CRCGN017_MCF10A.WT.HP_24H:F21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o,o-diethyl o-(4-nitrophenyl) thiophosphate 11.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

62 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:F21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 4.7445
BCL7B B-cell CLL/lymphoma 7B 3.6751
TSEN2 TSEN2 tRNA splicing endonuclease subunit 3.5271
TIAM1 T-cell lymphoma invasion and metastasis 1 3.14278
ACAA1 acetyl-CoA acyltransferase 1 2.97677
HDGFL3 HDGF like 3 2.78645
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 2.4839
ZNF460 zinc finger protein 460 2.42495
MTUS2 microtubule associated tumor suppressor candidate 2 2.39985
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 2.3802
RPP38 ribonuclease P/MRP 38kDa subunit 2.37915
CERK ceramide kinase 2.31725
PECR peroxisomal trans-2-enoyl-CoA reductase 2.31185
SNRPN small nuclear ribonucleoprotein polypeptide N 2.24805
RCAN3 RCAN family member 3 2.2105
GPR88 G protein-coupled receptor 88 2.1971
CCDC70 coiled-coil domain containing 70 2.19545
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 2.18095
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 2.17255
MYH13 myosin, heavy chain 13, skeletal muscle 2.17195
TUBA8 tubulin, alpha 8 2.12485
USP2 ubiquitin specific peptidase 2 2.1194
SKI SKI proto-oncogene 2.11435
ATXN7L1 ataxin 7-like 1 2.10215
GPR6 G protein-coupled receptor 6 2.08595
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.07365
TUBGCP5 tubulin, gamma complex associated protein 5 2.0721
SPATA31C1 SPATA31 subfamily C, member 1 2.0646
CPLX2 complexin 2 2.06215
FBXO22 F-box protein 22 2.05125
HMHB1 histocompatibility (minor) HB-1 2.05045
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 2.03595
PNMA2 paraneoplastic Ma antigen 2 2.03218
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 2.02755
POU3F4 POU class 3 homeobox 4 2.0236
TMPRSS15 transmembrane protease, serine 15 2.0215
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.0146
FBXO24 F-box protein 24 2.00915
PLAGL2 pleiomorphic adenoma gene-like 2 2.0088

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -9.51433
ACOT9 acyl-CoA thioesterase 9 -4.9822
ISOC1 isochorismatase domain containing 1 -4.92285
CCNB1 cyclin B1 -4.83055
CCNB2 cyclin B2 -4.66275
HAT1 histone acetyltransferase 1 -4.6127
CD44 CD44 molecule (Indian blood group) -3.93988
CTNND1 catenin (cadherin-associated protein), delta 1 -3.76035
MSN moesin -3.36775
TLCD3A TLC domain containing 3A -3.34435
CCL22 chemokine (C-C motif) ligand 22 -3.11675
MICALL2 MICAL-like 2 -2.4018
MFSD12 major facilitator superfamily domain containing 12 -2.35267
LOC127933115 uncharacterized LOC127933115 -2.2637
APOO apolipoprotein O -2.218
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -2.1987
MT2A metallothionein 2A -2.1965
RAI1 retinoic acid induced 1 -2.1954
HSPA1A heat shock 70kDa protein 1A -2.19325
ALAS1 5'-aminolevulinate synthase 1 -2.178
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.12182
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 -2.0599
NME3 NME/NM23 nucleoside diphosphate kinase 3 -2.01555