CRCGN017_MCF10A.WT.HP_24H:H10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tetracycline 101.47 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

1013 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 9.4748
GFPT1 glutamine--fructose-6-phosphate transaminase 1 9.3179
WIF1 WNT inhibitory factor 1 8.7532
GLRX glutaredoxin (thioltransferase) 8.31815
NUCB2 nucleobindin 2 8.2673
AARS1 alanyl-tRNA synthetase 1 7.9677
PYCR1 pyrroline-5-carboxylate reductase 1 7.126
CHMP4B charged multivesicular body protein 4B 6.94255
AGR2 anterior gradient 2 6.5296
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 6.4242
CNRIP1 cannabinoid receptor interacting protein 1 6.4201
TXNRD1 thioredoxin reductase 1 6.39925
SLC35B1 solute carrier family 35, member B1 6.2337
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 5.96852
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 5.9219
CCNA1 cyclin A1 5.8911
LOC128125814 uncharacterized LOC128125814 5.7905
CTSL cathepsin L 5.74015
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 5.71408
PSAT1 phosphoserine aminotransferase 1 5.6461
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 5.54265
CXCL2 chemokine (C-X-C motif) ligand 2 5.5294
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.48325
NANOS3 nanos homolog 3 (Drosophila) 5.4617
FYN FYN proto-oncogene, Src family tyrosine kinase 5.41448
CHIC2 cysteine-rich hydrophobic domain 2 5.32165
HMOX1 heme oxygenase 1 5.30815
UFM1 ubiquitin-fold modifier 1 5.2955
GARS1 glycyl-tRNA synthetase 1 5.25465
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 5.1764
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 5.13275
PHGDH phosphoglycerate dehydrogenase 5.11055
HLA-DMA major histocompatibility complex, class II, DM alpha 5.08805
VSIG2 V-set and immunoglobulin domain containing 2 5.08722
MOK MOK protein kinase 5.03965
ATF4 activating transcription factor 4 5.0153
WFS1 Wolfram syndrome 1 (wolframin) 4.93055
TBPL1 TBP-like 1 4.8503
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 4.8463
LOXL1 lysyl oxidase-like 1 4.81215
CARS1 cysteinyl-tRNA synthetase 1 4.78018
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 4.74045
YARS1 tyrosyl-tRNA synthetase 1 4.7384
FOS FBJ murine osteosarcoma viral oncogene homolog 4.7252
TRIB3 tribbles pseudokinase 3 4.63635
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 4.636
MANF mesencephalic astrocyte-derived neurotrophic factor 4.61815
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 4.57998
GRB10 growth factor receptor-bound protein 10 4.56372
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 4.5273
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 4.47498
KLHL21 kelch-like family member 21 4.44465
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.40505
CCS copper chaperone for superoxide dismutase 4.4006
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 4.38385
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 4.31505
RPN1 ribophorin I 4.31345
MSRA methionine sulfoxide reductase A 4.27695
PTPRG protein tyrosine phosphatase, receptor type, G 4.2555
SARS1 seryl-tRNA synthetase 1 4.1919
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 4.1913
CCP110 centriolar coiled coil protein 110kDa 4.1569
FHL2 four and a half LIM domains 2 4.1559
HYOU1 hypoxia up-regulated 1 4.1164
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 4.0921
XPOT exportin, tRNA 4.08975
KCTD5 potassium channel tetramerization domain containing 5 4.0838
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 4.08113
GMPPA GDP-mannose pyrophosphorylase A 4.0784
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 4.07145
EPRS1 glutamyl-prolyl-tRNA synthetase 1 4.06597
TES testin LIM domain protein 3.99552
ECH1 enoyl CoA hydratase 1, peroxisomal 3.9269
ARCN1 archain 1 3.9165
CNPY3 canopy FGF signaling regulator 3 3.90745
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.8967
MARS1 methionyl-tRNA synthetase 1 3.8959
SCFD1 sec1 family domain containing 1 3.88825
NLRP4 NLR family, pyrin domain containing 4 3.87575
LARP6 La ribonucleoprotein domain family, member 6 3.82665
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 3.82335
TARS1 threonyl-tRNA synthetase 1 3.79275
GOLT1A golgi transport 1A 3.78565
COPB1 coatomer protein complex, subunit beta 1 3.78285
FKBP14 FK506 binding protein 14, 22 kDa 3.77345
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 3.7621
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 3.7343
IFT88 intraflagellar transport 88 3.72025
CCDC92 coiled-coil domain containing 92 3.6534
STX1A syntaxin 1A (brain) 3.6246
ARF4 ADP-ribosylation factor 4 3.61542
HBB hemoglobin, beta 3.61175
ATF6 activating transcription factor 6 3.6089
FNDC4 fibronectin type III domain containing 4 3.59315
UGDH UDP-glucose 6-dehydrogenase 3.5304
AZIN2 antizyme inhibitor 2 3.51705
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 3.50635
ASNS asparagine synthetase (glutamine-hydrolyzing) 3.4835
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 3.4687
NPC1 Niemann-Pick disease, type C1 3.4619
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.4332
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 3.42665
SERP1 stress-associated endoplasmic reticulum protein 1 3.42643
DHRS4 dehydrogenase/reductase (SDR family) member 4 3.38535
PPCS phosphopantothenoylcysteine synthetase 3.3757
STAMBP STAM binding protein 3.375
STC2 stanniocalcin 2 3.36385
SSR1 signal sequence receptor, alpha 3.35901
CANT1 calcium activated nucleotidase 1 3.3454
TM9SF2 transmembrane 9 superfamily member 2 3.30815
ZPR1 ZPR1 zinc finger 3.30795
CALU calumenin 3.29949
GORASP2 golgi reassembly stacking protein 2, 55kDa 3.28088
RAP1GAP RAP1 GTPase activating protein 3.2759
GOLT1B golgi transport 1B 3.2589
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 3.2446
SIL1 SIL1 nucleotide exchange factor 3.2257
SCCPDH saccharopine dehydrogenase (putative) 3.21508
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 3.21385
ABHD4 abhydrolase domain containing 4 3.2137
SLC31A1 solute carrier family 31 (copper transporter), member 1 3.21255
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 3.20065
