CRCGN017_MCF10A.WT.HP_24H:F04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description c.i. acid red 114 101.47 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

67 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UGDH UDP-glucose 6-dehydrogenase 3.77938
HMGA2 high mobility group AT-hook 2 3.57866
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.17394
AXIN1 axin 1 3.07674
FHL2 four and a half LIM domains 2 3.03623
ARID5B AT rich interactive domain 5B (MRF1-like) 2.93353
RBKS ribokinase 2.79957
NLRP4 NLR family, pyrin domain containing 4 2.66051
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.63474
COL4A1 collagen, type IV, alpha 1 2.47065
PLA2G15 phospholipase A2, group XV 2.45997
SSBP2 single-stranded DNA binding protein 2 2.45383
GATD3 glutamine amidotransferase class 1 domain containing 3 2.40566
NIPSNAP1 nipsnap homolog 1 (C. elegans) 2.36405
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 2.33257
ADA adenosine deaminase 2.32945
ZNF692 zinc finger protein 692 2.30289
INSIG1 insulin induced gene 1 2.28255
ECH1 enoyl CoA hydratase 1, peroxisomal 2.24711
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.24074
TSPOAP1 TSPO associated protein 1 2.1517
LRP5 low density lipoprotein receptor-related protein 5 2.13985
STK32B serine/threonine kinase 32B 2.13313
RNF144A ring finger protein 144A 2.03657
CTBP1 C-terminal binding protein 1 2.03492
TRIP10 thyroid hormone receptor interactor 10 2.03389
ENO3 enolase 3 (beta, muscle) 2.01372
CPT1B carnitine palmitoyltransferase 1B (muscle) 2.00173

decreased expression

Symbol Name Standardized Value
OXA1L oxidase (cytochrome c) assembly 1-like -5.5738
GOLT1B golgi transport 1B -5.11442
SGK1 serum/glucocorticoid regulated kinase 1 -4.39397
EBNA1BP2 EBNA1 binding protein 2 -4.14511
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.86422
HOXA5 homeobox A5 -3.85081
ENOPH1 enolase-phosphatase 1 -3.80087
RGS2 regulator of G-protein signaling 2 -3.70027
MAPK13 mitogen-activated protein kinase 13 -3.58372
PRR15L proline rich 15-like -3.43435
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -3.38238
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.27302
TXNRD1 thioredoxin reductase 1 -3.23486
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -3.22225
CCDC86 coiled-coil domain containing 86 -3.19207
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.15013
LAP3 leucine aminopeptidase 3 -3.10706
CBR3 carbonyl reductase 3 -2.74805
BAD BCL2-associated agonist of cell death -2.71612
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -2.67276
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.53414
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.53395
KRT14 keratin 14, type I -2.49086
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.39868
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.38656
CDC20 cell division cycle 20 -2.35759
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.34912
ATRIP ATR interacting protein -2.3355
GAR1 GAR1 ribonucleoprotein -2.30021
TMCO1 transmembrane and coiled-coil domains 1 -2.28758
LMO2 LIM domain only 2 (rhombotin-like 1) -2.17685
ELOVL2 ELOVL fatty acid elongase 2 -2.15605
PRMT5 protein arginine methyltransferase 5 -2.13865
PSRC1 proline/serine-rich coiled-coil 1 -2.12812
GCLM glutamate-cysteine ligase, modifier subunit -2.12298
RPS5 ribosomal protein S5 -2.09193
TXNDC9 thioredoxin domain containing 9 -2.0815
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.02193
UEVLD UEV and lactate/malate dehyrogenase domains -2.00815