CRCGN017_MCF10A.WT.HP_24H:H06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hexylresorcinol 11.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:H06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 5.82947
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.6421
HBB hemoglobin, beta 4.00046
PLSCR1 phospholipid scramblase 1 3.7628
HBA1 hemoglobin, alpha 1 3.72347
SNX11 sorting nexin 11 3.35723
MAMLD1 mastermind-like domain containing 1 3.22015
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.03071
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.89304
ZNF451 zinc finger protein 451 2.26239
RAB3A RAB3A, member RAS oncogene family 2.24529
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 2.00638

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -7.09695
LAP3 leucine aminopeptidase 3 -4.92437
MRPS16 mitochondrial ribosomal protein S16 -4.83418
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.32311
CANT1 calcium activated nucleotidase 1 -3.29911
BASP1 brain abundant, membrane attached signal protein 1 -2.89074
KRT14 keratin 14, type I -2.8811
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.5784
CD58 CD58 molecule -2.52683
TRAPPC3 trafficking protein particle complex 3 -2.52629
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.43124
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 -2.35571
DNM1L dynamin 1-like -2.3242
SEC24C SEC24 family member C -2.14953
REEP5 receptor accessory protein 5 -2.13841
DNA2 DNA replication helicase/nuclease 2 -2.09378
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.01834