CRCGN017_MCF10A.WT.HP_24H:I15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description trans-cinnamaldehyde 11.2 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

36 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.1498
WIF1 WNT inhibitory factor 1 5.1125
CARMIL1 capping protein regulator and myosin 1 linker 1 4.8418
MAMLD1 mastermind-like domain containing 1 4.614
VGLL4 vestigial-like family member 4 4.0104
ACAA1 acetyl-CoA acyltransferase 1 3.17027
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.63055
APOE apolipoprotein E 2.25185
ABI1 abl-interactor 1 2.16432
ANO10 anoctamin 10 2.12805
SPTSSA serine palmitoyltransferase, small subunit A 2.07015
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 2.04965
WDR41 WD repeat domain 41 2.0183

decreased expression

Symbol Name Standardized Value
RPIA ribose 5-phosphate isomerase A -4.93585
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.5797
CREG1 cellular repressor of E1A-stimulated genes 1 -4.3766
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.9231
SORBS3 sorbin and SH3 domain containing 3 -3.63907
SGK1 serum/glucocorticoid regulated kinase 1 -3.1566
IFRD2 interferon-related developmental regulator 2 -3.11523
TMEM115 transmembrane protein 115 -2.6902
TAC4 tachykinin 4 (hemokinin) -2.63205
HEATR1 HEAT repeat containing 1 -2.626
RNF123 ring finger protein 123 -2.377
MYBPC2 myosin binding protein C, fast type -2.34825
KRT14 keratin 14, type I -2.16005
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -2.1477
FAT2 FAT atypical cadherin 2 -2.13465
GDF15 growth differentiation factor 15 -2.12905
PER3 period circadian clock 3 -2.10385
ANXA1 annexin A1 -2.08315
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -2.06525
FKTN fukutin -2.04765
CAPN15 calpain 15 -2.01345
LTA4H leukotriene A4 hydrolase -2.00315
PCBP1 poly(rC) binding protein 1 -2.0021