CRCGN017_MCF10A.WT.HP_24H:H05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hexylresorcinol 33.82 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:H05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TLR4 toll-like receptor 4 4.44276
IFNAR1 interferon (alpha, beta and omega) receptor 1 4.07787
ICAM3 intercellular adhesion molecule 3 3.95421
CXCR4 chemokine (C-X-C motif) receptor 4 3.52515
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 3.3701
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.07154
KLHL21 kelch-like family member 21 3.06548
NUCB2 nucleobindin 2 2.69433
SNAP25 synaptosomal-associated protein, 25kDa 2.61743
CXCL2 chemokine (C-X-C motif) ligand 2 2.6168
CERK ceramide kinase 2.55381
ACAA1 acetyl-CoA acyltransferase 1 2.40292
WIF1 WNT inhibitory factor 1 2.23972
STX1A syntaxin 1A (brain) 2.21492
HMGA2 high mobility group AT-hook 2 2.18375
CHI3L2 chitinase 3-like 2 2.17434
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.13811
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 2.11218
MID1IP1 MID1 interacting protein 1 2.0863

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -4.99434
CCNB2 cyclin B2 -4.05367
NPDC1 neural proliferation, differentiation and control, 1 -3.86513
DERA deoxyribose-phosphate aldolase (putative) -3.78141
HMG20B high mobility group 20B -3.36429
SLC35F2 solute carrier family 35, member F2 -3.27687
PCNA proliferating cell nuclear antigen -3.22252
TRAPPC3 trafficking protein particle complex 3 -2.91824
VDAC1 voltage-dependent anion channel 1 -2.75938
MRPS15 mitochondrial ribosomal protein S15 -2.36921
PRR15L proline rich 15-like -2.35273
REEP5 receptor accessory protein 5 -2.3132
BAD BCL2-associated agonist of cell death -2.12649
CHIC2 cysteine-rich hydrophobic domain 2 -2.11514
ATF5 activating transcription factor 5 -2.03537