CRCGN017_MCF10A.WT.HP_24H:E16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tetrakis(hydroxymethyl)phos-phonium chloride 101.47 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

1027 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:E16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUCB2 nucleobindin 2 10.0
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 7.57335
TXNRD1 thioredoxin reductase 1 7.1871
LRP10 low density lipoprotein receptor-related protein 10 7.0462
GLRX glutaredoxin (thioltransferase) 6.94978
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.3304
HBB hemoglobin, beta 6.259
HBA1 hemoglobin, alpha 1 6.14348
SQSTM1 sequestosome 1 6.1339
ABHD4 abhydrolase domain containing 4 5.9723
CDPF1 cysteine-rich, DPF motif domain containing 1 5.89215
ADGRE5 adhesion G protein-coupled receptor E5 5.68855
KLHL21 kelch-like family member 21 5.475
WFS1 Wolfram syndrome 1 (wolframin) 5.45795
RAP1GAP RAP1 GTPase activating protein 5.29415
MVP major vault protein 5.0092
SLC35B1 solute carrier family 35, member B1 4.79405
TNIP1 TNFAIP3 interacting protein 1 4.7166
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 4.61548
SPAG4 sperm associated antigen 4 4.5383
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 4.4825
DHRS7 dehydrogenase/reductase (SDR family) member 7 4.319
HMOX1 heme oxygenase 1 4.2826
CNRIP1 cannabinoid receptor interacting protein 1 4.19545
FOXO4 forkhead box O4 4.1618
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 4.1412
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 4.08225
SLC67A1 solute carrier family 67 member 1 4.04705
CRELD2 cysteine-rich with EGF-like domains 2 3.99715
MANF mesencephalic astrocyte-derived neurotrophic factor 3.9102
CLTC clathrin, heavy chain (Hc) 3.8729
TM9SF2 transmembrane 9 superfamily member 2 3.86305
CXCL2 chemokine (C-X-C motif) ligand 2 3.84535
RPN1 ribophorin I 3.83995
FHL2 four and a half LIM domains 2 3.83275
LOXL1 lysyl oxidase-like 1 3.8302
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 3.7987
PGRMC1 progesterone receptor membrane component 1 3.76615
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 3.7521
TM9SF3 transmembrane 9 superfamily member 3 3.71225
CYB5R1 cytochrome b5 reductase 1 3.70965
TMEM50A transmembrane protein 50A 3.69185
HYOU1 hypoxia up-regulated 1 3.6888
IGHMBP2 immunoglobulin mu binding protein 2 3.6714
LOC114841035 uncharacterized LOC114841035 3.64995
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.62435
VAT1 vesicle amine transport 1 3.622
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 3.6145
TRIM16 tripartite motif containing 16 3.53645
DUSP14 dual specificity phosphatase 14 3.5334
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.51925
AFTPH aftiphilin 3.50235
DYNLT3 dynein, light chain, Tctex-type 3 3.50235
TJP1 tight junction protein 1 3.4823
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 3.46115
TMEM59 transmembrane protein 59 3.4509
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 3.44925
MYH9 myosin, heavy chain 9, non-muscle 3.42765
TERF2IP telomeric repeat binding factor 2, interacting protein 3.427
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 3.37497
PRSS8 protease, serine, 8 3.36915
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 3.36145
ZC3H12A zinc finger CCCH-type containing 12A 3.3583
GPX2 glutathione peroxidase 2 3.35355
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 3.3382
GFPT1 glutamine--fructose-6-phosphate transaminase 1 3.33598
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 3.3334
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 3.3253
SMAD3 SMAD family member 3 3.32308
CTSA cathepsin A 3.31155
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3.2829
CALCOCO1 calcium binding and coiled-coil domain 1 3.24835
EMC3 ER membrane protein complex subunit 3 3.2297
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.22365
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 3.1954
SMIM40 small integral membrane protein 40 3.1918
AGR2 anterior gradient 2 3.1882
YPEL5 yippee-like 5 (Drosophila) 3.154
APOD apolipoprotein D 3.14645
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.14567
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.1333
GABARAPL1 GABA(A) receptor-associated protein like 1 3.12252
TUFT1 tuftelin 1 3.1016
DES desmin 3.0999
LAPTM4A lysosomal protein transmembrane 4 alpha 3.09705
STAP2 signal transducing adaptor family member 2 3.05585
CTSL cathepsin L 3.04795
SDC4 syndecan 4 3.0419
NFE2L1 nuclear factor, erythroid 2-like 1 3.02872
UBE2H ubiquitin-conjugating enzyme E2H 3.01673
MCUR1 mitochondrial calcium uniporter regulator 1 3.01095
KEAP1 kelch-like ECH-associated protein 1 2.98735
LMTK1 lemur tail kinase 1 2.981
WDTC1 WD and tetratricopeptide repeats 1 2.97363
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.97175
ATP9A ATPase, class II, type 9A 2.9516
PLA2G15 phospholipase A2, group XV 2.94515
TMEM127 transmembrane protein 127 2.93815
MINDY1 MINDY lysine 48 deubiquitinase 1 2.93425
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.93205
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 2.92265
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.91975
BABAM2 BRISC and BRCA1 A complex member 2 2.9181
ZMAT3 zinc finger, matrin-type 3 2.91575
BCL2L2 BCL2-like 2 2.91385
TSG101 tumor susceptibility 101 2.8979
COQ8A coenzyme Q8A 2.89085
ABLIM3 actin binding LIM protein family, member 3 2.8888
STX4 syntaxin 4 2.88845
NCSTN nicastrin 2.8869
SPATA2L spermatogenesis associated 2-like 2.87235
CANT1 calcium activated nucleotidase 1 2.87178
RBKS ribokinase 2.86947
IRS1 insulin receptor substrate 1 2.8677
SYNE2 spectrin repeat containing, nuclear envelope 2 2.86115
PGPEP1 pyroglutamyl-peptidase I 2.8574
AHNAK2 AHNAK nucleoprotein 2 2.84835
SARAF store-operated calcium entry-associated regulatory factor 2.84645
DGKD diacylglycerol kinase, delta 130kDa 2.84325
SMIM10L1 small integral membrane protein 10 like 1 2.84195
EPHA2 EPH receptor A2 2.83535
STIM1 stromal interaction molecule 1 2.82755
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.8261
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.825
CTF1 cardiotrophin 1 2.81925
STXBP1 syntaxin binding protein 1 2.8157
PLPP2 phospholipid phosphatase 2 2.8067