WIPI1 WD repeat domain, phosphoinositide interacting 1 3.19665
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 3.18983
NARS1 asparaginyl-tRNA synthetase 1 3.1726
ITCH itchy E3 ubiquitin protein ligase 3.14893
OPLAH 5-oxoprolinase (ATP-hydrolysing) 3.1489
TMEM39A transmembrane protein 39A 3.1365
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 3.1364
H1-0 H1.0 linker histone 3.1257
NPY5R neuropeptide Y receptor Y5 3.1093
OLFML3 olfactomedin-like 3 3.10785
RBKS ribokinase 3.105
DYNLT3 dynein, light chain, Tctex-type 3 3.1048
P3H1 prolyl 3-hydroxylase 1 3.0904
TXNDC15 thioredoxin domain containing 15 3.0874
RMDN1 regulator of microtubule dynamics 1 3.0842
EGR1 early growth response 1 3.08165
OARD1 O-acyl-ADP-ribose deacylase 1 3.0771
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 3.0708
DENND2D DENN/MADD domain containing 2D 3.05505
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 3.0388
ZCCHC8 zinc finger, CCHC domain containing 8 3.03835
ARMCX3 armadillo repeat containing, X-linked 3 3.03745
HSPA13 heat shock protein 70kDa family, member 13 3.02938
SQSTM1 sequestosome 1 3.0287
ODR4 odr-4 GPCR localization factor homolog 3.02295
INHBE inhibin, beta E 3.0185
WDR13 WD repeat domain 13 3.0111
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 2.9839
GALE UDP-galactose-4-epimerase 2.9807
AXIN1 axin 1 2.96155
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2.95955
TM9SF3 transmembrane 9 superfamily member 3 2.9501
COG5 component of oligomeric golgi complex 5 2.94692
IL1A interleukin 1, alpha 2.93775
USO1 USO1 vesicle transport factor 2.93705
PGM3 phosphoglucomutase 3 2.93558
LRP10 low density lipoprotein receptor-related protein 10 2.92545
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.9241
FICD FIC domain containing 2.9189
SIAH2 siah E3 ubiquitin protein ligase 2 2.91615
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.90585
AGTPBP1 ATP/GTP binding protein 1 2.9041
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 2.90265
HBA1 hemoglobin, alpha 1 2.89486
MID1IP1 MID1 interacting protein 1 2.8935
UNC5B unc-5 homolog B (C. elegans) 2.88855
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.887
COL5A2 collagen, type V, alpha 2 2.8752
ATRAID all-trans retinoic acid-induced differentiation factor 2.86265
HBEGF heparin-binding EGF-like growth factor 2.85425
TERF2IP telomeric repeat binding factor 2, interacting protein 2.8528
CLIC4 chloride intracellular channel 4 2.84603
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 2.84455
ZMYM2 zinc finger, MYM-type 2 2.8316
PDIA4 protein disulfide isomerase family A, member 4 2.8286
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 2.82135
ACSS3 acyl-CoA synthetase short-chain family member 3 2.8172
BCL2L2 BCL2-like 2 2.8154
SEC61B Sec61 beta subunit 2.81295
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.80063
PCCB propionyl CoA carboxylase, beta polypeptide 2.79795
NGLY1 N-glycanase 1 2.79735
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 2.78523
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.7834
KIZ kizuna centrosomal protein 2.7823
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.778
ATXN2 ataxin 2 2.7769
COPG1 coatomer protein complex, subunit gamma 1 2.7739
TTC17 tetratricopeptide repeat domain 17 2.76945
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.76345
IER3 immediate early response 3 2.75825
ZFAND1 zinc finger, AN1-type domain 1 2.75745
HAX1 HCLS1 associated protein X-1 2.75505
MYDGF myeloid-derived growth factor 2.74935
RPN2 ribophorin II 2.74755
TRIP12 thyroid hormone receptor interactor 12 2.74715
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 2.74385
PTS 6-pyruvoyltetrahydropterin synthase 2.7436
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.741
LIN7A lin-7 homolog A (C. elegans) 2.7399
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.73765
NRBF2 nuclear receptor binding factor 2 2.73345
TJP1 tight junction protein 1 2.7236
DGKD diacylglycerol kinase, delta 130kDa 2.7161
RHOF ras homolog family member F (in filopodia) 2.715
AMZ2 archaelysin family metallopeptidase 2 2.70805
IFRD1 interferon-related developmental regulator 1 2.70175
KLHDC2 kelch domain containing 2 2.70045
NGRN neugrin, neurite outgrowth associated 2.6977
RNF220 ring finger protein 220 2.697
NIT1 nitrilase 1 2.69655
ACVR1 activin A receptor, type I 2.6917
PLAUR plasminogen activator, urokinase receptor 2.69022
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.6827
MEAF6 MYST/Esa1-associated factor 6 2.6667
STN1 STN1 subunit of CST complex 2.6623
GTPBP2 GTP binding protein 2 2.662
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 2.6552
ITGAV integrin, alpha V 2.65035
NNMT nicotinamide N-methyltransferase 2.64882
HDAC4 histone deacetylase 4 2.6426
SMIM10L1 small integral membrane protein 10 like 1 2.6424
LMO4 LIM domain only 4 2.64055
MAP1B microtubule-associated protein 1B 2.6382
TMEM258 transmembrane protein 258 2.6381
PDIA6 protein disulfide isomerase family A, member 6 2.6355
RIOK3 RIO kinase 3 2.63405
USP11 ubiquitin specific peptidase 11 2.63125
MMP24-AS1-EDEM2 MMP24-AS1-EDEM2 readthrough 2.62715
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.6231
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.609
SUCO SUN domain containing ossification factor 2.6054
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.58655
NUPR1 nuclear protein, transcriptional regulator, 1 2.57985
IARS1 isoleucyl-tRNA synthetase 1 2.57605
AGA aspartylglucosaminidase 2.57532
PIPOX pipecolic acid oxidase 2.57265
ERP29 endoplasmic reticulum protein 29 2.5696
BLVRB biliverdin reductase B 2.56625
SEC24A SEC24 family member A 2.56607
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 2.565
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 2.56332
SEC31A SEC31 homolog A (S. cerevisiae) 2.5627
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.5615
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.55335
TWF2 twinfilin actin binding protein 2 2.54565
APLNR apelin receptor 2.5394
TTC4 tetratricopeptide repeat domain 4 2.53625
IRS1 insulin receptor substrate 1 2.5362
MAGED2 melanoma antigen family D2 2.53597
PRSS23 protease, serine, 23 2.52525
