CRCGN017_MCF10A.WT.HP_24H:E20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triphenylphosphine oxide 32.23 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:E20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.92655
SNAP25 synaptosomal-associated protein, 25kDa 4.55935
WIF1 WNT inhibitory factor 1 4.5516
ACAA1 acetyl-CoA acyltransferase 1 3.30785
HBB hemoglobin, beta 2.9767
USP6NL USP6 N-terminal like 2.94145
PLS1 plastin 1 2.49155
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.24105
KAT6B K(lysine) acetyltransferase 6B 2.03889

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -4.9415
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.83925
TES testin LIM domain protein -4.5481
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -4.15385
CAB39 calcium binding protein 39 -3.22585
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.76662
WASHC4 WASH complex subunit 4 -2.36105