CRCGN017_MCF10A.WT.HP_24H:E18 Gene Set
Genes
44 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HBA1
|
hemoglobin, alpha 1
|
7.85905
|
|
HBB
|
hemoglobin, beta
|
7.27085
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
5.1331
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.82665
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
4.7386
|
|
NUCB2
|
nucleobindin 2
|
4.3476
|
|
VGLL4
|
vestigial-like family member 4
|
3.44795
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.92125
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.59995
|
|
COQ8A
|
coenzyme Q8A
|
2.49455
|
|
PXMP2
|
peroxisomal membrane protein 2, 22kDa
|
2.21672
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.09775
|
|
SRP9
|
signal recognition particle 9kDa
|
2.0751
|
|
ARPC4-TTLL3
|
ARPC4-TTLL3 readthrough
|
2.06933
|
|
GTF3A
|
general transcription factor IIIA
|
2.05315
|
|
ERN2
|
endoplasmic reticulum to nucleus signaling 2
|
2.02445
|
|
MRFAP1L1
|
Morf4 family associated protein 1-like 1
|
2.0136
|
|
CSNK1A1
|
casein kinase 1, alpha 1
|
2.00617
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ACOT9
|
acyl-CoA thioesterase 9
|
-5.43355
|
|
DNM1L
|
dynamin 1-like
|
-5.3186
|
|
GDF15
|
growth differentiation factor 15
|
-5.26775
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.8736
|
|
KRT14
|
keratin 14, type I
|
-4.8624
|
|
COG2
|
component of oligomeric golgi complex 2
|
-4.8217
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
-3.4084
|
|
YARS2
|
tyrosyl-tRNA synthetase 2, mitochondrial
|
-3.2986
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-3.17358
|
|
CAPRIN2
|
caprin family member 2
|
-2.7599
|
|
NANOS3
|
nanos homolog 3 (Drosophila)
|
-2.6616
|
|
MT2A
|
metallothionein 2A
|
-2.64325
|
|
MYO5A
|
myosin VA (heavy chain 12, myoxin)
|
-2.5154
|
|
CHORDC1
|
cysteine and histidine-rich domain (CHORD) containing 1
|
-2.51333
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
-2.43568
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.4253
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-2.4093
|
|
BNIP2
|
BCL2/adenovirus E1B 19kDa interacting protein 2
|
-2.3416
|
|
VPS33B
|
vacuolar protein sorting 33 homolog B (yeast)
|
-2.33535
|
|
CACNA2D3
|
calcium channel, voltage-dependent, alpha 2/delta subunit 3
|
-2.3117
|
|
WASHC4
|
WASH complex subunit 4
|
-2.22412
|
|
MYH3
|
myosin, heavy chain 3, skeletal muscle, embryonic
|
-2.188
|
|
SPRED2
|
sprouty-related, EVH1 domain containing 2
|
-2.12542
|
|
BRINP3
|
bone morphogenetic protein/retinoic acid inducible neural-specific 3
|
-2.11715
|
|
KATNBL1
|
katanin p80 subunit B-like 1
|
-2.0979
|
|
MICAL2
|
microtubule associated monooxygenase, calponin and LIM domain containing 2
|
-2.02828
|