TSG101 tumor susceptibility 101 2.5213
CADM1 cell adhesion molecule 1 2.5211
SIK3 SIK family kinase 3 2.52063
UFL1 UFM1-specific ligase 1 2.51855
CALCOCO2 calcium binding and coiled-coil domain 2 2.51795
ETNPPL ethanolamine-phosphate phospho-lyase 2.51675
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 2.5163
WARS1 tryptophanyl-tRNA synthetase 1 2.5127
TAGLN transgelin 2.51153
NPIPB5 nuclear pore complex interacting protein family, member B5 2.5054
NPY1R neuropeptide Y receptor Y1 2.5037
PREPL prolyl endopeptidase-like 2.50352
LOC124907782 dual specificity protein phosphatase 22 2.4959
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.48925
WDR19 WD repeat domain 19 2.4871
INTS3 integrator complex subunit 3 2.48105
PTX3 pentraxin 3, long 2.48105
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 2.47965
CAMTA2 calmodulin binding transcription activator 2 2.4783
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2.47745
IQCB1 IQ motif containing B1 2.47288
GOLGA3 golgin A3 2.46965
ATXN1 ataxin 1 2.4651
TMEM59 transmembrane protein 59 2.4644
NDEL1 nudE neurodevelopment protein 1-like 1 2.4613
AOX1 aldehyde oxidase 1 2.46115
CDPF1 cysteine-rich, DPF motif domain containing 1 2.45805
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.4527
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.45255
S100P S100 calcium binding protein P 2.4525
GNG5 guanine nucleotide binding protein (G protein), gamma 5 2.44815
STXBP1 syntaxin binding protein 1 2.44225
OSGIN1 oxidative stress induced growth inhibitor 1 2.4291
MAP2K1 mitogen-activated protein kinase kinase 1 2.42125
ZNF516 zinc finger protein 516 2.4212
ERCC1 excision repair cross-complementation group 1 2.41808
RASAL2 RAS protein activator like 2 2.4179
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 2.40718
MEX3C mex-3 RNA binding family member C 2.40365
TGIF1 TGFB-induced factor homeobox 1 2.40215
CCDC90B coiled-coil domain containing 90B 2.3999
PDIA5 protein disulfide isomerase family A, member 5 2.399
STUM stum, mechanosensory transduction mediator homolog 2.39215
G0S2 G0/G1 switch 2 2.3907
ARMCX6 armadillo repeat containing, X-linked 6 2.38965
BABAM2 BRISC and BRCA1 A complex member 2 2.38855
UPP1 uridine phosphorylase 1 2.38685
HDLBP high density lipoprotein binding protein 2.3863
ALAS1 5'-aminolevulinate synthase 1 2.3852
VRK2 vaccinia related kinase 2 2.37825
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.3766
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.3736
P4HB prolyl 4-hydroxylase, beta polypeptide 2.372
LIF leukemia inhibitory factor 2.3689
STEAP1 six transmembrane epithelial antigen of the prostate 1 2.3657
PPIC peptidylprolyl isomerase C (cyclophilin C) 2.36513
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 2.3588
MSLN mesothelin 2.3548
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.35415
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.35225
CDC73 cell division cycle 73 2.34635
LOC114841035 uncharacterized LOC114841035 2.34385
PHF20L1 PHD finger protein 20-like 1 2.34375
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 2.3435
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.34055
TSC22D1 TSC22 domain family, member 1 2.33955
EFL1 elongation factor like GTPase 1 2.3329
KLHL12 kelch-like family member 12 2.3298
PKP1 plakophilin 1 2.32847
NFE2L1 nuclear factor, erythroid 2-like 1 2.32675
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 2.32328
NUP58 nucleoporin 58 2.3221
DNAAF11 dynein axonemal assembly factor 11 2.31915
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 2.31805
CTBS chitobiase, di-N-acetyl- 2.31687
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 2.3165
LOC102724560 cystathionine beta-synthase 2.3158
ANO1 anoctamin 1, calcium activated chloride channel 2.3149
NANS N-acetylneuraminic acid synthase 2.30515
METRN meteorin, glial cell differentiation regulator 2.3018
SARAF store-operated calcium entry-associated regulatory factor 2.29875
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.29565
MICU2 mitochondrial calcium uptake 2 2.2945
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 2.2944
OGDHL oxoglutarate dehydrogenase-like 2.29355
CST4 cystatin S 2.2934
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.2931
PLD3 phospholipase D family, member 3 2.2927
EGR3 early growth response 3 2.291
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.29085
SYNE3 spectrin repeat containing, nuclear envelope family member 3 2.2904
F7 coagulation factor VII (serum prothrombin conversion accelerator) 2.28965
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 2.2881
CRELD1 cysteine-rich with EGF-like domains 1 2.28635
KCMF1 potassium channel modulatory factor 1 2.2814
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2.281
TRIM8 tripartite motif containing 8 2.2794
LAMC2 laminin, gamma 2 2.27172
GFUS GDP-L-fucose synthase 2.2713
DDR2 discoidin domain receptor tyrosine kinase 2 2.2684
TRIB1 tribbles pseudokinase 1 2.26495
SPRY4 sprouty homolog 4 (Drosophila) 2.26465
ITM2C integral membrane protein 2C 2.2626
CST2 cystatin SA 2.2622
FNDC3A fibronectin type III domain containing 3A 2.25122
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 2.24895
SLC67A1 solute carrier family 67 member 1 2.24715
CTSW cathepsin W 2.2463
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.24465
EMILIN1 elastin microfibril interfacer 1 2.23975
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.239
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.2385
SCAF8 SR-related CTD-associated factor 8 2.23685
TMEM185B transmembrane protein 185B 2.2316
CLTC clathrin, heavy chain (Hc) 2.23095
STX18 syntaxin 18 2.2254
CHPF chondroitin polymerizing factor 2.22335
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.22195
MED8 mediator complex subunit 8 2.21938
LAD1 ladinin 1 2.21645
ICAM2 intercellular adhesion molecule 2 2.2147
CDK8 cyclin-dependent kinase 8 2.2109
WBP4 WW domain binding protein 4 2.20783
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 2.20286
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 2.20165
CST3 cystatin C 2.2015
NTM neurotrimin 2.20005
