CRCGN017_MCF10A.WT.HP_24H:F02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta-carotene 17.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:F02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.70937
CCL2 chemokine (C-C motif) ligand 2 4.42126
ZNF318 zinc finger protein 318 4.0007
TIAM1 T-cell lymphoma invasion and metastasis 1 3.79031
NNT nicotinamide nucleotide transhydrogenase 3.74634
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 3.41213
MCUR1 mitochondrial calcium uniporter regulator 1 2.24304
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.16869

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -7.81777
KIF14 kinesin family member 14 -4.61854
ZDHHC6 zinc finger, DHHC-type containing 6 -3.66423
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -3.60216
NR2F6 nuclear receptor subfamily 2, group F, member 6 -3.03275
CYCS cytochrome c, somatic -2.80091
CD81 CD81 molecule -2.61814
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.57855
SGK1 serum/glucocorticoid regulated kinase 1 -2.55092
CHIC2 cysteine-rich hydrophobic domain 2 -2.50389
KRT14 keratin 14, type I -2.3288
UBE3C ubiquitin protein ligase E3C -2.05588
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.01185