CRCGN017_MCF10A.WT.HP_24H:I19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tributyl phosphate 99.96 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

728 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 10.0
ADO 2-aminoethanethiol (cysteamine) dioxygenase 10.0
AGR2 anterior gradient 2 10.0
CXCL2 chemokine (C-X-C motif) ligand 2 10.0
AXIN1 axin 1 9.4049
HBA1 hemoglobin, alpha 1 7.14197
HBB hemoglobin, beta 6.94593
FZD7 frizzled class receptor 7 6.8495
CCL2 chemokine (C-C motif) ligand 2 6.6197
BLTP2 bridge-like lipid transfer protein family member 2 6.3866
CGRRF1 cell growth regulator with ring finger domain 1 5.565
NRBF2 nuclear receptor binding factor 2 5.3342
CXCL8 chemokine (C-X-C motif) ligand 8 4.83845
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 4.61967
CDCA4 cell division cycle associated 4 4.4333
MEX3C mex-3 RNA binding family member C 4.3769
RPN1 ribophorin I 4.2537
CXCL3 chemokine (C-X-C motif) ligand 3 4.0912
TDP1 tyrosyl-DNA phosphodiesterase 1 4.0078
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 3.8791
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 3.8777
ACTA2 actin, alpha 2, smooth muscle, aorta 3.8006
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 3.724
SYNE2 spectrin repeat containing, nuclear envelope 2 3.6296
RFX5 regulatory factor X, 5 (influences HLA class II expression) 3.57465
ARHGAP19 Rho GTPase activating protein 19 3.5435
HSPA8 heat shock 70kDa protein 8 3.48927
ETNK1 ethanolamine kinase 1 3.42695
VDAC1 voltage-dependent anion channel 1 3.34795
CXCL6 chemokine (C-X-C motif) ligand 6 3.3468
CRYZ crystallin, zeta (quinone reductase) 3.3015
CDC45 cell division cycle 45 3.2974
PRSS3 protease, serine, 3 3.2694
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 3.26185
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 3.26035
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 3.2497
EBNA1BP2 EBNA1 binding protein 2 3.2048
JAM2 junctional adhesion molecule 2 3.1611
NTM neurotrimin 3.1349
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 3.1256
LHFPL6 LHFPL tetraspan subfamily member 6 3.125
CST3 cystatin C 3.0962
ZMIZ1 zinc finger, MIZ-type containing 1 3.0891
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 3.0763
CNIH3 cornichon family AMPA receptor auxiliary protein 3 3.0555
DMAC2L distal membrane arm assembly component 2 like 3.04507
MATN2 matrilin 2 3.045
CERS1 ceramide synthase 1 3.0118
ALG11 ALG11, alpha-1,2-mannosyltransferase 3.0081
CTPS2 CTP synthase 2 3.0036
AOPEP aminopeptidase O (putative) 3.0012
CLEC11A C-type lectin domain family 11, member A 2.98187
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.979
TSPAN8 tetraspanin 8 2.9595
DCTPP1 dCTP pyrophosphatase 1 2.946
DZIP1 DAZ interacting zinc finger protein 1 2.94575
MED7 mediator complex subunit 7 2.94475
EXO1 exonuclease 1 2.9278
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 2.9234
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.9055
CRTC3 CREB regulated transcription coactivator 3 2.8945
HOXD11 homeobox D11 2.8775
RCOR3 REST corepressor 3 2.8657
NCAM2 neural cell adhesion molecule 2 2.838
ZW10 zw10 kinetochore protein 2.8331
ALDOC aldolase C, fructose-bisphosphate 2.817
LYPLA1 lysophospholipase I 2.81465
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.8038
TRIM32 tripartite motif containing 32 2.7891
NDP Norrie disease (pseudoglioma) 2.7883
HOMER1 homer scaffolding protein 1 2.7871
ZNF761 zinc finger protein 761 2.785
ATF5 activating transcription factor 5 2.7842
RBP1 retinol binding protein 1, cellular 2.7704
JRKL JRK-like 2.7569
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.7458
EPS8 epidermal growth factor receptor pathway substrate 8 2.7359
EGR3 early growth response 3 2.7182
