CRCGN017_MCF10A.WT.HP_24H:E21 Gene Set
Genes
36 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:E21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
5.4175
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.2909
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
5.16022
|
|
STK10
|
serine/threonine kinase 10
|
4.97402
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
4.8588
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.30277
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
2.859
|
|
NRBF2
|
nuclear receptor binding factor 2
|
2.67135
|
|
RNF4
|
ring finger protein 4
|
2.37285
|
|
POLD4
|
polymerase (DNA-directed), delta 4, accessory subunit
|
2.2841
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.11225
|
|
HLA-DRB1
|
major histocompatibility complex, class II, DR beta 1
|
2.04204
|
|
FBXO7
|
F-box protein 7
|
2.0374
|
|
HOXA1
|
homeobox A1
|
2.0286
|
|
MIS12
|
MIS12 kinetochore complex component
|
2.0101
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TEX10
|
testis expressed 10
|
-5.44605
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-5.17295
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.65745
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.45375
|
|
S100A8
|
S100 calcium binding protein A8
|
-3.4119
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
-3.18668
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-2.9674
|
|
WASHC4
|
WASH complex subunit 4
|
-2.95443
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
-2.92422
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
-2.8475
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.8079
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.65925
|
|
REV3L
|
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
|
-2.5515
|
|
MAPKAPK3
|
mitogen-activated protein kinase-activated protein kinase 3
|
-2.4253
|
|
FPGS
|
folylpolyglutamate synthase
|
-2.21695
|
|
ATF5
|
activating transcription factor 5
|
-2.17443
|
|
EMX2
|
empty spiracles homeobox 2
|
-2.16685
|
|
HIVEP2
|
human immunodeficiency virus type I enhancer binding protein 2
|
-2.16655
|
|
TMEM120B
|
transmembrane protein 120B
|
-2.08495
|
|
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1
|
-2.0118
|
|
REV1
|
REV1, polymerase (DNA directed)
|
-2.00145
|