LCMT1 leucine carboxyl methyltransferase 1 2.80655
AKR1C3 aldo-keto reductase family 1, member C3 2.7802
F3 coagulation factor III (thromboplastin, tissue factor) 2.76095
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.7604
RIOK3 RIO kinase 3 2.75317
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.74823
MGLL monoglyceride lipase 2.7448
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.7427
DSG2 desmoglein 2 2.736
TICAM1 toll-like receptor adaptor molecule 1 2.7212
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.72105
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.71935
CSNK1A1 casein kinase 1, alpha 1 2.71467
SCRN1 secernin 1 2.7134
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.7105
SERINC3 serine incorporator 3 2.70164
PDGFD platelet derived growth factor D 2.70105
TMEM94 transmembrane protein 94 2.7005
STN1 STN1 subunit of CST complex 2.69905
ITPKC inositol-trisphosphate 3-kinase C 2.69505
CEMIP2 cell migration inducing hyaluronidase 2 2.6876
MNT MAX network transcriptional repressor 2.6811
ZBTB22 zinc finger and BTB domain containing 22 2.67535
EMC7 ER membrane protein complex subunit 7 2.67165
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.6691
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 2.66635
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.6649
TMEM41B transmembrane protein 41B 2.66463
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.66135
CTSW cathepsin W 2.6595
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.65145
CRELD1 cysteine-rich with EGF-like domains 1 2.6509
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.64727
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 2.64035
HSPB8 heat shock 22kDa protein 8 2.64
GPSM3 G-protein signaling modulator 3 2.6352
FYN FYN proto-oncogene, Src family tyrosine kinase 2.58423
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2.57885
OPTN optineurin 2.5758
ATOSB atos homolog B 2.5746
AKR1C1 aldo-keto reductase family 1, member C1 2.57347
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.56023
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 2.5578
KIZ kizuna centrosomal protein 2.5565
HELZ helicase with zinc finger 2.5525
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 2.55105
AHNAK AHNAK nucleoprotein 2.54513
DUSP4 dual specificity phosphatase 4 2.53818
EHD1 EH-domain containing 1 2.53812
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.52321
ERMP1 endoplasmic reticulum metallopeptidase 1 2.5175
PANX1 pannexin 1 2.50865
MAP1B microtubule-associated protein 1B 2.50715
H2BC21 H2B clustered histone 21 2.5045
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.4995
FLRT2 fibronectin leucine rich transmembrane protein 2 2.4988
MUC13 mucin 13, cell surface associated 2.4972
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.49682
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.4965
DERL2 derlin 2 2.4935
TMEM40 transmembrane protein 40 2.4933
WIF1 WNT inhibitory factor 1 2.49105
SAA2 serum amyloid A2 2.48432
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.4829
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.48185
ACYP2 acylphosphatase 2, muscle type 2.4791
CLN3 ceroid-lipofuscinosis, neuronal 3 2.47827
CCPG1 cell cycle progression 1 2.47545
ARID5A AT rich interactive domain 5A (MRF1-like) 2.4726
DDA1 DET1 and DDB1 associated 1 2.4696
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 2.46935
KIF3C kinesin family member 3C 2.4691
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.465
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.4627
TIMP2 TIMP metallopeptidase inhibitor 2 2.46185
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.4579
UBE2A ubiquitin-conjugating enzyme E2A 2.45662
KIF13B kinesin family member 13B 2.45605
LGALS8 lectin, galactoside-binding, soluble, 8 2.43482
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 2.4344
ILK integrin-linked kinase 2.4336
TNF tumor necrosis factor 2.4313
DCTN1 dynactin 1 2.42788
AGBL5 ATP/GTP binding protein-like 5 2.4261
ELMO2 engulfment and cell motility 2 2.42525
PKP1 plakophilin 1 2.41773
BECN1 beclin 1, autophagy related 2.41622
XK X-linked Kx blood group 2.409
TP53I3 tumor protein p53 inducible protein 3 2.4038
H2BC12 H2B clustered histone 12 2.39418
EI24 etoposide induced 2.4 2.3887
BDKRB2 bradykinin receptor B2 2.3863
APH1B APH1B gamma secretase subunit 2.38575
DOK7 docking protein 7 2.38328
AGPS alkylglycerone phosphate synthase 2.3725
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.3709
PYGB phosphorylase, glycogen; brain 2.3643
MXRA7 matrix-remodelling associated 7 2.3626
CNN1 calponin 1, basic, smooth muscle 2.3551
LMNA lamin A/C 2.3515
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 2.35035
MISP mitotic spindle positioning 2.34895
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 2.34585
CCND3 cyclin D3 2.34045
PERP PERP, TP53 apoptosis effector 2.3367
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 2.33632
SIL1 SIL1 nucleotide exchange factor 2.33495
SFXN3 sideroflexin 3 2.33437
HDLBP high density lipoprotein binding protein 2.3333
SNX15 sorting nexin 15 2.3316
IRGQ immunity-related GTPase family, Q 2.3306
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 2.3299
IDS iduronate 2-sulfatase 2.32695
PTTG1IP pituitary tumor-transforming 1 interacting protein 2.32535
TMEM134 transmembrane protein 134 2.32305
WBP1L WW domain binding protein 1-like 2.3196
TALDO1 transaldolase 1 2.31935
PHKB phosphorylase kinase, beta 2.3158
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 2.31203
CYB5R3 cytochrome b5 reductase 3 2.3118
ERN2 endoplasmic reticulum to nucleus signaling 2 2.29675
STC1 stanniocalcin 1 2.29658
PHF21A PHD finger protein 21A 2.2959
METRN meteorin, glial cell differentiation regulator 2.29555
JUP junction plakoglobin 2.2935
ELL2 elongation factor, RNA polymerase II, 2 2.29255
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.28943
SH3BGRL SH3 domain binding glutamate-rich protein like 2.28733
TCEA2 transcription elongation factor A (SII), 2 2.28285
TMCO1 transmembrane and coiled-coil domains 1 2.2801
MFSD1 major facilitator superfamily domain containing 1 2.27965
EPB41L1 erythrocyte membrane protein band 4.1-like 1 2.27383
EFNB1 ephrin-B1 2.27205