PRR5L proline rich 5 like 2.7003
PPP1R3D protein phosphatase 1, regulatory subunit 3D 2.69995
RCOR1 REST corepressor 1 2.6983
LAMP5 lysosomal-associated membrane protein family, member 5 2.6983
CLDN5 claudin 5 2.6938
IGFBP4 insulin-like growth factor binding protein 4 2.6911
LAMA2 laminin, alpha 2 2.68897
POU3F2 POU class 3 homeobox 2 2.6876
SNUPN snurportin 1 2.6841
HOXD10 homeobox D10 2.6837
LIPG lipase, endothelial 2.6831
SUZ12 SUZ12 polycomb repressive complex 2 subunit 2.6829
HADH hydroxyacyl-CoA dehydrogenase 2.68257
WSB2 WD repeat and SOCS box containing 2 2.6818
MXRA7 matrix-remodelling associated 7 2.6704
NPY5R neuropeptide Y receptor Y5 2.6691
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.6635
SQOR sulfide quinone oxidoreductase 2.6565
NPY1R neuropeptide Y receptor Y1 2.6559
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 2.6491
PLCG1 phospholipase C, gamma 1 2.63695
NUBPL nucleotide binding protein-like 2.6364
TFRC transferrin receptor 2.6311
GATA4 GATA binding protein 4 2.6247
ZNF200 zinc finger protein 200 2.6228
UBXN2B UBX domain protein 2B 2.6218
GEMIN2 gem (nuclear organelle) associated protein 2 2.61613
FAM168A family with sequence similarity 168, member A 2.6116
CCNA1 cyclin A1 2.5976
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.5946
TEFM transcription elongation factor, mitochondrial 2.5783
SMYD2 SET and MYND domain containing 2 2.5667
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 2.56435
UBE2W ubiquitin-conjugating enzyme E2W (putative) 2.5622
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.5616
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 2.5567
S100A10 S100 calcium binding protein A10 2.5544
IL17RB interleukin 17 receptor B 2.5441
TERF2IP telomeric repeat binding factor 2, interacting protein 2.5386
ZFYVE21 zinc finger, FYVE domain containing 21 2.5374
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 2.5331
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 2.5281
BCL10 B-cell CLL/lymphoma 10 2.5253
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 2.5236
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.5174
GOLGA8A golgin A8 family, member A 2.5151
NBPF19 neuroblastoma breakpoint family, member 19 2.4964
PDLIM1 PDZ and LIM domain 1 2.4961
NEK3 NIMA-related kinase 3 2.49005
SNX19 sorting nexin 19 2.48805
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.4851
COX5A cytochrome c oxidase subunit Va 2.4844
CALM1 calmodulin 1 (phosphorylase kinase, delta) 2.47782
SLC44A1 solute carrier family 44 (choline transporter), member 1 2.4572
TMEM168 transmembrane protein 168 2.4566
SUSD6 sushi domain containing 6 2.4556
ASMTL acetylserotonin O-methyltransferase-like 2.45247
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.4502
EAPP E2F-associated phosphoprotein 2.449
CEP192 centrosomal protein 192kDa 2.4414
TRIL TLR4 interactor with leucine-rich repeats 2.43715
LMTK1 lemur tail kinase 1 2.434
LRRC49 leucine rich repeat containing 49 2.4319
GMFB glia maturation factor, beta 2.4217
LYRM1 LYR motif containing 1 2.4186
ZNF532 zinc finger protein 532 2.4162
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 2.40735
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 2.4053
MTFR1 mitochondrial fission regulator 1 2.405
TFDP1 transcription factor Dp-1 2.40215
MAPRE1 microtubule-associated protein, RP/EB family, member 1 2.39935
SPAG5 sperm associated antigen 5 2.3993
DACT1 dishevelled-binding antagonist of beta-catenin 1 2.3989
IFI27 interferon, alpha-inducible protein 27 2.3974
ADRA2A adrenoceptor alpha 2A 2.3956
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 2.394
NUP93 nucleoporin 93kDa 2.3878
FAR2 fatty acyl CoA reductase 2 2.3864
