CRCGN017_MCF10A.WT.HP_24H:H03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosopiperidine 11.16 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:H03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.70403
CHMP6 charged multivesicular body protein 6 4.36403
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.35433
ACAA1 acetyl-CoA acyltransferase 1 2.67896
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.66247
HBA1 hemoglobin, alpha 1 2.38925
PDLIM1 PDZ and LIM domain 1 2.09475
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.09193
HBB hemoglobin, beta 2.04908

decreased expression

Symbol Name Standardized Value
CCDC86 coiled-coil domain containing 86 -2.81101
HEATR1 HEAT repeat containing 1 -2.62317
PFN1 profilin 1 -2.60785
TLCD3A TLC domain containing 3A -2.44731
WASHC4 WASH complex subunit 4 -2.23659
S100A8 S100 calcium binding protein A8 -2.10526