SQOR sulfide quinone oxidoreductase 2.2668
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 2.26655
ARHGAP17 Rho GTPase activating protein 17 2.26515
TSPAN8 tetraspanin 8 2.26285
FAM114A1 family with sequence similarity 114, member A1 2.2582
PCBP3 poly(rC) binding protein 3 2.25675
DSTN destrin (actin depolymerizing factor) 2.25402
ADAP1 ArfGAP with dual PH domains 1 2.25198
IST1 increased sodium tolerance 1 homolog (yeast) 2.2512
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.24925
ADAM17 ADAM metallopeptidase domain 17 2.24873
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.24853
ZNF536 zinc finger protein 536 2.2453
CHMP4B charged multivesicular body protein 4B 2.2451
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.24365
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.24
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.23735
TBC1D22A TBC1 domain family, member 22A 2.23682
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 2.23557
BCAS4 breast carcinoma amplified sequence 4 2.23545
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.2342
ENO2 enolase 2 (gamma, neuronal) 2.2331
CES1 carboxylesterase 1 2.2326
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 2.22965
INF2 inverted formin, FH2 and WH2 domain containing 2.22895
CHMP1B charged multivesicular body protein 1B 2.22855
SCPEP1 serine carboxypeptidase 1 2.2283
F11R F11 receptor 2.22272
KRT16 keratin 16, type I 2.2214
RNF122 ring finger protein 122 2.2188
POC1B-GALNT4 POC1B-GALNT4 readthrough 2.21505
COPG1 coatomer protein complex, subunit gamma 1 2.21495
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 2.2117
RAB8A RAB8A, member RAS oncogene family 2.21135
IQCC IQ motif containing C 2.20985
STX5 syntaxin 5 2.2068
KDM6B lysine (K)-specific demethylase 6B 2.20542
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.20045
CTSV cathepsin V 2.1994
TMEM43 transmembrane protein 43 2.19595
EBI3 Epstein-Barr virus induced 3 2.1952
MAPK3 mitogen-activated protein kinase 3 2.19485
OSTM1 osteopetrosis associated transmembrane protein 1 2.19215
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.19115
ATP5F1E ATP synthase F1 subunit epsilon 2.19075
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.19075
LPAR2 lysophosphatidic acid receptor 2 2.18738
BIRC3 baculoviral IAP repeat containing 3 2.1801
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.17825
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.17665
GCLC glutamate-cysteine ligase, catalytic subunit 2.1721
EIF3G eukaryotic translation initiation factor 3, subunit G 2.1696
PLCB4 phospholipase C, beta 4 2.1661
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.166
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.1629
RBM15B RNA binding motif protein 15B 2.1604
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.15473
JAG1 jagged 1 2.15276
RABEP2 rabaptin, RAB GTPase binding effector protein 2 2.15072
MARK4 MAP/microtubule affinity-regulating kinase 4 2.14845
ALG12 ALG12, alpha-1,6-mannosyltransferase 2.14795
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.14745
UFM1 ubiquitin-fold modifier 1 2.1458
NUPR1 nuclear protein, transcriptional regulator, 1 2.1438
CES2 carboxylesterase 2 2.14277
SKIC2 SKI2 subunit of superkiller complex 2.14015
DUSP8 dual specificity phosphatase 8 2.1392
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 2.1385
KRT6B keratin 6B, type II 2.13695
ARMCX3 armadillo repeat containing, X-linked 3 2.13495
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.13417
CNKSR3 CNKSR family member 3 2.13215
RAB5B RAB5B, member RAS oncogene family 2.13115
EIF4A2 eukaryotic translation initiation factor 4A2 2.129
SFRP5 secreted frizzled-related protein 5 2.12765
ENAH enabled homolog (Drosophila) 2.12355
SYNC syncoilin, intermediate filament protein 2.12335
JARID2 jumonji, AT rich interactive domain 2 2.1219
PTHLH parathyroid hormone-like hormone 2.12037
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 2.11695
SLCO3A1 solute carrier organic anion transporter family, member 3A1 2.11608
CST4 cystatin S 2.11275
PLK3 polo-like kinase 3 2.1075
IGF2R insulin-like growth factor 2 receptor 2.10567
TXNDC15 thioredoxin domain containing 15 2.1033
ESYT1 extended synaptotagmin-like protein 1 2.10265
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.10195
CPT1A carnitine palmitoyltransferase 1A (liver) 2.10165
PCSK7 proprotein convertase subtilisin/kexin type 7 2.10075
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.10025
STXBP2 syntaxin binding protein 2 2.1001
SPRR1B small proline-rich protein 1B 2.09525
FOLR2 folate receptor 2 (fetal) 2.09515
BCORL1 BCL6 corepressor-like 1 2.09455
TMEM248 transmembrane protein 248 2.0929
DHRS1 dehydrogenase/reductase (SDR family) member 1 2.0929
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 2.09285
BLVRB biliverdin reductase B 2.0913
PI3 peptidase inhibitor 3, skin-derived 2.08973
FOSL2 FOS-like antigen 2 2.08937
RPN2 ribophorin II 2.08917
ZCCHC24 zinc finger, CCHC domain containing 24 2.08888
KRT6A keratin 6A, type II 2.0868
EDN1 endothelin 1 2.08645
RAB8B RAB8B, member RAS oncogene family 2.08605
RAB5IF RAB5 interacting factor 2.08355
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.0822
AQP5 aquaporin 5 2.0807
DENND4A DENN/MADD domain containing 4A 2.08015
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2.08
TM4SF1 transmembrane 4 L six family member 1 2.07874
KLC1 kinesin light chain 1 2.07675
RAB1A RAB1A, member RAS oncogene family 2.07447
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 2.07197
LGALS9C lectin, galactoside-binding, soluble, 9C 2.0714
H2AC6 H2A clustered histone 6 2.06855
PABPC3 poly(A) binding protein, cytoplasmic 3 2.0636
FBN2 fibrillin 2 2.06275
GPC1 glypican 1 2.054
KLRC4-KLRK1 KLRC4-KLRK1 readthrough 2.053
PDLIM1 PDZ and LIM domain 1 2.0523
ATG4A autophagy related 4A, cysteine peptidase 2.05125
APOL2 apolipoprotein L, 2 2.04905
GASK1B golgi associated kinase 1B 2.0479
MAGED2 melanoma antigen family D2 2.0463
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.0458
CAMTA2 calmodulin binding transcription activator 2 2.04465
ACTC1 actin, alpha, cardiac muscle 1 2.0436
INSR insulin receptor 2.0434
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 2.04265