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.3843
MAPK6 mitogen-activated protein kinase 6 2.3762
HMGB3 high mobility group box 3 2.376
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 2.3576
CALCB calcitonin-related polypeptide beta 2.3421
ADGRG2 adhesion G protein-coupled receptor G2 2.3409
MTM1 myotubularin 1 2.33865
ASXL2 additional sex combs like transcriptional regulator 2 2.3383
RAMP1 receptor (G protein-coupled) activity modifying protein 1 2.3379
ZNF7 zinc finger protein 7 2.3319
SACS sacsin molecular chaperone 2.3307
ZNF432 zinc finger protein 432 2.3305
GLCE glucuronic acid epimerase 2.321
RPS26 ribosomal protein S26 2.3186
GABPB1 GA binding protein transcription factor, beta subunit 1 2.31595
ZNF365 zinc finger protein 365 2.3147
AGPS alkylglycerone phosphate synthase 2.3136
S100G S100 calcium binding protein G 2.3128
VWF von Willebrand factor 2.3093
PADI2 peptidyl arginine deiminase, type II 2.3088
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 2.30767
PRKCB protein kinase C, beta 2.30175
MACIR macrophage immunometabolism regulator 2.295
TBCCD1 TBCC domain containing 1 2.2905
ATP9A ATPase, class II, type 9A 2.2888
THAP1 THAP domain containing, apoptosis associated protein 1 2.2865
RAB40B RAB40B, member RAS oncogene family 2.2816
ZCCHC10 zinc finger, CCHC domain containing 10 2.2761
MAN2B2 mannosidase, alpha, class 2B, member 2 2.2738
SPACA9 sperm acrosome associated 9 2.2609
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 2.2595
VCPKMT valosin containing protein lysine (K) methyltransferase 2.2578
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 2.2526
ERN2 endoplasmic reticulum to nucleus signaling 2 2.2515
CBFB core-binding factor, beta subunit 2.24855
MAT2A methionine adenosyltransferase II, alpha 2.24705
PRSS2 protease, serine, 2 (trypsin 2) 2.24535
EPHB2 EPH receptor B2 2.24465
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.2438
CH25H cholesterol 25-hydroxylase 2.2418
PRPS2 phosphoribosyl pyrophosphate synthetase 2 2.2402
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 2.2356
PTPN9 protein tyrosine phosphatase, non-receptor type 9 2.2347
ENOPH1 enolase-phosphatase 1 2.2319
ZNF516 zinc finger protein 516 2.2302
TIPIN TIMELESS interacting protein 2.2299
ZEB2 zinc finger E-box binding homeobox 2 2.2265
BACE1 beta-site APP-cleaving enzyme 1 2.2209
ATG3 autophagy related 3 2.2207
SPATA2L spermatogenesis associated 2-like 2.2155
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 2.2115
MACROH2A1 macroH2A.1 histone 2.20997
NR2F6 nuclear receptor subfamily 2, group F, member 6 2.2098
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 2.2068
CKMT1A creatine kinase, mitochondrial 1A 2.2035
MAPK13 mitogen-activated protein kinase 13 2.20205
CD99 CD99 molecule 2.1991
GTF2H2C GTF2H2 family member C 2.1946
RUVBL1 RuvB-like AAA ATPase 1 2.1934
FAM222B family with sequence similarity 222, member B 2.1933
FCGRT Fc fragment of IgG, receptor, transporter, alpha 2.1932
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 2.1879
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 2.1869
RBM6 RNA binding motif protein 6 2.185
BPIFA1 BPI fold containing family A, member 1 2.1849
MYL12B myosin, light chain 12B, regulatory 2.1835
WASF2 WAS protein family, member 2 2.1806
TM9SF3 transmembrane 9 superfamily member 3 2.1775
CDKN3 cyclin-dependent kinase inhibitor 3 2.1768
MSL1 male-specific lethal 1 homolog (Drosophila) 2.1761
THAP10 THAP domain containing 10 2.1757
BCAR3 breast cancer anti-estrogen resistance 3 2.1731
GID8 GID complex subunit 8 2.1721
SOBP sine oculis binding protein homolog (Drosophila) 2.1703
CKAP2 cytoskeleton associated protein 2 2.1702
LMO2 LIM domain only 2 (rhombotin-like 1) 2.1635
NPM3 nucleophosmin/nucleoplasmin 3 2.1552
