CRCGN017_MCF10A.WT.HP_24H:G02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tris(1-chloro-2-propanyl) phosphate 33.66 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:G02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 3.42074
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.29848
ACAA1 acetyl-CoA acyltransferase 1 3.23589
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.80143
GPER1 G protein-coupled estrogen receptor 1 2.70045
ABHD4 abhydrolase domain containing 4 2.59386
COL11A1 collagen, type XI, alpha 1 2.49246
CERK ceramide kinase 2.40012
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.35781
COMP cartilage oligomeric matrix protein 2.2221
CCNA1 cyclin A1 2.14379
MAMLD1 mastermind-like domain containing 1 2.04364
CNPY3 canopy FGF signaling regulator 3 2.0346

decreased expression

Symbol Name Standardized Value
MRPS2 mitochondrial ribosomal protein S2 -3.71646
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.88536
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.8579
S100A8 S100 calcium binding protein A8 -2.73591
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.55837
MPC2 mitochondrial pyruvate carrier 2 -2.54069
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.38629
TRIB3 tribbles pseudokinase 3 -2.04237
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.00784