SEC24D SEC24 family member D 2.19618
GCC2 GRIP and coiled-coil domain containing 2 2.19565
LOC124907090 ankyrin repeat domain-containing protein SOWAHC-like 2.1895
PECR peroxisomal trans-2-enoyl-CoA reductase 2.1887
MTO1 mitochondrial tRNA translation optimization 1 2.18415
ARHGAP5 Rho GTPase activating protein 5 2.18265
ECD ecdysoneless homolog (Drosophila) 2.1807
ANXA5 annexin A5 2.1794
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.17645
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 2.1749
RCOR3 REST corepressor 3 2.17315
CCDC59 coiled-coil domain containing 59 2.1719
SPG11 spastic paraplegia 11 (autosomal recessive) 2.1716
ATF3 activating transcription factor 3 2.171
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 2.1694
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.1558
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.15412
PRAF2 PRA1 domain family, member 2 2.15235
CDCP1 CUB domain containing protein 1 2.1523
CD99 CD99 molecule 2.15197
UNC50 unc-50 homolog (C. elegans) 2.15195
TESC tescalcin 2.15125
OSBP oxysterol binding protein 2.14937
CDC37L1 cell division cycle 37-like 1 2.1488
CTAGE8 CTAGE family, member 8 2.14815
DRC9 dynein regulatory complex subunit 9 2.14815
TBL1X transducin (beta)-like 1X-linked 2.14569
GALK2 galactokinase 2 2.14297
FOXO4 forkhead box O4 2.14265
CORO1C coronin, actin binding protein, 1C 2.1349
CANX calnexin 2.13382
MARCHF3 membrane associated ring-CH-type finger 3 2.1317
ACOT9 acyl-CoA thioesterase 9 2.12845
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 2.1279
YIPF2 Yip1 domain family, member 2 2.12722
MXRA5 matrix-remodelling associated 5 2.1272
RAP1GAP2 RAP1 GTPase activating protein 2 2.12585
CIRBP cold inducible RNA binding protein 2.11658
FES FES proto-oncogene, tyrosine kinase 2.1163
CUL7 cullin 7 2.1139
DET1 de-etiolated homolog 1 (Arabidopsis) 2.1086
THY1 Thy-1 cell surface antigen 2.1079
NBAS neuroblastoma amplified sequence 2.10775
RIOX2 ribosomal oxygenase 2 2.10738
ATG13 autophagy related 13 2.10675
MAGED1 melanoma antigen family D1 2.10595
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.1002
GFPT2 glutamine-fructose-6-phosphate transaminase 2 2.09945
EPHA2 EPH receptor A2 2.0991
MTARC2 mitochondrial amidoxime reducing component 2 2.09702
BBOF1 basal body orientation factor 1 2.09665
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.0926
MTIF2 mitochondrial translational initiation factor 2 2.0923
CXCL3 chemokine (C-X-C motif) ligand 3 2.0832
SNX6 sorting nexin 6 2.08045
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.08013
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.0799
IFT20 intraflagellar transport 20 2.07875
RWDD2A RWD domain containing 2A 2.0727
CFP complement factor properdin 2.07235
MTMR6 myotubularin related protein 6 2.07175
TFF1 trefoil factor 1 2.0705
CCPG1 cell cycle progression 1 2.067
JMJD1C jumonji domain containing 1C 2.0649
PPIB peptidylprolyl isomerase B (cyclophilin B) 2.0637
RBM7 RNA binding motif protein 7 2.06325
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 2.06257
TFF2 trefoil factor 2 2.0599
SH2D2A SH2 domain containing 2A 2.05785
TFF3 trefoil factor 3 (intestinal) 2.0559
ZDHHC14 zinc finger, DHHC-type containing 14 2.05355
TRIP4 thyroid hormone receptor interactor 4 2.0456
CKAP4 cytoskeleton-associated protein 4 2.04517
CLDND1 claudin domain containing 1 2.04285
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.04205
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.0415
MYH9 myosin, heavy chain 9, non-muscle 2.03925
PGAP6 post-GPI attachment to proteins 6 2.0391
IDUA iduronidase, alpha-L- 2.03568
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 2.0355
THADA thyroid adenoma associated 2.03513
METTL1 methyltransferase like 1 2.0317
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 2.03152
PPARG peroxisome proliferator-activated receptor gamma 2.0297
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.0262
RABAC1 Rab acceptor 1 (prenylated) 2.02285
CREB5 cAMP responsive element binding protein 5 2.0225
NPDC1 neural proliferation, differentiation and control, 1 2.0222
IRF7 interferon regulatory factor 7 2.02135
RCN1 reticulocalbin 1, EF-hand calcium binding domain 2.0145
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 2.01375
SSR4 signal sequence receptor, delta 2.012
EIF1 eukaryotic translation initiation factor 1 2.00922
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 2.00833
SKIC2 SKI2 subunit of superkiller complex 2.00805
CDK5RAP3 CDK5 regulatory subunit associated protein 3 2.00515
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 2.00207
PALLD palladin, cytoskeletal associated protein 2.00193
CDK17 cyclin-dependent kinase 17 2.00047

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -8.97445
STMN1 stathmin 1 -8.4161
PCNA proliferating cell nuclear antigen -7.92595
OAT ornithine aminotransferase -7.88815
PLK1 polo-like kinase 1 -7.87755
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -7.39165
DCK deoxycytidine kinase -6.8113
CDC45 cell division cycle 45 -6.76765
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -6.01565
HMG20B high mobility group 20B -5.84132
HOXA5 homeobox A5 -5.8328
SMNDC1 survival motor neuron domain containing 1 -5.74545
SGK1 serum/glucocorticoid regulated kinase 1 -5.7298
TMEM109 transmembrane protein 109 -5.67785
ASF1B anti-silencing function 1B histone chaperone -5.53855
GINS2 GINS complex subunit 2 (Psf2 homolog) -5.3313
MCM7 minichromosome maintenance complex component 7 -5.20563
MCM10 minichromosome maintenance complex component 10 -5.1947
PSRC1 proline/serine-rich coiled-coil 1 -5.1174
MCM6 minichromosome maintenance complex component 6 -4.9811
GINS3 GINS complex subunit 3 (Psf3 homolog) -4.97895
CHAF1A chromatin assembly factor 1, subunit A (p150) -4.92695
UBE2C ubiquitin-conjugating enzyme E2C -4.9097
TKT transketolase -4.7023
CDK2 cyclin-dependent kinase 2 -4.68357
HSPB1 heat shock 27kDa protein 1 -4.6637
FEN1 flap structure-specific endonuclease 1 -4.60955
KIF20A kinesin family member 20A -4.5205
MCM3 minichromosome maintenance complex component 3 -4.47615
BIRC5 baculoviral IAP repeat containing 5 -4.43382