TENT5A terminal nucleotidyltransferase 5A 2.1536
ZNF410 zinc finger protein 410 2.15185
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 2.14725
EXD2 exonuclease 3'-5' domain containing 2 2.1458
RBBP7 retinoblastoma binding protein 7 2.1438
MVB12B multivesicular body subunit 12B 2.13623
FKTN fukutin 2.1342
RPP40 ribonuclease P/MRP 40kDa subunit 2.134
IL1RAP interleukin 1 receptor accessory protein 2.12865
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 2.1219
RBMX2 RNA binding motif protein, X-linked 2 2.11865
CHL1 cell adhesion molecule L1-like 2.1134
NUTF2 nuclear transport factor 2 2.1099
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 2.1053
SERF1A small EDRK-rich factor 1A (telomeric) 2.1049
SDF2 stromal cell-derived factor 2 2.1048
FERMT1 fermitin family member 1 2.103
SYNGAP1 synaptic Ras GTPase activating protein 1 2.09665
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.0951
SYCP2 synaptonemal complex protein 2 2.09127
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.0911
ZNF16 zinc finger protein 16 2.0886
RAB4A RAB4A, member RAS oncogene family 2.0874
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.0857
DUSP3 dual specificity phosphatase 3 2.08523
LAMB1 laminin, beta 1 2.08265
CPZ carboxypeptidase Z 2.0812
TXNL4B thioredoxin-like 4B 2.073
MGP matrix Gla protein 2.0692
STN1 STN1 subunit of CST complex 2.0655
ZNF415 zinc finger protein 415 2.0637
GPHN gephyrin 2.0607
TUBGCP5 tubulin, gamma complex associated protein 5 2.0601
CALML4 calmodulin-like 4 2.0593
ELOF1 elongation factor 1 homolog (S. cerevisiae) 2.0576
HOXB9 homeobox B9 2.0473
FLRT2 fibronectin leucine rich transmembrane protein 2 2.0438
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.0417
LGI1 leucine-rich, glioma inactivated 1 2.0407
RAB22A RAB22A, member RAS oncogene family 2.03975
CEP76 centrosomal protein 76kDa 2.0361
DCTN5 dynactin 5 (p25) 2.03565
NBPF10 neuroblastoma breakpoint family, member 10 2.0348
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 2.0306
ZNF536 zinc finger protein 536 2.0304
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.0294
FAM53C family with sequence similarity 53, member C 2.0278
THSD1 thrombospondin, type I, domain containing 1 2.026
NRN1 neuritin 1 2.0241
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 2.0139
NKAPD1 NKAP domain containing 1 2.0122
DPEP1 dipeptidase 1 (renal) 2.0119
TFCP2L1 transcription factor CP2-like 1 2.0116
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 2.0049
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.0044
CTSC cathepsin C 2.0029
MIDEAS mitotic deacetylase associated SANT domain protein 2.0009

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -10.0
YME1L1 YME1-like 1 ATPase -9.14697
HMG20B high mobility group 20B -9.05225
CD44 CD44 molecule (Indian blood group) -8.33854
TRAPPC3 trafficking protein particle complex 3 -7.71345
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -6.1556
CREG1 cellular repressor of E1A-stimulated genes 1 -5.9317
WASHC4 WASH complex subunit 4 -4.71923
SMC4 structural maintenance of chromosomes 4 -4.71527
TRAP1 TNF receptor-associated protein 1 -4.7112
RPA3 replication protein A3, 14kDa -4.5211
MT2A metallothionein 2A -4.3606
TUBA4A tubulin, alpha 4a -4.0793
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -3.873
CASC3 cancer susceptibility candidate 3 -3.8658
TMEM39B transmembrane protein 39B -3.8612
ACOT13 acyl-CoA thioesterase 13 -3.8231
DIPK1A divergent protein kinase domain 1A -3.81295
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 -3.7889
MSN moesin -3.7566
DCTD dCMP deaminase -3.68923
SLC38A10 solute carrier family 38, member 10 -3.6868
CACTIN cactin, spliceosome C complex subunit -3.64073
