| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benzoin 11.16 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
109 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:H15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 9.69585 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 5.77955 |
| STK10 | serine/threonine kinase 10 | 5.23452 |
| WIF1 | WNT inhibitory factor 1 | 5.0 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 4.92 |
| IDE | insulin-degrading enzyme | 4.50565 |
| AGR2 | anterior gradient 2 | 4.28215 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 3.19788 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.12748 |
| GRB10 | growth factor receptor-bound protein 10 | 3.0559 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 2.8887 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 2.8775 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 2.7533 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.66895 |
| FBXO11 | F-box protein 11 | 2.64768 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 2.59605 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.5579 |
| TMEM50B | transmembrane protein 50B | 2.5502 |
| NAP1L2 | nucleosome assembly protein 1-like 2 | 2.54095 |
| NSG2 | neuronal vesicle trafficking associated 2 | 2.50185 |
| SCG3 | secretogranin III | 2.41345 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 2.4022 |
| TFCP2 | transcription factor CP2 | 2.4005 |
| PCBP1 | poly(rC) binding protein 1 | 2.3615 |
| SYT1 | synaptotagmin I | 2.35505 |
| USP21 | ubiquitin specific peptidase 21 | 2.3288 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide | 2.31575 |
| IRX5 | iroquois homeobox 5 | 2.29285 |
| TRAM1 | translocation associated membrane protein 1 | 2.25845 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 | 2.24975 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | 2.2447 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 2.2393 |
| CRH | corticotropin releasing hormone | 2.2266 |
| UNC13B | unc-13 homolog B (C. elegans) | 2.2102 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 2.2083 |
| CLDN1 | claudin 1 | 2.1998 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated | 2.1534 |
| CST3 | cystatin C | 2.12825 |
| PLPBP | pyridoxal phosphate binding protein | 2.1172 |
| FXN | frataxin | 2.11035 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.107 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T | 2.1069 |
| ZNF207 | zinc finger protein 207 | 2.10065 |
| WBP11 | WW domain binding protein 11 | 2.086 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.08343 |
| CADM1 | cell adhesion molecule 1 | 2.07693 |
| BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor | 2.0761 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 2.072 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 2.06545 |
| ATP12A | ATPase, H+/K+ transporting, nongastric, alpha polypeptide | 2.05595 |
| RBKS | ribokinase | 2.05385 |
| PLPP1 | phospholipid phosphatase 1 | 2.04868 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B | 2.04015 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 2.03205 |
| INA | internexin neuronal intermediate filament protein, alpha | 2.02665 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.0142 |
| TRAF1 | TNF receptor-associated factor 1 | 2.00555 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 | 2.00525 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -5.211 |
| UFM1 | ubiquitin-fold modifier 1 | -5.12565 |
| S100A8 | S100 calcium binding protein A8 | -5.0 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.9181 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -4.8313 |
| CCNB2 | cyclin B2 | -4.51045 |
| HMG20B | high mobility group 20B | -4.46418 |
| KRT14 | keratin 14, type I | -3.84225 |
| MSMO1 | methylsterol monooxygenase 1 | -3.8267 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.5549 |
| WASHC4 | WASH complex subunit 4 | -3.42355 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -3.34937 |
| UBE3C | ubiquitin protein ligase E3C | -3.28065 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -3.1546 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -3.06085 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | -2.8755 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -2.78165 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -2.68245 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.56445 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | -2.4568 |
| MREG | melanoregulin | -2.32225 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | -2.3049 |
| ZFYVE26 | zinc finger, FYVE domain containing 26 | -2.30072 |
| TRPS1 | trichorhinophalangeal syndrome I | -2.2699 |
| NCBP3 | nuclear cap binding subunit 3 | -2.2581 |
| EIF2B2 | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | -2.25775 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -2.2148 |
| SETD3 | SET domain containing 3 | -2.2036 |
| SPIN2B | spindlin family, member 2B | -2.1911 |
| AMOTL2 | angiomotin like 2 | -2.1843 |
| VIPAS39 | VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog | -2.1833 |
| OXTR | oxytocin receptor | -2.1809 |
| SLC38A6 | solute carrier family 38, member 6 | -2.17425 |
| BCL10 | B-cell CLL/lymphoma 10 | -2.17185 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | -2.16585 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -2.15095 |
| TLCD3A | TLC domain containing 3A | -2.14865 |
| SLC35B1 | solute carrier family 35, member B1 | -2.1479 |
| DOCK6 | dedicator of cytokinesis 6 | -2.14605 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | -2.13025 |
| LY86 | lymphocyte antigen 86 | -2.09785 |
| DENND4C | DENN/MADD domain containing 4C | -2.0893 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | -2.08325 |
| BATF | basic leucine zipper transcription factor, ATF-like | -2.076 |
| ZNF528 | zinc finger protein 528 | -2.0754 |
| LCMT1 | leucine carboxyl methyltransferase 1 | -2.06705 |
| FIG4 | FIG4 phosphoinositide 5-phosphatase | -2.0564 |
| ZNF671 | zinc finger protein 671 | -2.0541 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -2.0502 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | -2.02115 |
| RRAGD | Ras-related GTP binding D | -2.019 |