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -4.4316
CDK1 cyclin-dependent kinase 1 -4.43075
KIF11 kinesin family member 11 -4.4234
MCM5 minichromosome maintenance complex component 5 -4.41407
NASP nuclear autoantigenic sperm protein (histone-binding) -4.4017
TK1 thymidine kinase 1, soluble -4.29085
C1QBP complement component 1, q subcomponent binding protein -4.27847
CCNA2 cyclin A2 -4.26425
RRM1 ribonucleotide reductase M1 -4.19508
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -4.1932
SNRPA small nuclear ribonucleoprotein polypeptide A -4.17155
CRYZ crystallin, zeta (quinone reductase) -4.1105
BRCA1 breast cancer 1, early onset -4.07583
S100A4 S100 calcium binding protein A4 -3.9873
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.9714
PRR15L proline rich 15-like -3.96125
MCM4 minichromosome maintenance complex component 4 -3.94318
TRAP1 TNF receptor-associated protein 1 -3.93435
DHFR dihydrofolate reductase -3.9328
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -3.9265
CCNB1 cyclin B1 -3.92045
CD44 CD44 molecule (Indian blood group) -3.91663
CDC20 cell division cycle 20 -3.82335
RAD54L RAD54-like (S. cerevisiae) -3.8169
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.80992
CDT1 chromatin licensing and DNA replication factor 1 -3.80005
RFC3 replication factor C (activator 1) 3, 38kDa -3.79815
ZDHHC6 zinc finger, DHHC-type containing 6 -3.7784
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.77395
CCNF cyclin F -3.74463
CBR3 carbonyl reductase 3 -3.72395
PMM2 phosphomannomutase 2 -3.68735
CD320 CD320 molecule -3.68295
CHAF1B chromatin assembly factor 1, subunit B (p60) -3.6806
CENPM centromere protein M -3.67515
ZWINT ZW10 interacting kinetochore protein -3.66155
YME1L1 YME1-like 1 ATPase -3.65632
MCMBP minichromosome maintenance complex binding protein -3.65145
BID BH3 interacting domain death agonist -3.63377
WDR76 WD repeat domain 76 -3.63115
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.6251
GEMIN4 gem (nuclear organelle) associated protein 4 -3.61555
NUP85 nucleoporin 85kDa -3.6116
HSPA14 heat shock 70kDa protein 14 -3.6073
SESN1 sestrin 1 -3.59075
LAPTM4B lysosomal protein transmembrane 4 beta -3.58433
AURKB aurora kinase B -3.57765
BAG3 BCL2-associated athanogene 3 -3.5694
ERCC6L excision repair cross-complementation group 6-like -3.5502
AKT1 v-akt murine thymoma viral oncogene homolog 1 -3.54165
BZW2 basic leucine zipper and W2 domains 2 -3.51875
ANGPTL7 angiopoietin-like 7 -3.4975
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -3.4951
PRPF31 pre-mRNA processing factor 31 -3.47183
PCLAF PCNA clamp associated factor -3.46718
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.4399
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -3.4369
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.36175
CCNB2 cyclin B2 -3.34895
MT1X metallothionein 1X -3.34008
NUSAP1 nucleolar and spindle associated protein 1 -3.3377
TRAIP TRAF interacting protein -3.33225
KIF22 kinesin family member 22 -3.32075
JAG2 jagged 2 -3.31823
ACYP1 acylphosphatase 1, erythrocyte (common) type -3.3065
GMNN geminin, DNA replication inhibitor -3.29673
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.29365
CPNE3 copine III -3.27275
E2F1 E2F transcription factor 1 -3.26927
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -3.2692
NOTCH1 notch 1 -3.2683
TLCD3A TLC domain containing 3A -3.2638
TSPAN6 tetraspanin 6 -3.25583
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.2489
HELLS helicase, lymphoid-specific -3.23805
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -3.23655
ELOVL6 ELOVL fatty acid elongase 6 -3.22725
CROT carnitine O-octanoyltransferase -3.2135
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -3.19865
YJU2 YJU2 splicing factor homolog -3.18965
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.1874
KIF18B kinesin family member 18B -3.18345
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.1824
XPO7 exportin 7 -3.1817
MSH2 mutS homolog 2 -3.17965
FMNL3 formin-like 3 -3.17655
ARID4B AT rich interactive domain 4B (RBP1-like) -3.1671
ADRB2 adrenoceptor beta 2, surface -3.1628
SMC4 structural maintenance of chromosomes 4 -3.15168
EMP2 epithelial membrane protein 2 -3.1511
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.1476
PRPF4 pre-mRNA processing factor 4 -3.13235
ELAC2 elaC ribonuclease Z 2 -3.13175
OIP5 Opa interacting protein 5 -3.10605
SRSF2 serine/arginine-rich splicing factor 2 -3.10345
ANKRD10 ankyrin repeat domain 10 -3.10325
GJD3 gap junction protein, delta 3, 31.9kDa -3.0982
LMNB1 lamin B1 -3.0867
DCAF15 DDB1 and CUL4 associated factor 15 -3.06617
CCNE2 cyclin E2 -3.06502
MRM3 mitochondrial rRNA methyltransferase 3 -3.05915
DNM1 dynamin 1 -3.0588
BACE2 beta-site APP-cleaving enzyme 2 -3.0586
FBL fibrillarin -3.0581
UBAC1 UBA domain containing 1 -3.057
HADH hydroxyacyl-CoA dehydrogenase -3.05558
EFNA4 ephrin-A4 -3.0472
DSN1 DSN1, MIS12 kinetochore complex component -3.04645
ALDOC aldolase C, fructose-bisphosphate -3.04605
KIF14 kinesin family member 14 -3.03885
TMEM255A transmembrane protein 255A -3.037
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.0224
THOP1 thimet oligopeptidase 1 -3.01965
CENPX centromere protein X -3.01965
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -3.0181
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -3.0093
TRIP13 thyroid hormone receptor interactor 13 -3.007
KIF15 kinesin family member 15 -2.9982
MAB21L1 mab-21-like 1 (C. elegans) -2.98485
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.96753
DTX2 deltex 2, E3 ubiquitin ligase -2.96395
CASP8AP2 caspase 8 associated protein 2 -2.9623
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.94205
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.9361
PGAM4 phosphoglycerate mutase family member 4 -2.9274
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.92023
RFC2 replication factor C (activator 1) 2, 40kDa -2.9168
TYRP1 tyrosinase-related protein 1 -2.90025
FHL5 four and a half LIM domains 5 -2.89685
RANGAP1 Ran GTPase activating protein 1 -2.89635
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -2.8827
GPS1 G protein pathway suppressor 1 -2.8785