CASD1 CAS1 domain containing 1 -3.5687
ZNF76 zinc finger protein 76 -3.5607
MOGS mannosyl-oligosaccharide glucosidase -3.5488
FASTK Fas-activated serine/threonine kinase -3.54493
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -3.4456
NUP133 nucleoporin 133kDa -3.4388
TGM3 transglutaminase 3 -3.4135
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -3.39753
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -3.3839
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 -3.3616
MRPS15 mitochondrial ribosomal protein S15 -3.3341
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -3.3274
CLDN9 claudin 9 -3.2665
NME6 NME/NM23 nucleoside diphosphate kinase 6 -3.2577
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -3.25705
UCN urocortin -3.2396
DNM2 dynamin 2 -3.2382
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -3.2373
MTMR14 myotubularin related protein 14 -3.2345
RPAP1 RNA polymerase II associated protein 1 -3.203
CMTR1 cap methyltransferase 1 -3.19
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -3.1683
KTN1 kinectin 1 (kinesin receptor) -3.16727
CDC34 cell division cycle 34 -3.1547
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -3.1417
TXNRD1 thioredoxin reductase 1 -3.117
GAST gastrin -3.1096
CUL1 cullin 1 -3.098
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -3.0914
SP8 Sp8 transcription factor -3.0662
CDSN corneodesmosin -3.05865
SIRT6 sirtuin 6 -3.0361
TFE3 transcription factor binding to IGHM enhancer 3 -3.023
CLTC clathrin, heavy chain (Hc) -3.0204
TMEM45A transmembrane protein 45A -3.0195
GRAPL GRB2-related adaptor protein-like -3.0066
MEAF6 MYST/Esa1-associated factor 6 -3.0047
SF3A3 splicing factor 3a, subunit 3, 60kDa -3.0003
GAL3ST4 galactose-3-O-sulfotransferase 4 -2.9952
DCTN1 dynactin 1 -2.98665
USP19 ubiquitin specific peptidase 19 -2.983
ENO3 enolase 3 (beta, muscle) -2.9766
ANGPTL3 angiopoietin-like 3 -2.9766
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -2.9518
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -2.95055
SNPH syntaphilin -2.9478
ZNF91 zinc finger protein 91 -2.9477
TSPAN12 tetraspanin 12 -2.9455
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -2.9422
RSU1 Ras suppressor protein 1 -2.9335
IPO13 importin 13 -2.923
PCYOX1 prenylcysteine oxidase 1 -2.9193
ALG12 ALG12, alpha-1,6-mannosyltransferase -2.9173
TCHH trichohyalin -2.8977
EPHX2 epoxide hydrolase 2, cytoplasmic -2.8968
SMG9 SMG9 nonsense mediated mRNA decay factor -2.8882
AGO3 argonaute RISC catalytic component 3 -2.8808
FHIT fragile histidine triad -2.8561
SGPP2 sphingosine-1-phosphate phosphatase 2 -2.8506
RAX retina and anterior neural fold homeobox -2.8482
NOP10 NOP10 ribonucleoprotein -2.8462
CSPG4 chondroitin sulfate proteoglycan 4 -2.8345
SMC6 structural maintenance of chromosomes 6 -2.8327
LTN1 listerin E3 ubiquitin protein ligase 1 -2.8249
TRPM2 transient receptor potential cation channel, subfamily M, member 2 -2.8218
KRT76 keratin 76, type II -2.8158
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.8151
SPTBN4 spectrin, beta, non-erythrocytic 4 -2.8149
MFSD12 major facilitator superfamily domain containing 12 -2.8138
KIAA0319L KIAA0319-like -2.8126
ERBIN erbb2 interacting protein -2.8039
BHMT2 betaine--homocysteine S-methyltransferase 2 -2.8016
MAP7D1 MAP7 domain containing 1 -2.7954
CYBRD1 cytochrome b reductase 1 -2.7939
BHMT betaine--homocysteine S-methyltransferase -2.7915
PFKM phosphofructokinase, muscle -2.776
FOLR3 folate receptor 3 (gamma) -2.7675
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -2.7648
CXXC4 CXXC finger protein 4 -2.7646
TPSD1 tryptase delta 1 -2.7636
CALY calcyon neuron-specific vesicular protein -2.7581
PFN1 profilin 1 -2.7546
HLA-DMA major histocompatibility complex, class II, DM alpha -2.7399
