C1 2.39668
RNF11 ring finger protein 11 2.38955
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 2.38915
RTN4 reticulon 4 2.38322
PTBP2 polypyrimidine tract binding protein 2 2.382
ACLY ATP citrate lyase 2.37602
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.37236
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.3634
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.3622
HDLBP high density lipoprotein binding protein 2.34667
DRAM1 DNA-damage regulated autophagy modulator 1 2.3359
ZNF552 zinc finger protein 552 2.3354
IER3 immediate early response 3 2.33405
PLA2G15 phospholipase A2, group XV 2.3125
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.30515
LASP1 LIM and SH3 protein 1 2.2975
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 2.29249
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.2913
ESYT1 extended synaptotagmin-like protein 1 2.2743
CCN2 cellular communication network factor 2 2.2693
FHL2 four and a half LIM domains 2 2.2651
KLF7 Kruppel-like factor 7 (ubiquitous) 2.2591
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 2.25795
RIPOR1 RHO family interacting cell polarization regulator 1 2.24032
ANKRD40 ankyrin repeat domain 40 2.21795
ZNF426 zinc finger protein 426 2.2165
GRB14 growth factor receptor-bound protein 14 2.2128
TCL1A T-cell leukemia/lymphoma 1A 2.21072
IL1B interleukin 1, beta 2.20685
SLC35F2 solute carrier family 35, member F2 2.2016
EGR1 early growth response 1 2.19152
BBS7 Bardet-Biedl syndrome 7 2.18475
EPN2 epsin 2 2.18225
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.17945
ELOVL1 ELOVL fatty acid elongase 1 2.17863
STX1A syntaxin 1A (brain) 2.17495
RNF19B ring finger protein 19B 2.17285
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.16985
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.16055
NUCB2 nucleobindin 2 2.15465
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.1512
RBM6 RNA binding motif protein 6 2.1487
PYCR1 pyrroline-5-carboxylate reductase 1 2.1484
DHCR24 24-dehydrocholesterol reductase 2.1452
EXOSC10 exosome component 10 2.1444
DSG2 desmoglein 2 2.1444
WWC2 WW and C2 domain containing 2 2.13785
PTHLH parathyroid hormone-like hormone 2.13577
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 2.1349
KIF3B kinesin family member 3B 2.13385
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.13295
LSR lipolysis stimulated lipoprotein receptor 2.1326
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.13105
JMJD6 jumonji domain containing 6 2.13075
RPAP1 RNA polymerase II associated protein 1 2.12405
SMTN smoothelin 2.12195
MCUR1 mitochondrial calcium uniporter regulator 1 2.11585
MAMLD1 mastermind-like domain containing 1 2.1153
NOL7 nucleolar protein 7, 27kDa 2.11263
FGD6 FYVE, RhoGEF and PH domain containing 6 2.1084
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 2.1062
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.1034
ZNF165 zinc finger protein 165 2.10045
DYNLT3 dynein, light chain, Tctex-type 3 2.09525
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 2.0949
FYN FYN proto-oncogene, Src family tyrosine kinase 2.0932
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 2.08995
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.08225
MMP10 matrix metallopeptidase 10 2.07785
CLDN1 claudin 1 2.07235
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 2.0637
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.06285
SEC62 SEC62 homolog (S. cerevisiae) 2.05807
TJP1 tight junction protein 1 2.0569
CCDC59 coiled-coil domain containing 59 2.054
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 2.05137
TNIP2 TNFAIP3 interacting protein 2 2.05043
ZDHHC14 zinc finger, DHHC-type containing 14 2.04955
TGFA transforming growth factor, alpha 2.04927
SLC75A1 solute carrier family 75 member 1 2.04095
NTAN1 N-terminal asparagine amidase 2.04052
SCRIB scribbled planar cell polarity protein 2.0358
GARS1 glycyl-tRNA synthetase 1 2.035
AGO2 argonaute RISC catalytic component 2 2.03355
FRYL FRY-like 2.03275
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.0268
TMEM87A transmembrane protein 87A 2.02203
CTLA4 cytotoxic T-lymphocyte-associated protein 4 2.01495
CNN2 calponin 2 2.01455
RASAL2 RAS protein activator like 2 2.0077
GRB10 growth factor receptor-bound protein 10 2.00768
VEGFC vascular endothelial growth factor C 2.0064
AFF4 AF4/FMR2 family, member 4 2.00495
H1-2 H1.2 linker histone, cluster member 2.0046
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2.00343