PALB2 partner and localizer of BRCA2 -2.87755
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.87705
DNA2 DNA replication helicase/nuclease 2 -2.86225
DSCC1 DNA replication and sister chromatid cohesion 1 -2.8509
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.8448
KLHDC3 kelch domain containing 3 -2.83655
ARHGAP11A Rho GTPase activating protein 11A -2.836
PA2G4 proliferation-associated 2G4, 38kDa -2.83525
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -2.83355
TFDP1 transcription factor Dp-1 -2.82835
NUP62 nucleoporin 62kDa -2.82385
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.8232
TROAP trophinin associated protein -2.8193
GTSE1 G-2 and S-phase expressed 1 -2.81483
PYDC1 PYD (pyrin domain) containing 1 -2.81355
PVALB parvalbumin -2.8035
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.79885
KRT13 keratin 13, type I -2.7984
PIMREG PICALM interacting mitotic regulator -2.79745
IVL involucrin -2.79435
SYNJ2BP synaptojanin 2 binding protein -2.79395
MT2A metallothionein 2A -2.79245
TMPO thymopoietin -2.79218
SRRT serrate, RNA effector molecule -2.78876
ZNF813 zinc finger protein 813 -2.7734
MYBBP1A MYB binding protein (P160) 1a -2.7547
SIVA1 SIVA1, apoptosis-inducing factor -2.7515
KIF18A kinesin family member 18A -2.75115
CDCA8 cell division cycle associated 8 -2.74185
TOP2A topoisomerase (DNA) II alpha 170kDa -2.73802
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -2.73235
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.7162
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.7161
WNT7B wingless-type MMTV integration site family, member 7B -2.7019
DCTPP1 dCTP pyrophosphatase 1 -2.70135
FOXM1 forkhead box M1 -2.69725
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.69645
TRIM22 tripartite motif containing 22 -2.6907
EXO1 exonuclease 1 -2.6866
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.68625
CAND2 cullin-associated and neddylation-dissociated 2 (putative) -2.68525
NUP93 nucleoporin 93kDa -2.68485
MIS18A MIS18 kinetochore protein A -2.6846
CA9 carbonic anhydrase IX -2.6845
BARD1 BRCA1 associated RING domain 1 -2.68385
TTF1 transcription termination factor, RNA polymerase I -2.68303
TMEM160 transmembrane protein 160 -2.6784
ADAMDEC1 ADAM-like, decysin 1 -2.67585
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.67197
TUBA3C tubulin, alpha 3c -2.6712
TEDC2 tubulin epsilon and delta complex 2 -2.66865
ARHGAP8 Rho GTPase activating protein 8 -2.66685
DUOX1 dual oxidase 1 -2.6611
QSER1 glutamine and serine rich 1 -2.65875
SOCS5 suppressor of cytokine signaling 5 -2.65832
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -2.6578
SPC25 SPC25, NDC80 kinetochore complex component -2.65425
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.6525
DUT deoxyuridine triphosphatase -2.65138
CBX3 chromobox homolog 3 -2.64757
PRKCD protein kinase C, delta -2.6445
PARPBP PARP1 binding protein -2.64185
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -2.64071
ATAD5 ATPase family, AAA domain containing 5 -2.63975
CHEK1 checkpoint kinase 1 -2.635
CAV2 caveolin 2 -2.63468
TUBGCP4 tubulin, gamma complex associated protein 4 -2.6333
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.6305
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -2.62965
NAP1L4 nucleosome assembly protein 1-like 4 -2.6221
INCENP inner centromere protein antigens 135/155kDa -2.62135
CLCA2 chloride channel accessory 2 -2.62024
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.61825
UNG uracil-DNA glycosylase -2.61035
FANCG Fanconi anemia, complementation group G -2.61015
NUP205 nucleoporin 205kDa -2.607
METTL16 methyltransferase like 16 -2.59135
WRAP53 WD repeat containing, antisense to TP53 -2.58707
NELFCD negative elongation factor complex member C/D -2.5846
TMEM51 transmembrane protein 51 -2.5797
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.57865
TRIM21 tripartite motif containing 21 -2.57265
NT5DC2 5'-nucleotidase domain containing 2 -2.57085
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.56655
MTA2 metastasis associated 1 family, member 2 -2.55915
NCAPH non-SMC condensin I complex, subunit H -2.5552
NYNRIN NYN domain and retroviral integrase containing -2.54775
ZNF324B zinc finger protein 324B -2.53785
SHPK sedoheptulokinase -2.53555
PFKM phosphofructokinase, muscle -2.53475
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.53347
CENPB centromere protein B, 80kDa -2.5322
TUBA4A tubulin, alpha 4a -2.53
POU2F1 POU class 2 homeobox 1 -2.52645
MKI67 marker of proliferation Ki-67 -2.52386
ARHGAP15 Rho GTPase activating protein 15 -2.5205
AMDHD2 amidohydrolase domain containing 2 -2.5175
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.5143
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.5139
RBL1 retinoblastoma-like 1 -2.5132
CCDC25 coiled-coil domain containing 25 -2.51305
CHURC1-FNTB CHURC1-FNTB readthrough -2.51025
KDM1A lysine (K)-specific demethylase 1A -2.5102
DCT dopachrome tautomerase -2.5021
NEK2 NIMA-related kinase 2 -2.50087
TBRG4 transforming growth factor beta regulator 4 -2.49855
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.49325
GYS1 glycogen synthase 1 (muscle) -2.4914
PBK PDZ binding kinase -2.4854
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -2.48425
MLANA melan-A -2.48298
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.48195
SLC26A6 solute carrier family 26 (anion exchanger), member 6 -2.481
DEAF1 DEAF1 transcription factor -2.48095
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.48085
CCND3 cyclin D3 -2.4797
PRR7 proline rich 7 (synaptic) -2.4785
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.47785
PBX3 pre-B-cell leukemia homeobox 3 -2.4776
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.4744
RPA3 replication protein A3, 14kDa -2.4715
CADM4 cell adhesion molecule 4 -2.4675
LPL lipoprotein lipase -2.46312
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -2.46205
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -2.45598
RFWD3 ring finger and WD repeat domain 3 -2.4518
CAV1 caveolin 1, caveolae protein, 22kDa -2.45
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -2.4488
TIMELESS timeless circadian clock -2.44737
