CRCGN017_MCF10A.WT.HP_24H:F20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o,o-diethyl o-(4-nitrophenyl) thiophosphate 33.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:F20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 4.7557
LYN LYN proto-oncogene, Src family tyrosine kinase 3.22098
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.9933
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.87415
THAP12 THAP domain containing 12 2.34155
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.30235
RSF1 remodeling and spacing factor 1 2.20405
AAMDC adipogenesis associated, Mth938 domain containing 2.12545
PKN1 protein kinase N1 2.0214

decreased expression

Symbol Name Standardized Value
HEATR1 HEAT repeat containing 1 -3.5526
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.47385
SGK1 serum/glucocorticoid regulated kinase 1 -3.40515
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.8588
C1QBP complement component 1, q subcomponent binding protein -2.1565
SNX7 sorting nexin 7 -2.057