NQO1 NAD(P)H dehydrogenase, quinone 1 2.04132
FAT4 FAT atypical cadherin 4 2.03315
RETREG1 reticulophagy regulator 1 2.03267
NIT1 nitrilase 1 2.03255
WDR26 WD repeat domain 26 2.0313
CCDC92 coiled-coil domain containing 92 2.03105
FKBP6 FK506 binding protein 6, 36kDa 2.0295
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 2.0284
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 2.0282
PRB2 proline-rich protein BstNI subfamily 2 2.02805
DDRGK1 DDRGK domain containing 1 2.0271
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.02455
RETREG2 reticulophagy regulator family member 2 2.01981
LIF leukemia inhibitory factor 2.0166
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 2.01515
PDIA6 protein disulfide isomerase family A, member 6 2.01486
DSG3 desmoglein 3 2.01395
EFCAB14 EF-hand calcium binding domain 14 2.01222
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) 2.00865
POPDC3 popeye domain containing 3 2.008
ZFAND3 zinc finger, AN1-type domain 3 2.008
FBXO2 F-box protein 2 2.00715
BLCAP bladder cancer associated protein 2.0066
TMED7 transmembrane emp24 protein transport domain containing 7 2.005
INPPL1 inositol polyphosphate phosphatase-like 1 2.00195
NRIP2 nuclear receptor interacting protein 2 2.001
TMEM184B transmembrane protein 184B 2.0004

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -10.0
PSRC1 proline/serine-rich coiled-coil 1 -9.34765
UBE2C ubiquitin-conjugating enzyme E2C -8.8625
CCNB2 cyclin B2 -8.77815
KIF20A kinesin family member 20A -8.3765
PLK1 polo-like kinase 1 -7.85655
TRAP1 TNF receptor-associated protein 1 -7.6361
CCNA2 cyclin A2 -7.37535
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -7.369
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -7.34965
DCK deoxycytidine kinase -7.25945
KIF14 kinesin family member 14 -7.02785
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -6.9068
C1QBP complement component 1, q subcomponent binding protein -6.8385
CDK1 cyclin-dependent kinase 1 -6.6497
MRPS2 mitochondrial ribosomal protein S2 -6.47495
CDC45 cell division cycle 45 -6.3918
CDCA8 cell division cycle associated 8 -6.1546
TOP2A topoisomerase (DNA) II alpha 170kDa -6.12455
PCNA proliferating cell nuclear antigen -5.88475
FBXO5 F-box protein 5 -5.7613
CD320 CD320 molecule -5.6374
AURKB aurora kinase B -5.5666
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -5.54815
BIRC5 baculoviral IAP repeat containing 5 -5.45638
ERCC6L excision repair cross-complementation group 6-like -5.39695
KIF11 kinesin family member 11 -5.277
STMN1 stathmin 1 -5.27195
LBR lamin B receptor -5.1834
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -5.1635
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -5.1463
CENPA centromere protein A -5.14112
EXO1 exonuclease 1 -5.08945
MCM6 minichromosome maintenance complex component 6 -5.084
KIF15 kinesin family member 15 -5.0805
DEPDC1 DEP domain containing 1 -4.95795
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -4.95043
ABHD10 abhydrolase domain containing 10 -4.9235
HJURP Holliday junction recognition protein -4.8994
MCM10 minichromosome maintenance complex component 10 -4.88
NCAPH non-SMC condensin I complex, subunit H -4.8756
CDT1 chromatin licensing and DNA replication factor 1 -4.8753
TTK TTK protein kinase -4.82065
ASF1B anti-silencing function 1B histone chaperone -4.7782
SPC25 SPC25, NDC80 kinetochore complex component -4.77265
KIF23 kinesin family member 23 -4.69245
NUP85 nucleoporin 85kDa -4.6351
SKA1 spindle and kinetochore associated complex subunit 1 -4.63115
ACOT9 acyl-CoA thioesterase 9 -4.6222
GINS2 GINS complex subunit 2 (Psf2 homolog) -4.6098
SCYL3 SCY1-like 3 (S. cerevisiae) -4.60112
PBK PDZ binding kinase -4.5983
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -4.57895
HMMR hyaluronan-mediated motility receptor (RHAMM) -4.57845
RFC3 replication factor C (activator 1) 3, 38kDa -4.57765
NEK2 NIMA-related kinase 2 -4.57127
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.54395
TROAP trophinin associated protein -4.54
ARID4B AT rich interactive domain 4B (RBP1-like) -4.5286
TRIP13 thyroid hormone receptor interactor 13 -4.5227
KIF4A kinesin family member 4A -4.47465
DBF4 DBF4 zinc finger -4.43895
VRK1 vaccinia related kinase 1 -4.4298
CDC6 cell division cycle 6 -4.41803
OIP5 Opa interacting protein 5 -4.41085
SPAG5 sperm associated antigen 5 -4.4086
MCM5 minichromosome maintenance complex component 5 -4.40035
TMPO thymopoietin -4.3896
HADH hydroxyacyl-CoA dehydrogenase -4.38067
NUSAP1 nucleolar and spindle associated protein 1 -4.36185
CHAF1B chromatin assembly factor 1, subunit B (p60) -4.34755
CCNF cyclin F -4.33903
PARP2 poly (ADP-ribose) polymerase 2 -4.32555
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -4.3085
KIF18A kinesin family member 18A -4.2947
CCNB1 cyclin B1 -4.28145
CEP55 centrosomal protein 55kDa -4.22055
CDK4 cyclin-dependent kinase 4 -4.21375
SPDL1 spindle apparatus coiled-coil protein 1 -4.20505
FIRRM FIGNL1 interacting regulator of recombination and mitosis -4.20345
KIF18B kinesin family member 18B -4.202
PRC1 protein regulator of cytokinesis 1 -4.188
FOXM1 forkhead box M1 -4.1816
ATAD2 ATPase family, AAA domain containing 2 -4.16965
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -4.1509
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.1465
MRPL19 mitochondrial ribosomal protein L19 -4.13225
PTCD3 pentatricopeptide repeat domain 3 -4.10625
MCM7 minichromosome maintenance complex component 7 -4.1014
ACOD1 aconitate decarboxylase 1 -4.09965
FABP5 fatty acid binding protein 5 (psoriasis-associated) -4.09045
RACGAP1 Rac GTPase activating protein 1 -4.08405
SMC1A structural maintenance of chromosomes 1A -4.05058
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.03205
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -4.02787
DNM1 dynamin 1 -4.02365
SLC35F2 solute carrier family 35, member F2 -3.9932
NUP93 nucleoporin 93kDa -3.98675
AURKA aurora kinase A -3.97857
RFWD3 ring finger and WD repeat domain 3 -3.97665
ENTR1 endosome associated trafficking regulator 1 -3.9429
MKI67 marker of proliferation Ki-67 -3.9422
HMGB2 high mobility group box 2 -3.9409
MCMBP minichromosome maintenance complex binding protein -3.9328
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -3.9227
