CRCGN017_MCF10A.WT.HP_24H:G07 Gene Set
Genes
46 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:G07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
5.4451
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
5.2273
|
|
TLR4
|
toll-like receptor 4
|
5.0
|
|
GATA2
|
GATA binding protein 2
|
4.60695
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.30665
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
3.78045
|
|
FZD7
|
frizzled class receptor 7
|
2.79
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.58497
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
2.3463
|
|
ADAMTS3
|
ADAM metallopeptidase with thrombospondin type 1 motif, 3
|
2.2073
|
|
PLS1
|
plastin 1
|
2.1759
|
|
TWNK
|
twinkle mtDNA helicase
|
2.1205
|
|
MTG1
|
mitochondrial ribosome-associated GTPase 1
|
2.07505
|
|
POPDC3
|
popeye domain containing 3
|
2.0022
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-5.65125
|
|
LAP3
|
leucine aminopeptidase 3
|
-5.1271
|
|
MT2A
|
metallothionein 2A
|
-5.0662
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-5.0
|
|
MT1X
|
metallothionein 1X
|
-4.55335
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-4.38708
|
|
CD81
|
CD81 molecule
|
-4.07925
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
-3.9521
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-3.7817
|
|
HOXA5
|
homeobox A5
|
-3.50915
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.76558
|
|
LINC02762
|
long intergenic non-protein coding RNA 2762
|
-2.62015
|
|
FPGS
|
folylpolyglutamate synthase
|
-2.6003
|
|
CDS2
|
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
|
-2.5916
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
-2.52053
|
|
TASP1
|
taspase, threonine aspartase, 1
|
-2.4384
|
|
PANK2
|
pantothenate kinase 2
|
-2.2904
|
|
CTSH
|
cathepsin H
|
-2.29025
|
|
WASHC4
|
WASH complex subunit 4
|
-2.28603
|
|
SERPING1
|
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
|
-2.2521
|
|
OAS2
|
2'-5'-oligoadenylate synthetase 2, 69/71kDa
|
-2.2489
|
|
MSN
|
moesin
|
-2.2004
|
|
SPRED2
|
sprouty-related, EVH1 domain containing 2
|
-2.19115
|
|
SPRING1
|
SREBF pathway regulator in golgi 1
|
-2.1708
|
|
MZT2A
|
mitotic spindle organizing protein 2A
|
-2.15475
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.14792
|
|
NXT2
|
nuclear transport factor 2-like export factor 2
|
-2.11573
|
|
SNRPB2
|
small nuclear ribonucleoprotein polypeptide B
|
-2.0749
|
|
IRS1
|
insulin receptor substrate 1
|
-2.0599
|
|
SEC23B
|
Sec23 homolog B (S. cerevisiae)
|
-2.0563
|
|
HOXA4
|
homeobox A4
|
-2.04605
|
|
CDC73
|
cell division cycle 73
|
-2.01805
|
