CRCGN017_MCF10A.WT.HP_24H:F09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description scopolamine hydrobromide tri-hydrate 11.22 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:F09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD6 abhydrolase domain containing 6 3.90623
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.63855
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.16058
UNG uracil-DNA glycosylase 2.07465
SMN2 survival of motor neuron 2, centromeric 2.0669
BCAP31 B-cell receptor-associated protein 31 2.0649
HNRNPM heterogeneous nuclear ribonucleoprotein M 2.05015

decreased expression

Symbol Name Standardized Value
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -5.3664
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.3636
CD58 CD58 molecule -3.42522
BASP1 brain abundant, membrane attached signal protein 1 -3.2631
MSMO1 methylsterol monooxygenase 1 -3.24705
SOAT2 sterol O-acyltransferase 2 -2.75375
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -2.42425
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -2.22925
LIN37 lin-37 DREAM MuvB core complex component -2.2167
GPATCH1 G patch domain containing 1 -2.19725
TMEM147 transmembrane protein 147 -2.1946
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.189
DAPL1 death associated protein-like 1 -2.17945
DTX4 deltex 4, E3 ubiquitin ligase -2.1556
TRIM56 tripartite motif containing 56 -2.14705
NID2 nidogen 2 (osteonidogen) -2.08
MYL5 myosin, light chain 5, regulatory -2.0124