DRG2 developmentally regulated GTP binding protein 2 -2.7233
ACBD4 acyl-CoA binding domain containing 4 -2.7222
TMEM131L transmembrane 131 like -2.7207
APOF apolipoprotein F -2.7187
REXO2 RNA exonuclease 2 -2.71448
OSBPL10 oxysterol binding protein-like 10 -2.704
PBX3 pre-B-cell leukemia homeobox 3 -2.704
CRELD1 cysteine-rich with EGF-like domains 1 -2.7025
TESPA1 thymocyte expressed, positive selection associated 1 -2.683
MZB1 marginal zone B and B1 cell-specific protein -2.6801
HOXC13 homeobox C13 -2.6668
ICAM1 intercellular adhesion molecule 1 -2.663
XPC xeroderma pigmentosum, complementation group C -2.6571
CLDN6 claudin 6 -2.6561
LYPD3 LY6/PLAUR domain containing 3 -2.6454
YTHDC1 YTH domain containing 1 -2.6447
HBE1 hemoglobin, epsilon 1 -2.6425
NAPSA napsin A aspartic peptidase -2.64
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -2.6335
ACAD10 acyl-CoA dehydrogenase family, member 10 -2.6322
LMBR1L limb development membrane protein 1-like -2.6268
EPHB6 EPH receptor B6 -2.6265
LIM2 lens intrinsic membrane protein 2, 19kDa -2.6251
ORAI3 ORAI calcium release-activated calcium modulator 3 -2.6241
ZNF574 zinc finger protein 574 -2.6195
GSTM2 glutathione S-transferase mu 2 (muscle) -2.6174
PIAS4 protein inhibitor of activated STAT, 4 -2.61625
CNKSR1 connector enhancer of kinase suppressor of Ras 1 -2.6139
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -2.611
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -2.6096
EBI3 Epstein-Barr virus induced 3 -2.6068
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -2.6063
AXL AXL receptor tyrosine kinase -2.60285
ACVR2B activin A receptor, type IIB -2.5889
UNC50 unc-50 homolog (C. elegans) -2.5865
TMEM59L transmembrane protein 59-like -2.5853
IL36A interleukin 36, alpha -2.5771
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -2.5765
CLPTM1 cleft lip and palate associated transmembrane protein 1 -2.57345
NISCH nischarin -2.5653
SLC39A1 solute carrier family 39 (zinc transporter), member 1 -2.5627
HPN hepsin -2.5613
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.5563
SCFD1 sec1 family domain containing 1 -2.5542
THOP1 thimet oligopeptidase 1 -2.5525
VPS35L VPS35 endosomal protein sorting factor like -2.5471
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -2.5379
VAC14 Vac14 homolog (S. cerevisiae) -2.5374
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -2.5363
PMM1 phosphomannomutase 1 -2.5354
F13B coagulation factor XIII, B polypeptide -2.5339
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -2.5259
CNGA1 cyclic nucleotide gated channel alpha 1 -2.5232
NOCT nocturnin -2.5201
CSDC2 cold shock domain containing C2, RNA binding -2.5185
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -2.5167
KRT6A keratin 6A, type II -2.5163
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.5042
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -2.5008
CEP70 centrosomal protein 70kDa -2.4994
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -2.49935
RAD50 RAD50 homolog (S. cerevisiae) -2.4987
AAAS achalasia, adrenocortical insufficiency, alacrimia -2.4983
ATG7 autophagy related 7 -2.4895
ADORA2A adenosine A2a receptor -2.4828
MAGT1 magnesium transporter 1 -2.4769
ZNF580 zinc finger protein 580 -2.4755
MTA1 metastasis associated 1 -2.47
RIC8A RIC8 guanine nucleotide exchange factor A -2.4644
S100A7 S100 calcium binding protein A7 -2.463
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 -2.4619
S100A3 S100 calcium binding protein A3 -2.4594
NPPA natriuretic peptide A -2.4484
CPLX3 complexin 3 -2.4471
LYPLA2 lysophospholipase II -2.44657
PFDN1 prefoldin subunit 1 -2.4434
NUP205 nucleoporin 205kDa -2.4426
MUTYH mutY homolog -2.4378
FGF6 fibroblast growth factor 6 -2.4369
