CRCGN017_MCF10A.WT.HP_24H:I02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-aminoazotoluene 33.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

46 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.55386
CASP10 caspase 10, apoptosis-related cysteine peptidase 3.16377
KCTD5 potassium channel tetramerization domain containing 5 2.86445
ACLY ATP citrate lyase 2.73548
FCHO1 FCH domain only 1 2.60649
LSR lipolysis stimulated lipoprotein receptor 2.57564
GIMAP6 GTPase, IMAP family member 6 2.51327
ADA2 adenosine deaminase 2 2.43041
GIMAP4 GTPase, IMAP family member 4 2.35398
NOL4 nucleolar protein 4 2.34227
GLRX glutaredoxin (thioltransferase) 2.32611
DUSP9 dual specificity phosphatase 9 2.21208
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 2.20608
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.1831
GIMAP5 GTPase, IMAP family member 5 2.16574
RNF144A ring finger protein 144A 2.16396
RNASE6 ribonuclease, RNase A family, k6 2.15627
TAPBPL TAP binding protein-like 2.13944
PECAM1 platelet/endothelial cell adhesion molecule 1 2.1271
UBASH3A ubiquitin associated and SH3 domain containing A 2.11826
ADAT1 adenosine deaminase, tRNA-specific 1 2.10851
TESPA1 thymocyte expressed, positive selection associated 1 2.10708
CADM1 cell adhesion molecule 1 2.08083
GAL3ST4 galactose-3-O-sulfotransferase 4 2.05717
CASP1 caspase 1, apoptosis-related cysteine peptidase 2.04635
DOK5 docking protein 5 2.03161
RASIP1 Ras interacting protein 1 2.00113
KCTD13 potassium channel tetramerization domain containing 13 2.00041

decreased expression

Symbol Name Standardized Value
CD81 CD81 molecule -5.60021
CDC45 cell division cycle 45 -4.27272
WASHC4 WASH complex subunit 4 -4.1428
CD58 CD58 molecule -3.94201
KRT14 keratin 14, type I -3.83565
CREG1 cellular repressor of E1A-stimulated genes 1 -3.70753
BASP1 brain abundant, membrane attached signal protein 1 -3.52626
ARID4B AT rich interactive domain 4B (RBP1-like) -3.52493
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.18428
TM9SF3 transmembrane 9 superfamily member 3 -3.17746
TCEA2 transcription elongation factor A (SII), 2 -2.9423
HOXA5 homeobox A5 -2.61156
REXO2 RNA exonuclease 2 -2.45496
MTCL1 microtubule crosslinking factor 1 -2.24796
EXOSC4 exosome component 4 -2.20479
PRKCZ protein kinase C, zeta -2.19953
SIAH2 siah E3 ubiquitin protein ligase 2 -2.13681
HSPB8 heat shock 22kDa protein 8 -2.03544