CRCGN017_MCF10A.WT.HP_24H:I07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description roxarsone 99.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KLHL21 kelch-like family member 21 5.70345
ABHD4 abhydrolase domain containing 4 4.43565
FGFR4 fibroblast growth factor receptor 4 3.84732
BID BH3 interacting domain death agonist 3.71968
CCNA1 cyclin A1 3.35455
ACAA1 acetyl-CoA acyltransferase 1 3.272
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.85805
ACLY ATP citrate lyase 2.59802
ZNF318 zinc finger protein 318 2.2534
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.17843
CENPE centromere protein E, 312kDa 2.1337
MSRA methionine sulfoxide reductase A 2.07445

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -5.4091
CD320 CD320 molecule -4.86905
OXA1L oxidase (cytochrome c) assembly 1-like -4.86325
RALGDS ral guanine nucleotide dissociation stimulator -3.68
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.2429
EIF5 eukaryotic translation initiation factor 5 -2.88618
SNX7 sorting nexin 7 -2.867
MYLK myosin light chain kinase -2.3266
CORO1A coronin, actin binding protein, 1A -2.04265
GDF15 growth differentiation factor 15 -2.0216