CRCGN017_MCF10A.WT.HP_24H:H01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosopiperidine 100.46 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:H01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.20227
CCNA1 cyclin A1 4.11272
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.09959
TEX10 testis expressed 10 3.66744
ZNF586 zinc finger protein 586 3.31397
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.2393
GRB10 growth factor receptor-bound protein 10 2.38809
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.32417

decreased expression

Symbol Name Standardized Value
CCDC86 coiled-coil domain containing 86 -4.74142
CD58 CD58 molecule -4.51658
GOLT1B golgi transport 1B -4.37842
GDF15 growth differentiation factor 15 -4.23789
CAB39 calcium binding protein 39 -4.18322
GLRX glutaredoxin (thioltransferase) -4.01607
KRT14 keratin 14, type I -3.4465
TUBA4A tubulin, alpha 4a -2.88718
ACAA1 acetyl-CoA acyltransferase 1 -2.637