NCAPG2 non-SMC condensin II complex, subunit G2 -3.9221
PARPBP PARP1 binding protein -3.91005
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.90555
BORA bora, aurora kinase A activator -3.898
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.89215
CDCA3 cell division cycle associated 3 -3.89055
TK1 thymidine kinase 1, soluble -3.883
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -3.8787
MCM3 minichromosome maintenance complex component 3 -3.862
CYCS cytochrome c, somatic -3.85755
NUP205 nucleoporin 205kDa -3.83835
CHEK1 checkpoint kinase 1 -3.82238
PIMREG PICALM interacting mitotic regulator -3.8051
UNG uracil-DNA glycosylase -3.79805
CENPN centromere protein N -3.78885
YEATS4 YEATS domain containing 4 -3.7745
ZMYM1 zinc finger, MYM-type 1 -3.76825
CDC25C cell division cycle 25C -3.75187
LMNB1 lamin B1 -3.7431
BOLA1 bolA family member 1 -3.738
TIPIN TIMELESS interacting protein -3.7235
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -3.7175
PLK4 polo-like kinase 4 -3.71223
SNRPA small nuclear ribonucleoprotein polypeptide A -3.7112
PUS1 pseudouridylate synthase 1 -3.69595
THOP1 thimet oligopeptidase 1 -3.6935
TRAPPC3 trafficking protein particle complex 3 -3.68498
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -3.677
SMNDC1 survival motor neuron domain containing 1 -3.646
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.6016
PRPF4 pre-mRNA processing factor 4 -3.60038
CDK2 cyclin-dependent kinase 2 -3.58162
DSN1 DSN1, MIS12 kinetochore complex component -3.56325
HAUS7 HAUS augmin-like complex, subunit 7 -3.56075
FXN frataxin -3.55225
CASP8AP2 caspase 8 associated protein 2 -3.5159
NCAPD2 non-SMC condensin I complex, subunit D2 -3.5101
NCAPD3 non-SMC condensin II complex, subunit D3 -3.50825
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -3.4917
DONSON downstream neighbor of SON -3.47775
TPX2 TPX2, microtubule-associated -3.47315
ZDHHC6 zinc finger, DHHC-type containing 6 -3.46545
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.4637
RUVBL1 RuvB-like AAA ATPase 1 -3.45835
UBE2S ubiquitin-conjugating enzyme E2S -3.44125
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.4412
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.4362
MPHOSPH9 M-phase phosphoprotein 9 -3.43335
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -3.42525
DTYMK deoxythymidylate kinase (thymidylate kinase) -3.40705
CETN3 centrin, EF-hand protein, 3 -3.4004
CBX3 chromobox homolog 3 -3.3941
RPIA ribose 5-phosphate isomerase A -3.3808
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.3806
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -3.354
BRCA1 breast cancer 1, early onset -3.35367
CKS2 CDC28 protein kinase regulatory subunit 2 -3.34535
CKS1B CDC28 protein kinase regulatory subunit 1B -3.3308
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.32905
FEN1 flap structure-specific endonuclease 1 -3.32845
DSCC1 DNA replication and sister chromatid cohesion 1 -3.30765
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -3.30595
NUP107 nucleoporin 107kDa -3.2896
CENPE centromere protein E, 312kDa -3.2846
KNTC1 kinetochore associated 1 -3.28215
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.28122
SHCBP1 SHC SH2-domain binding protein 1 -3.26635
TBP TATA box binding protein -3.2658
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -3.25545
FANCI Fanconi anemia, complementation group I -3.23898
E2F8 E2F transcription factor 8 -3.23385
CPAP centrosome assembly and centriole elongation protein -3.2026
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -3.2012
ZWILCH zwilch kinetochore protein -3.1928
ACYP1 acylphosphatase 1, erythrocyte (common) type -3.1853
RMI1 RecQ mediated genome instability 1 -3.17145
DNA2 DNA replication helicase/nuclease 2 -3.16925
KIF22 kinesin family member 22 -3.1617
SUMF2 sulfatase modifying factor 2 -3.16105
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -3.15585
RABEPK Rab9 effector protein with kelch motifs -3.1248
SETMAR SET domain and mariner transposase fusion gene -3.1196
MCM4 minichromosome maintenance complex component 4 -3.11579
GTPBP6 GTP binding protein 6 (putative) -3.10995
POLE polymerase (DNA directed), epsilon, catalytic subunit -3.1076
UXT ubiquitously-expressed, prefoldin-like chaperone -3.10558
RPA3 replication protein A3, 14kDa -3.10295
TACC3 transforming, acidic coiled-coil containing protein 3 -3.09155
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -3.08755
MRPL16 mitochondrial ribosomal protein L16 -3.08675
KIF20B kinesin family member 20B -3.08585
RFC2 replication factor C (activator 1) 2, 40kDa -3.08463
DHFR dihydrofolate reductase -3.08269
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -3.08168
ORC6 origin recognition complex, subunit 6 -3.0743
BACE2 beta-site APP-cleaving enzyme 2 -3.0723
TRMT5 tRNA methyltransferase 5 -3.06305
UBAC1 UBA domain containing 1 -3.0603
NCAPG non-SMC condensin I complex, subunit G -3.05622
TFAM transcription factor A, mitochondrial -3.0546
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -3.04975
MRM3 mitochondrial rRNA methyltransferase 3 -3.0399
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -3.0379
MED17 mediator complex subunit 17 -3.03705
EXOSC8 exosome component 8 -3.03415
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -3.03078
TRAIP TRAF interacting protein -3.02365
EBNA1BP2 EBNA1 binding protein 2 -3.0198
NLE1 notchless homolog 1 (Drosophila) -3.0161
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.0066
TEDC2 tubulin epsilon and delta complex 2 -3.0054
ZNF143 zinc finger protein 143 -2.99485
NUP43 nucleoporin 43kDa -2.99455
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -2.9806
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.98015
NUP37 nucleoporin 37kDa -2.979
NTAQ1 N-terminal glutamine amidase 1 -2.977
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.97695
TBPL1 TBP-like 1 -2.9756
GTSE1 G-2 and S-phase expressed 1 -2.97554
GARRE1 granule associated Rac and RHOG effector 1 -2.9736
POLM polymerase (DNA directed), mu -2.96195
BRIX1 BRX1, biogenesis of ribosomes -2.96105
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.9586
PMPCA peptidase (mitochondrial processing) alpha -2.95355
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -2.9501