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -10.0
CDK1 cyclin-dependent kinase 1 -8.24367
TOP2A topoisomerase (DNA) II alpha 170kDa -7.10273
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -6.0277
HMG20B high mobility group 20B -5.21978
CDK4 cyclin-dependent kinase 4 -5.21155
CDC25B cell division cycle 25B -5.05195
S100A8 S100 calcium binding protein A8 -5.0
SGK1 serum/glucocorticoid regulated kinase 1 -5.0
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.9553
PSRC1 proline/serine-rich coiled-coil 1 -4.814
RPIA ribose 5-phosphate isomerase A -4.6245
NUSAP1 nucleolar and spindle associated protein 1 -4.6219
DDIT4 DNA-damage-inducible transcript 4 -4.59795
CCNB1 cyclin B1 -4.5903
PEX11B peroxisomal biogenesis factor 11 beta -4.5168
TM9SF2 transmembrane 9 superfamily member 2 -4.29985
CREG1 cellular repressor of E1A-stimulated genes 1 -4.1203
HOXA5 homeobox A5 -4.0485
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.0257
EPHB6 EPH receptor B6 -3.7815
BAHCC1 BAH domain and coiled-coil containing 1 -3.75495
BOLA1 bolA family member 1 -3.72475
PCNA proliferating cell nuclear antigen -3.6827
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -3.5792
HADH hydroxyacyl-CoA dehydrogenase -3.57692
CIRBP cold inducible RNA binding protein -3.574
NLRP4 NLR family, pyrin domain containing 4 -3.5251
UNC50 unc-50 homolog (C. elegans) -3.49225
ATRAID all-trans retinoic acid-induced differentiation factor -3.489
FUZ fuzzy planar cell polarity protein -3.439
KIF11 kinesin family member 11 -3.4099
UBE2A ubiquitin-conjugating enzyme E2A -3.40245
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -3.32655
RAD51C RAD51 paralog C -3.32562
TIPRL TOR signaling pathway regulator -3.32315
AURKB aurora kinase B -3.28485
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.25605
USP19 ubiquitin specific peptidase 19 -3.2447
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.24435
ZWINT ZW10 interacting kinetochore protein -3.10735
CLTB clathrin, light chain B -3.09629
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.04525
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -3.0335
ZBED5 zinc finger, BED-type containing 5 -3.03345
MFF mitochondrial fission factor -2.99105
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -2.9749
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.9694
CD58 CD58 molecule -2.95413
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.9331
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.93275
NISCH nischarin -2.92285
TCEAL1 transcription elongation factor A (SII)-like 1 -2.9017
RACGAP1 Rac GTPase activating protein 1 -2.89155
PPA2 pyrophosphatase (inorganic) 2 -2.88185
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.85418
SPPL2A signal peptide peptidase like 2A -2.8357
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.77655
TOMM70 translocase of outer mitochondrial membrane 70 -2.77017
ANKRD49 ankyrin repeat domain 49 -2.7622
TMEM121 transmembrane protein 121 -2.73765
QTRT1 queuine tRNA-ribosyltransferase 1 -2.71365
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.7042
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -2.7036
FBXO34 F-box protein 34 -2.6991
CKS1B CDC28 protein kinase regulatory subunit 1B -2.69755
GMPR2 guanosine monophosphate reductase 2 -2.69325
KIF15 kinesin family member 15 -2.69195
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.68907
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -2.68418
TSC22D3 TSC22 domain family, member 3 -2.6666
EAPP E2F-associated phosphoprotein -2.66
THTPA thiamine triphosphatase -2.6575
GAMT guanidinoacetate N-methyltransferase -2.65595
HOXA10 homeobox A10 -2.63823
MRPS14 mitochondrial ribosomal protein S14 -2.63248
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.61445
TMEM126B transmembrane protein 126B -2.61175
KRI1 KRI1 homolog (S. cerevisiae) -2.6087
SOBP sine oculis binding protein homolog (Drosophila) -2.5985
TLE6 transducin-like enhancer of split 6 -2.5945
BLCAP bladder cancer associated protein -2.59375
NCAPD2 non-SMC condensin I complex, subunit D2 -2.59225
PGM1 phosphoglucomutase 1 -2.58005
METTL17 methyltransferase like 17 -2.5777
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.5769
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.56845
PRCP prolylcarboxypeptidase (angiotensinase C) -2.5598
RAB5IF RAB5 interacting factor -2.553
PRR15L proline rich 15-like -2.55265
ANKRD10 ankyrin repeat domain 10 -2.5465
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -2.54105
