CRCGN017_MCF10A.WT.HP_24H:H13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzoin 100.46 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:H13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 3.9303
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.6623
KDM5D lysine (K)-specific demethylase 5D 3.27795
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.9439
FBXO7 F-box protein 7 2.589
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.51143
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.50628
TPD52L2 tumor protein D52-like 2 2.4085
RAB31 RAB31, member RAS oncogene family 2.35883
TATDN2 TatD DNase domain containing 2 2.282
LSR lipolysis stimulated lipoprotein receptor 2.2348
COQ8A coenzyme Q8A 2.0616

decreased expression

Symbol Name Standardized Value
C2CD5 C2 calcium-dependent domain containing 5 -4.9229
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -4.75815
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -4.4454
HMG20B high mobility group 20B -4.2884
SMC1A structural maintenance of chromosomes 1A -3.00338
RGS2 regulator of G-protein signaling 2 -2.99905
SGK1 serum/glucocorticoid regulated kinase 1 -2.9411
FAIM Fas apoptotic inhibitory molecule -2.8672
KDM5C lysine (K)-specific demethylase 5C -2.7622
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.5596
KDM6A lysine (K)-specific demethylase 6A -2.42845
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.3221
SNX7 sorting nexin 7 -2.2783
PUDP pseudouridine 5'-phosphatase -2.2673
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.22405
CORO2A coronin, actin binding protein, 2A -2.14385
TOMM70 translocase of outer mitochondrial membrane 70 -2.1099