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.92965
BZW2 basic leucine zipper and W2 domains 2 -2.91495
NEK4 NIMA-related kinase 4 -2.91395
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.91375
CDC25A cell division cycle 25A -2.91017
RBL1 retinoblastoma-like 1 -2.9065
DCXR dicarbonyl/L-xylulose reductase -2.8999
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.88725
RSBN1 round spermatid basic protein 1 -2.88695
SELL selectin L -2.8843
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 -2.87875
WASHC4 WASH complex subunit 4 -2.87732
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.87692
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -2.871
TFB2M transcription factor B2, mitochondrial -2.8657
FBXO17 F-box protein 17 -2.86365
APOO apolipoprotein O -2.8612
SUZ12 SUZ12 polycomb repressive complex 2 subunit -2.86083
FAM216A family with sequence similarity 216, member A -2.86005
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.85907
ZNF22 zinc finger protein 22 -2.85212
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.84952
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.8414
GCN1 GCN1 activator of EIF2AK4 -2.83682
AK8 adenylate kinase 8 -2.8317
MIS18A MIS18 kinetochore protein A -2.8288
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.82625
ACAA1 acetyl-CoA acyltransferase 1 -2.82303
NIPSNAP2 nipsnap homolog 2 -2.82115
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.8171
CENPI centromere protein I -2.81157
GGCT gamma-glutamylcyclotransferase -2.80445
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.80207
CENPX centromere protein X -2.8002
SNRPE small nuclear ribonucleoprotein polypeptide E -2.79945
HELLS helicase, lymphoid-specific -2.797
GEMIN2 gem (nuclear organelle) associated protein 2 -2.7959
AUNIP aurora kinase A and ninein interacting protein -2.7934
GPS1 G protein pathway suppressor 1 -2.78685
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.7827
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.7818
ILF2 interleukin enhancer binding factor 2 -2.7808
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.7805
SMC4 structural maintenance of chromosomes 4 -2.77997
DUT deoxyuridine triphosphatase -2.77772
URGCP upregulator of cell proliferation -2.7776
NDC1 NDC1 transmembrane nucleoporin -2.7725
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.76898
THUMPD2 THUMP domain containing 2 -2.7681
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.7623
NELFB negative elongation factor complex member B -2.75495
MAT2B methionine adenosyltransferase II, beta -2.74925
HMGN2 high mobility group nucleosomal binding domain 2 -2.7446
BOP1 block of proliferation 1 -2.7438
ZBTB32 zinc finger and BTB domain containing 32 -2.74285
ARHGAP11A Rho GTPase activating protein 11A -2.7393
TMEM131L transmembrane 131 like -2.7371
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.71985
CKAP2 cytoskeleton associated protein 2 -2.7121
DCP2 decapping mRNA 2 -2.70705
CCDC59 coiled-coil domain containing 59 -2.6921
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.6888
FASTKD3 FAST kinase domains 3 -2.68805
CRLF3 cytokine receptor-like factor 3 -2.68635
RAD51AP1 RAD51 associated protein 1 -2.68105
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.6755
TEFM transcription elongation factor, mitochondrial -2.67205
MORC3 MORC family CW-type zinc finger 3 -2.67185
INTS15 integrator complex subunit 15 -2.66895
RNF38 ring finger protein 38 -2.66875
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.657
FBXO21 F-box protein 21 -2.654
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.65365
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -2.65305
CENPF centromere protein F, 350/400kDa -2.64983
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.64015
NT5DC2 5'-nucleotidase domain containing 2 -2.6316
CLEC7A C-type lectin domain family 7, member A -2.6294
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.62815
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 -2.6267
RPL39L ribosomal protein L39-like -2.62115
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.61945
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.61675
ZNF83 zinc finger protein 83 -2.61385
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -2.6123
RXYLT1 ribitol xylosyltransferase 1 -2.6069
GAR1 GAR1 ribonucleoprotein -2.59465
MCM9 minichromosome maintenance complex component 9 -2.59315
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.592
GPHN gephyrin -2.5877
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -2.58555
CCNE2 cyclin E2 -2.58133
USP39 ubiquitin specific peptidase 39 -2.5703
USP1 ubiquitin specific peptidase 1 -2.5694
ZWINT ZW10 interacting kinetochore protein -2.5688
TMEM38B transmembrane protein 38B -2.5632
NOL11 nucleolar protein 11 -2.56305
ZNF107 zinc finger protein 107 -2.5616
TUBA3C tubulin, alpha 3c -2.5565
IGLL1 immunoglobulin lambda-like polypeptide 1 -2.5552
DPYD dihydropyrimidine dehydrogenase -2.5532
MTPAP mitochondrial poly(A) polymerase -2.54755
NUP42 nucleoporin 42 -2.5438
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.54255
RBM14-RBM4 RBM14-RBM4 readthrough -2.54105
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.54013
MAK16 MAK16 homolog (S. cerevisiae) -2.5368
CDCA4 cell division cycle associated 4 -2.5358
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 -2.5354
OBI1 ORC ubiquitin ligase 1 -2.5347
MGA MGA, MAX dimerization protein -2.53035
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.5274
CDKN3 cyclin-dependent kinase inhibitor 3 -2.52615
NPM3 nucleophosmin/nucleoplasmin 3 -2.5237
NOP16 NOP16 nucleolar protein -2.52225
GTF2A2 general transcription factor IIA, 2, 12kDa -2.5212
RANGAP1 Ran GTPase activating protein 1 -2.52067
CDC7 cell division cycle 7 -2.51515
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.51408
TIMELESS timeless circadian clock -2.51195
TCOF1 Treacher Collins-Franceschetti syndrome 1 -2.50997
TIPRL TOR signaling pathway regulator -2.50915
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.50845
RRM2 ribonucleotide reductase M2 -2.50392
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -2.49995
RAB33B RAB33B, member RAS oncogene family -2.49945
MRPL12 mitochondrial ribosomal protein L12 -2.4981