PCNP PEST proteolytic signal containing nuclear protein -2.5326
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.52795
CCNL2 cyclin L2 -2.5263
COL3A1 collagen, type III, alpha 1 -2.50893
SLC61A1 solute carrier family 61 member 1 -2.50405
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.50315
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.5002
ZDHHC13 zinc finger, DHHC-type containing 13 -2.4993
LTB4R leukotriene B4 receptor -2.49723
CISD1 CDGSH iron sulfur domain 1 -2.49595
SESN1 sestrin 1 -2.48855
PUS3 pseudouridylate synthase 3 -2.478
ING4 inhibitor of growth family, member 4 -2.465
ZNF688 zinc finger protein 688 -2.458
C2CD5 C2 calcium-dependent domain containing 5 -2.4514
EDN2 endothelin 2 -2.451
PITX3 paired-like homeodomain 3 -2.4493
CLTA clathrin, light chain A -2.44627
TFB2M transcription factor B2, mitochondrial -2.44565
MDH1 malate dehydrogenase 1, NAD (soluble) -2.4393
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.42795
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.41845
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.4138
TSPAN6 tetraspanin 6 -2.41115
TCF15 transcription factor 15 (basic helix-loop-helix) -2.40495
PNMA3 paraneoplastic Ma antigen 3 -2.4022
H2AX H2A.X variant histone -2.39945
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.39875
CDCA4 cell division cycle associated 4 -2.39645
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.395
PDCD1 programmed cell death 1 -2.3945
DNASE1L3 deoxyribonuclease I-like 3 -2.3942
OXA1L oxidase (cytochrome c) assembly 1-like -2.39345
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.3904
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 -2.382
CENPA centromere protein A -2.38075
SNX17 sorting nexin 17 -2.3801
EVX1 even-skipped homeobox 1 -2.3782
NXT1 nuclear transport factor 2-like export factor 1 -2.3778
CKAP2 cytoskeleton associated protein 2 -2.3695
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.3639
DNM1 dynamin 1 -2.35575
MELK maternal embryonic leucine zipper kinase -2.3511
NFIL3 nuclear factor, interleukin 3 regulated -2.35005
HMGB2 high mobility group box 2 -2.34445
SIVA1 SIVA1, apoptosis-inducing factor -2.34385
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.34298
ZBTB5 zinc finger and BTB domain containing 5 -2.34085
BARD1 BRCA1 associated RING domain 1 -2.3396
COL6A3 collagen, type VI, alpha 3 -2.33385
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -2.3331
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.3246
PDE1A phosphodiesterase 1A, calmodulin-dependent -2.3217
MAT2B methionine adenosyltransferase II, beta -2.31805
TOR3A torsin family 3, member A -2.315
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -2.3127
FAM53B family with sequence similarity 53, member B -2.3072
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B -2.3034
PALB2 partner and localizer of BRCA2 -2.3024
OSGEP O-sialoglycoprotein endopeptidase -2.29705
RNASE4 ribonuclease, RNase A family, 4 -2.29035
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -2.2891
CAPN3 calpain 3, (p94) -2.28777
PMVK phosphomevalonate kinase -2.28435
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -2.281
ZNF219 zinc finger protein 219 -2.27955
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.27953
NUP133 nucleoporin 133kDa -2.27295
LRRC17 leucine rich repeat containing 17 -2.27255
PRUNE1 prune exopolyphosphatase 1 -2.27208
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -2.2718
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.26835
PRR3 proline rich 3 -2.26465
GRK1 G protein-coupled receptor kinase 1 -2.26385
STK11 serine/threonine kinase 11 -2.2627
MPC2 mitochondrial pyruvate carrier 2 -2.26195
AP3M2 adaptor-related protein complex 3, mu 2 subunit -2.2611
ADI1 acireductone dioxygenase 1 -2.26025
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.2505
RCC1L RCC1 like -2.2486
USP39 ubiquitin specific peptidase 39 -2.2439
TRMT5 tRNA methyltransferase 5 -2.2409
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 -2.2388
ELP5 elongator acetyltransferase complex subunit 5 -2.2368
LDAF1 lipid droplet assembly factor 1 -2.2359
ASF1B anti-silencing function 1B histone chaperone -2.22735
CCNF cyclin F -2.22097
ARF5 ADP-ribosylation factor 5 -2.21495
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.21355
NTHL1 nth endonuclease III-like 1 (E. coli) -2.21335
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.21175
WDR73 WD repeat domain 73 -2.2102
