| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | promethazine 11.2 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CNRIP1 | cannabinoid receptor interacting protein 1 | 5.4408 |
| CCDC92 | coiled-coil domain containing 92 | 5.4161 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.16645 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.61375 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.99183 |
| FZD7 | frizzled class receptor 7 | 3.80413 |
| FGFR4 | fibroblast growth factor receptor 4 | 3.49653 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.19055 |
| CCNF | cyclin F | 3.09985 |
| GRB10 | growth factor receptor-bound protein 10 | 2.86517 |
| TCTN1 | tectonic family member 1 | 2.84245 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.70725 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.6528 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.52527 |
| DSN1 | DSN1, MIS12 kinetochore complex component | 2.45385 |
| SP3 | Sp3 transcription factor | 2.44865 |
| PROS1 | protein S (alpha) | 2.31035 |
| GMPS | guanine monphosphate synthase | 2.2307 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 | 2.2072 |
| CPAP | centrosome assembly and centriole elongation protein | 2.158 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 2.1343 |
| RPH3A | rabphilin 3A | 2.1266 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | 2.09265 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 2.0684 |
| NSG2 | neuronal vesicle trafficking associated 2 | 2.06405 |
| TTI1 | TELO2 interacting protein 1 | 2.0241 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 2.02305 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 | 2.0139 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 2.0037 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -5.17965 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -5.0 |
| LAP3 | leucine aminopeptidase 3 | -4.9464 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -4.41825 |
| CD44 | CD44 molecule (Indian blood group) | -4.29319 |
| GDF15 | growth differentiation factor 15 | -3.64155 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -3.39248 |
| IRF8 | interferon regulatory factor 8 | -3.27735 |
| MSN | moesin | -3.1541 |
| ANXA2 | annexin A2 | -3.0379 |
| S100A4 | S100 calcium binding protein A4 | -2.86105 |
| MYCBP | MYC binding protein | -2.81388 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.75087 |
| XPO7 | exportin 7 | -2.62923 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -2.54005 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 | -2.5354 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -2.5197 |
| CCR2 | chemokine (C-C motif) receptor 2 | -2.46755 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -2.3335 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.33005 |
| APOL3 | apolipoprotein L, 3 | -2.26905 |
| RMDN3 | regulator of microtubule dynamics 3 | -2.2329 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -2.21465 |
| SNX7 | sorting nexin 7 | -2.21005 |
| SELENBP1 | selenium binding protein 1 | -2.1714 |
| DSE | dermatan sulfate epimerase | -2.17025 |
| IFRD2 | interferon-related developmental regulator 2 | -2.16913 |
| FBN1 | fibrillin 1 | -2.16368 |
| SLAMF7 | SLAM family member 7 | -2.11315 |
| SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 | -2.08575 |
| LPXN | leupaxin | -2.04995 |
| DGKA | diacylglycerol kinase, alpha 80kDa | -2.02562 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -2.01 |
