| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | emodin 5.61 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:E15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFB3 | transforming growth factor, beta 3 | 5.57035 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.4682 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 5.18825 |
| AGR2 | anterior gradient 2 | 5.07445 |
| CCP110 | centriolar coiled coil protein 110kDa | 5.0696 |
| OLFML2B | olfactomedin-like 2B | 4.9485 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.91015 |
| WIF1 | WNT inhibitory factor 1 | 3.81075 |
| TBPL1 | TBP-like 1 | 3.33005 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 3.25565 |
| RPL39L | ribosomal protein L39-like | 3.17475 |
| PLS1 | plastin 1 | 3.0866 |
| CDK19 | cyclin-dependent kinase 19 | 2.83757 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 2.53815 |
| PLIN1 | perilipin 1 | 2.51075 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 2.482 |
| RASL12 | RAS-like, family 12 | 2.39115 |
| ALDOC | aldolase C, fructose-bisphosphate | 2.37245 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 2.37195 |
| PCOLCE | procollagen C-endopeptidase enhancer | 2.3496 |
| STAMBP | STAM binding protein | 2.34645 |
| LPL | lipoprotein lipase | 2.29275 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.2919 |
| CHRDL1 | chordin-like 1 | 2.2741 |
| HILPDA | hypoxia inducible lipid droplet-associated | 2.26205 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 2.2096 |
| FABP4 | fatty acid binding protein 4, adipocyte | 2.1929 |
| KIZ | kizuna centrosomal protein | 2.15385 |
| FBXO7 | F-box protein 7 | 2.1492 |
| PAAF1 | proteasomal ATPase-associated factor 1 | 2.1383 |
| SUSD6 | sushi domain containing 6 | 2.11325 |
| NID2 | nidogen 2 (osteonidogen) | 2.09975 |
| POLR2M | polymerase (RNA) II (DNA directed) polypeptide M | 2.0593 |
| NEK3 | NIMA-related kinase 3 | 2.0498 |
| MYL9 | myosin, light chain 9, regulatory | 2.03715 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -8.30975 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -4.79685 |
| PGAM4 | phosphoglycerate mutase family member 4 | -4.7648 |
| YME1L1 | YME1-like 1 ATPase | -4.32638 |
| CD81 | CD81 molecule | -3.9579 |
| MSN | moesin | -3.8315 |
| WASHC4 | WASH complex subunit 4 | -3.6085 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -3.53998 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.37905 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | -3.16205 |
| EXOSC4 | exosome component 4 | -3.04782 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.9654 |
| SYNGR3 | synaptogyrin 3 | -2.73825 |
| KRT34 | keratin 34, type I | -2.7349 |
| PFN1 | profilin 1 | -2.6366 |
| MSMO1 | methylsterol monooxygenase 1 | -2.5204 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.51933 |
| FPGS | folylpolyglutamate synthase | -2.51375 |
| ABI1 | abl-interactor 1 | -2.42335 |
| UBTD1 | ubiquitin domain containing 1 | -2.34895 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -2.29665 |
| MT2A | metallothionein 2A | -2.16335 |
| VPREB1 | pre-B lymphocyte 1 | -2.12555 |
| KRT33A | keratin 33A, type I | -2.12385 |
| MTPAP | mitochondrial poly(A) polymerase | -2.1236 |
| SQSTM1 | sequestosome 1 | -2.10275 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | -2.07335 |
| KRTAP1-1 | keratin associated protein 1-1 | -2.06115 |
| SORBS1 | sorbin and SH3 domain containing 1 | -2.05305 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 | -2.047 |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 | -2.0167 |
| PITX2 | paired-like homeodomain 2 | -2.0019 |