CLNS1A chloride channel, nucleotide-sensitive, 1A -2.4463
SNX7 sorting nexin 7 -2.43835
FAM32A family with sequence similarity 32, member A -2.43725
TWNK twinkle mtDNA helicase -2.4357
CCN3 cellular communication network factor 3 -2.43455
PADI3 peptidyl arginine deiminase, type III -2.4344
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.43385
CDC25A cell division cycle 25A -2.4337
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type -2.43324
HROB homologous recombination factor with OB-fold -2.43105
PRMT7 protein arginine methyltransferase 7 -2.4237
ATAD2 ATPase family, AAA domain containing 2 -2.4236
CASP1 caspase 1, apoptosis-related cysteine peptidase -2.41969
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.4165
HACL2 2-hydroxyacyl-CoA lyase 2 -2.4153
HIP1 huntingtin interacting protein 1 -2.41038
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.4094
PRCC papillary renal cell carcinoma (translocation-associated) -2.40515
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -2.40395
MTA1 metastasis associated 1 -2.39152
CENPI centromere protein I -2.39132
PGRMC1 progesterone receptor membrane component 1 -2.39057
PGP phosphoglycolate phosphatase -2.38565
SRSF3 serine/arginine-rich splicing factor 3 -2.38455
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -2.37821
ARMC7 armadillo repeat containing 7 -2.3776
JPT2 Jupiter microtubule associated homolog 2 -2.3745
PHTF2 putative homeodomain transcription factor 2 -2.3744
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.3717
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.36735
AIRE autoimmune regulator -2.36165
BTBD2 BTB (POZ) domain containing 2 -2.35695
CD81 CD81 molecule -2.35685
MORC3 MORC family CW-type zinc finger 3 -2.3552
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.35502
AURKA aurora kinase A -2.34993
WDR62 WD repeat domain 62 -2.33835
TUBA1B tubulin, alpha 1b -2.3382
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.3381
PMPCA peptidase (mitochondrial processing) alpha -2.3372
VBP1 von Hippel-Lindau binding protein 1 -2.3306
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.3285
TCOF1 Treacher Collins-Franceschetti syndrome 1 -2.32838
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.32415
HPS6 Hermansky-Pudlak syndrome 6 -2.32185
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.31805
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.31385
DEPDC1 DEP domain containing 1 -2.3123
CORO1A coronin, actin binding protein, 1A -2.31175
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.30918
UBAP2L ubiquitin associated protein 2-like -2.30744
RRP1B ribosomal RNA processing 1B -2.3067
CBX1 chromobox homolog 1 -2.3026
ARHGAP22 Rho GTPase activating protein 22 -2.30255
HAT1 histone acetyltransferase 1 -2.3003
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.2975
BCKDK branched chain ketoacid dehydrogenase kinase -2.29095
CNOT3 CCR4-NOT transcription complex, subunit 3 -2.29047
SMIM8 small integral membrane protein 8 -2.28573
SEPHS1 selenophosphate synthetase 1 -2.2851
MYOZ3 myozenin 3 -2.2841
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.2838
NCAPG2 non-SMC condensin II complex, subunit G2 -2.28315
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.28215
FAT2 FAT atypical cadherin 2 -2.28195
UNC119 unc-119 homolog (C. elegans) -2.2787
H1-10 H1.10 linker histone -2.27775
VAV3 vav 3 guanine nucleotide exchange factor -2.2766
NCAPD3 non-SMC condensin II complex, subunit D3 -2.2744
AGGF1 angiogenic factor with G patch and FHA domains 1 -2.2708
DEF8 differentially expressed in FDCP 8 homolog (mouse) -2.26805
FANCI Fanconi anemia, complementation group I -2.26545
MSH6 mutS homolog 6 -2.26147
RMI1 RecQ mediated genome instability 1 -2.25995
TCERG1 transcription elongation regulator 1 -2.25495
PRODH proline dehydrogenase (oxidase) 1 -2.24735
CDC25C cell division cycle 25C -2.24598
BORCS8 BLOC-1 related complex subunit 8 -2.24295
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) -2.24065
TUBB tubulin, beta class I -2.24014
PRPF8 pre-mRNA processing factor 8 -2.2387
TTK TTK protein kinase -2.2387
CISD1 CDGSH iron sulfur domain 1 -2.2374
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -2.23685
SPINK5 serine peptidase inhibitor, Kazal type 5 -2.2367
SUZ12 SUZ12 polycomb repressive complex 2 subunit -2.23042
CUL1 cullin 1 -2.22655
HAUS7 HAUS augmin-like complex, subunit 7 -2.22625
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.22615
TUBA3E tubulin, alpha 3e -2.2257
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) -2.22425
IPO9 importin 9 -2.22197
RAD51 RAD51 recombinase -2.22048
MAP3K11 mitogen-activated protein kinase kinase kinase 11 -2.21985
RNF38 ring finger protein 38 -2.2195
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.2193
MRPS2 mitochondrial ribosomal protein S2 -2.218
ADISSP adipose secreted signaling protein -2.2175
INTS9 integrator complex subunit 9 -2.21655
TRIP6 thyroid hormone receptor interactor 6 -2.2151
POLK polymerase (DNA directed) kappa -2.2115
ABHD17A abhydrolase domain containing 17A -2.20905
MAB21L4 mab-21 like 4 -2.20655
KIF4A kinesin family member 4A -2.20565
FGFR3 fibroblast growth factor receptor 3 -2.20385
PHACTR1 phosphatase and actin regulator 1 -2.20335
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.20258
SNRPE small nuclear ribonucleoprotein polypeptide E -2.1929
GJA8 gap junction protein, alpha 8, 50kDa -2.1919
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -2.19135
DNM2 dynamin 2 -2.1905
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.19045
CENPC centromere protein C -2.1899
CDKN2AIP CDKN2A interacting protein -2.1881
RABL6 RAB, member RAS oncogene family-like 6 -2.1853
PGAM2 phosphoglycerate mutase 2 (muscle) -2.18505
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -2.1828
DEFA3 defensin, alpha 3, neutrophil-specific -2.18205
ADI1 acireductone dioxygenase 1 -2.182
KIFC1 kinesin family member C1 -2.17955
ATF5 activating transcription factor 5 -2.17692
HSPA8 heat shock 70kDa protein 8 -2.17638
U2AF2 U2 small nuclear RNA auxiliary factor 2 -2.17515
METTL2A methyltransferase like 2A -2.17423
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -2.17415
