CRCGN017_MCF10A.WT.HP_24H:I06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isoniazid 11.14 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 3.79458
SYK spleen tyrosine kinase 3.2359
SSBP2 single-stranded DNA binding protein 2 2.89679
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.85051
CCDC92 coiled-coil domain containing 92 2.63182
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.61859

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -5.55401
PCCB propionyl CoA carboxylase, beta polypeptide -3.64089
TXNDC9 thioredoxin domain containing 9 -3.08854
KRT14 keratin 14, type I -2.91165
YME1L1 YME1-like 1 ATPase -2.82389
HMG20B high mobility group 20B -2.76524
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.6792
TSPAN4 tetraspanin 4 -2.4866
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.48521
MSN moesin -2.29035
ARPP19 cAMP-regulated phosphoprotein, 19kDa -2.275
SPRED2 sprouty-related, EVH1 domain containing 2 -2.20017
RXYLT1 ribitol xylosyltransferase 1 -2.16037
TMEM135 transmembrane protein 135 -2.1224