CRCGN017_MCF10A.WT.HP_24H:F19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o,o-diethyl o-(4-nitrophenyl) thiophosphate 101.97 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

29 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:F19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.77675
ADGRE5 adhesion G protein-coupled receptor E5 5.5448
IDE insulin-degrading enzyme 4.72095
AGR2 anterior gradient 2 4.4043
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.08945
KDM5D lysine (K)-specific demethylase 5D 3.30925
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.84645
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.55223
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.08695
MTX1 metaxin 1 2.02545

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -5.0038
HSPA8 heat shock 70kDa protein 8 -4.51237
PCCB propionyl CoA carboxylase, beta polypeptide -4.4969
NT5DC2 5'-nucleotidase domain containing 2 -3.71095
SGK1 serum/glucocorticoid regulated kinase 1 -3.2564
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.84035
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.73885
SMC1A structural maintenance of chromosomes 1A -2.68158
KDM5C lysine (K)-specific demethylase 5C -2.5071
KDM6A lysine (K)-specific demethylase 6A -2.48745
WASHC4 WASH complex subunit 4 -2.38805
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -2.37905
LMBR1L limb development membrane protein 1-like -2.15045
ZNF276 zinc finger protein 276 -2.0719
NKX2-2 NK2 homeobox 2 -2.07005
PUDP pseudouridine 5'-phosphatase -2.05815
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -2.05715
UPK3B uroplakin 3B -2.0278
PTPRR protein tyrosine phosphatase, receptor type, R -2.00348