PLN phospholamban -2.17413
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.1738
NUP160 nucleoporin 160kDa -2.17372
TYMS thymidylate synthetase -2.1737
CEP131 centrosomal protein 131kDa -2.1726
PARD3 par-3 family cell polarity regulator -2.17188
IKZF4 IKAROS family zinc finger 4 (Eos) -2.1713
CCDC86 coiled-coil domain containing 86 -2.1674
TMEM14A transmembrane protein 14A -2.1618
HMGB2 high mobility group box 2 -2.15895
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -2.15745
MRPL12 mitochondrial ribosomal protein L12 -2.15135
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.14647
GFOD2 glucose-fructose oxidoreductase domain containing 2 -2.14565
DNASE1 deoxyribonuclease I -2.14565
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.14265
MRPL11 mitochondrial ribosomal protein L11 -2.1422
MDC1 mediator of DNA-damage checkpoint 1 -2.14062
NCAPD2 non-SMC condensin I complex, subunit D2 -2.14035
ASB13 ankyrin repeat and SOCS box containing 13 -2.13915
USP2 ubiquitin specific peptidase 2 -2.13895
MAB21L2 mab-21-like 2 (C. elegans) -2.1373
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -2.1357
CINP cyclin-dependent kinase 2 interacting protein -2.1349
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -2.13383
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -2.12945
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -2.1276
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -2.12503
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.1247
LRP3 low density lipoprotein receptor-related protein 3 -2.12385
ZNF219 zinc finger protein 219 -2.12375
SLC66A2 solute carrier family 66 member 2 -2.12065
PRICKLE3 prickle homolog 3 (Drosophila) -2.11815
BICD2 bicaudal D homolog 2 (Drosophila) -2.11668
TCEA2 transcription elongation factor A (SII), 2 -2.11625
KRT4 keratin 4, type II -2.11265
E2F2 E2F transcription factor 2 -2.11105
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -2.1106
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -2.10825
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.1067
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.10535
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.10518
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.1036
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -2.10245
MVP major vault protein -2.10135
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.10015
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.0982
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -2.09775
THEM6 thioesterase superfamily member 6 -2.0974
VRK1 vaccinia related kinase 1 -2.09675
PNLIPRP2 pancreatic lipase-related protein 2 -2.09615
DCAF7 DDB1 and CUL4 associated factor 7 -2.0953
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -2.0945
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -2.0926
CACTIN cactin, spliceosome C complex subunit -2.09082
HIRIP3 HIRA interacting protein 3 -2.0904
TAC4 tachykinin 4 (hemokinin) -2.0898
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein -2.08715
ZNF324 zinc finger protein 324 -2.08555
CLDN8 claudin 8 -2.08335
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.0826
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.0799
HSPA1A heat shock 70kDa protein 1A -2.0788
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -2.0782
TNNT3 troponin T type 3 (skeletal, fast) -2.07625
IPO8 importin 8 -2.07285
TNK1 tyrosine kinase, non-receptor, 1 -2.07235
RGS1 regulator of G-protein signaling 1 -2.0718
RACK1 receptor for activated C kinase 1 -2.07055
CTCF CCCTC-binding factor (zinc finger protein) -2.06835
HPS5 Hermansky-Pudlak syndrome 5 -2.068
CRABP2 cellular retinoic acid binding protein 2 -2.06515
SPHK2 sphingosine kinase 2 -2.06487
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -2.0629
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.062
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -2.06013
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 -2.05971
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -2.05855
SCNN1B sodium channel, non voltage gated 1 beta subunit -2.0563
ZBTB24 zinc finger and BTB domain containing 24 -2.0549
IGSF3 immunoglobulin superfamily, member 3 -2.0517
NEMP1 nuclear envelope integral membrane protein 1 -2.04782
SLC19A1 solute carrier family 19 (folate transporter), member 1 -2.04731
DHRS11 dehydrogenase/reductase (SDR family) member 11 -2.04575
PRKX protein kinase, X-linked -2.04562
SLBP stem-loop binding protein -2.04515
WEE1 WEE1 G2 checkpoint kinase -2.04465
CCDC81 coiled-coil domain containing 81 -2.0422
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 -2.04051
CEP55 centrosomal protein 55kDa -2.03615
TRMT5 tRNA methyltransferase 5 -2.0351
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -2.02825
CHP2 calcineurin-like EF-hand protein 2 -2.0282
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -2.02795
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 -2.027
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.02455
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.024
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.02203
ENTREP3 endosomal transmembrane epsin interactor 3 -2.021
HMGN2 high mobility group nucleosomal binding domain 2 -2.01895
SREK1IP1 SREK1-interacting protein 1 -2.01875
ILF2 interleukin enhancer binding factor 2 -2.01805
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -2.017
TPM3 tropomyosin 3 -2.01595
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.015
PTGER4 prostaglandin E receptor 4 (subtype EP4) -2.01443
VPS26C VPS26 endosomal protein sorting factor C -2.01213
GCG glucagon -2.0089
PGAP2 post-GPI attachment to proteins 2 -2.00865
CD59 CD59 molecule, complement regulatory protein -2.0084
ATRIP ATR interacting protein -2.00825
AMPD1 adenosine monophosphate deaminase 1 -2.0082
TUBB6 tubulin, beta 6 class V -2.0072
KPNB1 karyopherin (importin) beta 1 -2.00677
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.0067
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.0048
RBM8A RNA binding motif protein 8A -2.00469
CALM3 calmodulin 3 (phosphorylase kinase, delta) -2.00287