HSPA1A heat shock 70kDa protein 1A -2.20975
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.2092
CARD8 caspase recruitment domain family, member 8 -2.1898
DUX4 double homeobox 4 -2.1886
ANG angiogenin, ribonuclease, RNase A family, 5 -2.1791
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.17855
CCNB2 cyclin B2 -2.176
TFAM transcription factor A, mitochondrial -2.17597
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.17465
LOC124900388 uncharacterized LOC124900388 -2.17105
FMOD fibromodulin -2.16955
GSPT2 G1 to S phase transition 2 -2.16625
CCNA2 cyclin A2 -2.16307
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.16205
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.1617
DBF4 DBF4 zinc finger -2.1579
GDF2 growth differentiation factor 2 -2.15505
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -2.15475
GRAMD4 GRAM domain containing 4 -2.1544
ARMCX5 armadillo repeat containing, X-linked 5 -2.1503
PBK PDZ binding kinase -2.14845
PGAM2 phosphoglycerate mutase 2 (muscle) -2.1474
COQ6 coenzyme Q6 monooxygenase -2.14315
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.1425
HMGN3 high mobility group nucleosomal binding domain 3 -2.14215
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -2.1401
KIF4A kinesin family member 4A -2.14005
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -2.13925
COMMD10 COMM domain containing 10 -2.13435
THYN1 thymocyte nuclear protein 1 -2.13385
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 -2.1319
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -2.12517
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -2.1229
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.1186
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.1178
GTPBP8 GTP-binding protein 8 (putative) -2.11475
TMPO thymopoietin -2.11473
FGL2 fibrinogen-like 2 -2.1126
CPZ carboxypeptidase Z -2.1121
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) -2.1102
TNNT3 troponin T type 3 (skeletal, fast) -2.1081
MAT2A methionine adenosyltransferase II, alpha -2.10665
CRBN cereblon -2.10665
SRSF8 serine/arginine-rich splicing factor 8 -2.10608
MEPCE methylphosphate capping enzyme -2.1006
KIFC1 kinesin family member C1 -2.0998
HMX1 H6 family homeobox 1 -2.09975
PCYOX1L prenylcysteine oxidase 1 like -2.09515
CXCR3 chemokine (C-X-C motif) receptor 3 -2.09468
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.0938
TMEM254 transmembrane protein 254 -2.0927
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.08873
TXNDC9 thioredoxin domain containing 9 -2.0865
IFT46 intraflagellar transport 46 -2.08515
CCDC169-SOHLH2 CCDC169-SOHLH2 readthrough -2.08305
PLK1 polo-like kinase 1 -2.0814
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.08125
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.0782
EXOC1 exocyst complex component 1 -2.0761
EIF1B eukaryotic translation initiation factor 1B -2.076
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.0742
SYP synaptophysin -2.0682
EPHB3 EPH receptor B3 -2.06645
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -2.06297
PRMT7 protein arginine methyltransferase 7 -2.0605
DCN decorin -2.05959
TSFM Ts translation elongation factor, mitochondrial -2.05568
CDC45 cell division cycle 45 -2.05555
PCBP3 poly(rC) binding protein 3 -2.05385
TROAP trophinin associated protein -2.05215
TRAT1 T cell receptor associated transmembrane adaptor 1 -2.052
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -2.0497
PUM2 pumilio RNA-binding family member 2 -2.0479
DUSP9 dual specificity phosphatase 9 -2.04775
NREP neuronal regeneration related protein -2.04503
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough -2.0449
ARL2 ADP-ribosylation factor-like 2 -2.0439
METTL4 methyltransferase like 4 -2.0435
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -2.04292
GOLGA7 golgin A7 -2.0424
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.0348
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 -2.03225
THAP12 THAP domain containing 12 -2.0313
MRPL46 mitochondrial ribosomal protein L46 -2.0297
RRAGA Ras-related GTP binding A -2.02865
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -2.0279
MGP matrix Gla protein -2.02685
MCRS1 microspherule protein 1 -2.0268
FBXO5 F-box protein 5 -2.02395
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.02185
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -2.01915
ARB2A ARB2 cotranscriptional regulator A -2.01305
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.00445