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.4935
POLK polymerase (DNA directed) kappa -2.49335
TMEM177 transmembrane protein 177 -2.4924
ISOC1 isochorismatase domain containing 1 -2.4924
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -2.49125
GALE UDP-galactose-4-epimerase -2.4897
TBRG4 transforming growth factor beta regulator 4 -2.47927
BATF3 basic leucine zipper transcription factor, ATF-like 3 -2.47515
ASDURF ASNSD1 upstream open reading frame -2.4743
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -2.47275
SPOUT1 SPOUT domain containing methyltransferase 1 -2.46885
RAD21 RAD21 homolog (S. pombe) -2.46595
ADISSP adipose secreted signaling protein -2.46578
TLCD3A TLC domain containing 3A -2.46445
TMEM109 transmembrane protein 109 -2.457
NASP nuclear autoantigenic sperm protein (histone-binding) -2.4563
COASY CoA synthase -2.45212
WDR76 WD repeat domain 76 -2.4509
ATAD5 ATPase family, AAA domain containing 5 -2.4446
TP53RK TP53 regulating kinase -2.44445
CAND1 cullin-associated and neddylation-dissociated 1 -2.43958
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.4327
ATG3 autophagy related 3 -2.432
FAM111A family with sequence similarity 111, member A -2.4285
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.4208
MRPL44 mitochondrial ribosomal protein L44 -2.41575
INCENP inner centromere protein antigens 135/155kDa -2.4144
AHCTF1 AT hook containing transcription factor 1 -2.4118
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -2.40642
CENPC centromere protein C -2.4054
NRF1 nuclear respiratory factor 1 -2.40375
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.3965
COQ3 coenzyme Q3 methyltransferase -2.3962
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -2.39615
PYCR3 pyrroline-5-carboxylate reductase 3 -2.3924
CORO1A coronin, actin binding protein, 1A -2.3882
TTF1 transcription termination factor, RNA polymerase I -2.38737
AARS1 alanyl-tRNA synthetase 1 -2.38595
AAAS achalasia, adrenocortical insufficiency, alacrimia -2.38465
NTHL1 nth endonuclease III-like 1 (E. coli) -2.3844
TWNK twinkle mtDNA helicase -2.3804
PSMC3IP PSMC3 interacting protein -2.38023
ASB9 ankyrin repeat and SOCS box containing 9 -2.37945
SEPHS1 selenophosphate synthetase 1 -2.37905
CUL1 cullin 1 -2.37885
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -2.37775
TEX30 testis expressed 30 -2.3763
PEPD peptidase D -2.3743
TSFM Ts translation elongation factor, mitochondrial -2.37235
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.3722
CEP76 centrosomal protein 76kDa -2.36525
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -2.3638
PUDP pseudouridine 5'-phosphatase -2.36125
MCRS1 microspherule protein 1 -2.36095
UBA1 ubiquitin-like modifier activating enzyme 1 -2.3595
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) -2.35895
KCTD12 potassium channel tetramerization domain containing 12 -2.3586
RNPS1 RNA binding protein S1, serine-rich domain -2.35763
ANAPC1 anaphase promoting complex subunit 1 -2.35675
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 -2.35625
OXCT1 3-oxoacid CoA transferase 1 -2.35555
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.3528
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.3494
EPCIP exosomal polycystin 1 interacting protein -2.3493
EXOSC9 exosome component 9 -2.34885
TUBA3E tubulin, alpha 3e -2.3457
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.34242
NOLC1 nucleolar and coiled-body phosphoprotein 1 -2.34052
COG2 component of oligomeric golgi complex 2 -2.33725
GEMIN4 gem (nuclear organelle) associated protein 4 -2.3339
GPN3 GPN-loop GTPase 3 -2.32995
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.3298
COQ4 coenzyme Q4 -2.31665
HAT1 histone acetyltransferase 1 -2.3125
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 -2.31241
WRAP53 WD repeat containing, antisense to TP53 -2.30942
PA2G4 proliferation-associated 2G4, 38kDa -2.30577
RIC8B RIC8 guanine nucleotide exchange factor B -2.30415
CNOT3 CCR4-NOT transcription complex, subunit 3 -2.30345
IGFLR1 IGF-like family receptor 1 -2.3028
PRR5 proline rich 5 (renal) -2.3025
MRPS34 mitochondrial ribosomal protein S34 -2.30017
GTPBP8 GTP-binding protein 8 (putative) -2.30005
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.29915
RCC1L RCC1 like -2.2978
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.2966
MRPL37 mitochondrial ribosomal protein L37 -2.2953
CACYBP calcyclin binding protein -2.29451
SNRPG small nuclear ribonucleoprotein polypeptide G -2.2933
ATF5 activating transcription factor 5 -2.29257
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.2902
NFYB nuclear transcription factor Y, beta -2.28982
LYSET lysosomal enzyme trafficking factor -2.2888
BARD1 BRCA1 associated RING domain 1 -2.28795
CPOX coproporphyrinogen oxidase -2.2833
RAD54B RAD54 homolog B (S. cerevisiae) -2.2758
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -2.27525
GCA grancalcin, EF-hand calcium binding protein -2.27425
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.2728
EIF4E eukaryotic translation initiation factor 4E -2.27245
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.27145
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.2692
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 -2.26828
NPIPB6 nuclear pore complex interacting protein family, member B6 -2.2616
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) -2.25905
RBBP8 retinoblastoma binding protein 8 -2.25855
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.25785
CCT2 chaperonin containing TCP1, subunit 2 (beta) -2.25763
PCP4 Purkinje cell protein 4 -2.2576
TRIM28 tripartite motif containing 28 -2.25105
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.24983
PUF60 poly-U binding splicing factor 60KDa -2.24805
RUVBL2 RuvB-like AAA ATPase 2 -2.2479
PRDX4 peroxiredoxin 4 -2.2451
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -2.24475
SKIC8 SKI8 subunit of superkiller complex -2.23658
PALS2 protein associated with LIN7 2, MAGUK p55 family member -2.23645
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -2.234
ACY1 aminoacylase 1 -2.2339
MRPL58 mitochondrial ribosomal protein L58 -2.23335
H2AX H2A.X variant histone -2.23275
ANKRD49 ankyrin repeat domain 49 -2.2326
