CRCGN017_MCF10A.WT.HP_24H:I04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isoniazid 100.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 4.50566
CXCR4 chemokine (C-X-C motif) receptor 4 4.50102
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.60997
LOXL1 lysyl oxidase-like 1 3.60339
TBPL1 TBP-like 1 2.72162
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.62713
CYTH1 cytohesin 1 2.18693
NOTCH1 notch 1 2.16121
RAB31 RAB31, member RAS oncogene family 2.1051

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -5.6645
ANKRD10 ankyrin repeat domain 10 -3.70901
NLRP4 NLR family, pyrin domain containing 4 -2.91669
SLC35B1 solute carrier family 35, member B1 -2.82968
MRPL12 mitochondrial ribosomal protein L12 -2.76413
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.69786
PLK1 polo-like kinase 1 -2.64372
CANT1 calcium activated nucleotidase 1 -2.59746
ACAA1 acetyl-CoA acyltransferase 1 -2.54909
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.35895
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.27435
CLCN5 chloride channel, voltage-sensitive 5 -2.02678
SCD5 stearoyl-CoA desaturase 5 -2.02093