CRCGN017_MCF10A.WT.HP_24H:F06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description c.i. acid red 114 11.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:F06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EAPP E2F-associated phosphoprotein 5.15988
KLHL21 kelch-like family member 21 3.6486
TBX2 T-box 2 3.6345
MAMLD1 mastermind-like domain containing 1 3.60991
SPAG4 sperm associated antigen 4 3.08898
MAN2B1 mannosidase, alpha, class 2B, member 1 2.81954
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.67238
SRP54 signal recognition particle 54kDa 2.38189
ADGRE5 adhesion G protein-coupled receptor E5 2.35038
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.23127
OLFML2B olfactomedin-like 2B 2.18294
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.13344

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.91794
TXNDC9 thioredoxin domain containing 9 -4.84862
TES testin LIM domain protein -4.83503
VDAC1 voltage-dependent anion channel 1 -3.79131
S100A8 S100 calcium binding protein A8 -3.63485
LDHD lactate dehydrogenase D -3.41039
TUBA4A tubulin, alpha 4a -3.37245
HMG20B high mobility group 20B -3.24091
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.75821
RXYLT1 ribitol xylosyltransferase 1 -2.52822
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.46549
COPS7A COP9 signalosome subunit 7A -2.40738
SGK1 serum/glucocorticoid regulated kinase 1 -2.35545
TDP2 tyrosyl-DNA phosphodiesterase 2 -2.17423
TMEM127 transmembrane protein 127 -2.15243
LAP3 leucine aminopeptidase 3 -2.13649
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.05678
HEATR1 HEAT repeat containing 1 -2.03579