NDC80 NDC80 kinetochore complex component -2.23105
HSPE1 heat shock 10kDa protein 1 -2.23075
PRPF31 pre-mRNA processing factor 31 -2.22987
ZNF200 zinc finger protein 200 -2.22837
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.22655
FAAP100 FA core complex associated protein 100 -2.2256
PCLAF PCNA clamp associated factor -2.22333
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.2227
PRRX1 paired related homeobox 1 -2.22145
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -2.22108
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -2.2193
EMC8 ER membrane protein complex subunit 8 -2.21645
AHCY adenosylhomocysteinase -2.21595
NUBP2 nucleotide binding protein 2 -2.21085
MTERF3 mitochondrial transcription termination factor 3 -2.2084
STIL SCL/TAL1 interrupting locus -2.2067
RAD51 RAD51 recombinase -2.20455
PARVB parvin, beta -2.20339
DCLRE1B DNA cross-link repair 1B -2.2012
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -2.2011
KHK ketohexokinase (fructokinase) -2.20062
MAGEB2 melanoma antigen family B2 -2.19545
FANCG Fanconi anemia, complementation group G -2.1954
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -2.18813
PAK1IP1 PAK1 interacting protein 1 -2.18755
THAP11 THAP domain containing 11 -2.18395
PRPF39 pre-mRNA processing factor 39 -2.1836
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.1819
WDR74 WD repeat domain 74 -2.18075
PRMT1 protein arginine methyltransferase 1 -2.1787
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.1785
TMEM267 transmembrane protein 267 -2.17835
PYDC1 PYD (pyrin domain) containing 1 -2.178
KIAA0586 KIAA0586 -2.17377
FTCD formimidoyltransferase cyclodeaminase -2.1704
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -2.16985
ZNF518A zinc finger protein 518A -2.1611
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -2.15735
BPHL biphenyl hydrolase-like (serine hydrolase) -2.15655
HMGB1 high mobility group box 1 -2.15408
LUM lumican -2.1538
AGMAT agmatine ureohydrolase (agmatinase) -2.1506
GRSF1 G-rich RNA sequence binding factor 1 -2.14912
SURF2 surfeit 2 -2.149
LRRC15 leucine rich repeat containing 15 -2.1485
SIVA1 SIVA1, apoptosis-inducing factor -2.1483
PAXBP1 PAX3 and PAX7 binding protein 1 -2.14663
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -2.1365
CRY1 cryptochrome circadian clock 1 -2.1355
MAGEC2 melanoma antigen family C2 -2.13495
EXOSC2 exosome component 2 -2.13185
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.13065
UBA3 ubiquitin-like modifier activating enzyme 3 -2.12805
WRAP73 WD repeat containing, antisense to TP73 -2.1278
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -2.1237
POLR1F RNA polymerase I subunit F -2.12225
DNAAF2 dynein, axonemal, assembly factor 2 -2.121
MRPL42 mitochondrial ribosomal protein L42 -2.1204
ZNF146 zinc finger protein 146 -2.1197
MDC1 mediator of DNA-damage checkpoint 1 -2.11687
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.11345
CENPU centromere protein U -2.1111
APOBEC3A_B APOBEC3A and APOBEC3B deletion hybrid -2.11077
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 -2.10945
TDG thymine-DNA glycosylase -2.1042
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.10343
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.1004
DNM1L dynamin 1-like -2.0972
CLEC4A C-type lectin domain family 4, member A -2.09472
CTSH cathepsin H -2.09375
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.09285
PPID peptidylprolyl isomerase D -2.08777
ECT2 epithelial cell transforming 2 -2.08735
BTBD2 BTB (POZ) domain containing 2 -2.0858
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.0844
PSIP1 PC4 and SFRS1 interacting protein 1 -2.0837
ZNF217 zinc finger protein 217 -2.07695
RIOX2 ribosomal oxygenase 2 -2.07398
MRPS15 mitochondrial ribosomal protein S15 -2.0739
CD58 CD58 molecule -2.07352
NOAZFP nucleolar atypical zinc finger -2.06855
AGK acylglycerol kinase -2.06842
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -2.06825
PTTG1 pituitary tumor-transforming 1 -2.06575
DKC1 dyskeratosis congenita 1, dyskerin -2.06498
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial -2.06355
CCR7 chemokine (C-C motif) receptor 7 -2.06315
CSK c-src tyrosine kinase -2.06295
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 -2.05718
WDR43 WD repeat domain 43 -2.0562
XPO1 exportin 1 -2.05285
INTS12 integrator complex subunit 12 -2.05245
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -2.0495
TRA2B transformer 2 beta homolog (Drosophila) -2.04847
NSD2 nuclear receptor binding SET domain protein 2 -2.04845
HDAC2 histone deacetylase 2 -2.04775
LIME1 Lck interacting transmembrane adaptor 1 -2.04645
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.045
AVL9 AVL9 homolog (S. cerevisiase) -2.04438
ANKRD10 ankyrin repeat domain 10 -2.0427
PAQR6 progestin and adipoQ receptor family member VI -2.04215
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.0416
SLC25A40 solute carrier family 25, member 40 -2.0413
MSH2 mutS homolog 2 -2.0409
PFAS phosphoribosylformylglycinamidine synthase -2.0401
MYG1 MYG1 exonuclease -2.03225
NUP160 nucleoporin 160kDa -2.02897
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -2.0281
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -2.0259
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.0246
RAB23 RAB23, member RAS oncogene family -2.02245
NXT1 nuclear transport factor 2-like export factor 1 -2.0224
LAS1L LAS1-like (S. cerevisiae) -2.02215
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.02175
SLC2A4RG SLC2A4 regulator -2.02165
EGR1 early growth response 1 -2.01853
GMNN geminin, DNA replication inhibitor -2.01612
DCPS decapping enzyme, scavenger -2.01605
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.01595
WDR82 WD repeat domain 82 -2.0157
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -2.01515
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -2.0132
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.0126
CS citrate synthase -2.01135
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.01111
FUS FUS RNA binding protein -2.01058
KIFBP kinesin family binding protein -2.0094
GEMIN6 gem (nuclear organelle) associated protein 6 -2.0072
COTL1 coactosin-like F-actin binding protein 1 -2.00425
PRMT3 protein arginine methyltransferase 3 -2.00285