FMO3 flavin containing monooxygenase 3 -2.4343
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.43127
C4A complement component 4A (Rodgers blood group) -2.4167
RAB3B RAB3B, member RAS oncogene family -2.41665
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 -2.4134
EYA3 EYA transcriptional coactivator and phosphatase 3 -2.4095
MINK1 misshapen-like kinase 1 -2.4093
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.4075
KRT9 keratin 9, type I -2.407
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -2.40405
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -2.4018
CHPF2 chondroitin polymerizing factor 2 -2.3997
NQO2 NAD(P)H dehydrogenase, quinone 2 -2.3978
CDK5 cyclin-dependent kinase 5 -2.3911
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -2.3911
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -2.3832
TRPM8 transient receptor potential cation channel, subfamily M, member 8 -2.3832
L1CAM L1 cell adhesion molecule -2.3831
UPB1 ureidopropionase, beta -2.3811
SIX6 SIX homeobox 6 -2.3777
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 -2.3728
RND3 Rho family GTPase 3 -2.3714
AKR1C4 aldo-keto reductase family 1, member C4 -2.37
TRMT61A tRNA methyltransferase 61A -2.3695
WAC WW domain containing adaptor with coiled-coil -2.36765
PSRC1 proline/serine-rich coiled-coil 1 -2.3667
LMO1 LIM domain only 1 (rhombotin 1) -2.366
OTC ornithine carbamoyltransferase -2.3655
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 -2.36368
LY6G5C lymphocyte antigen 6 complex, locus G5C -2.3602
CAMKV CaM kinase-like vesicle-associated -2.3564
ACSM5 acyl-CoA synthetase medium-chain family member 5 -2.35465
CRHBP corticotropin releasing hormone binding protein -2.3537
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.3519
ULK1 unc-51 like autophagy activating kinase 1 -2.3516
HTRA2 HtrA serine peptidase 2 -2.35125
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -2.3496
LECT2 leukocyte cell-derived chemotaxin 2 -2.3491
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -2.3478
TRPV5 transient receptor potential cation channel, subfamily V, member 5 -2.3473
USO1 USO1 vesicle transport factor -2.3471
KRT16 keratin 16, type I -2.3443
UBL5 ubiquitin-like 5 -2.344
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -2.3435
COL9A2 collagen, type IX, alpha 2 -2.3427
PIEZO1 piezo-type mechanosensitive ion channel component 1 -2.3424
CASP8 caspase 8, apoptosis-related cysteine peptidase -2.34175
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.3377
PERP PERP, TP53 apoptosis effector -2.3329
RUSF1 RUS family member 1 -2.3318
PCNT pericentrin -2.3318
METTL25B methyltransferase like 25B -2.3303
ACSM2A acyl-CoA synthetase medium-chain family member 2A -2.3291
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -2.3288
DRAM1 DNA-damage regulated autophagy modulator 1 -2.3282
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -2.3263
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 -2.3216
P4HB prolyl 4-hydroxylase, beta polypeptide -2.3167
ANGPTL4 angiopoietin-like 4 -2.3148
HSPB6 heat shock protein, alpha-crystallin-related, B6 -2.312
PSORS1C2 psoriasis susceptibility 1 candidate 2 -2.3111
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -2.31015
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.305
TDO2 tryptophan 2,3-dioxygenase -2.3024
BARX1 BARX homeobox 1 -2.2987
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 -2.2962
GDF2 growth differentiation factor 2 -2.2954
MYH9 myosin, heavy chain 9, non-muscle -2.294
BAAT bile acid CoA:amino acid N-acyltransferase -2.2897
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 -2.28875
EREG epiregulin -2.2882
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 -2.2847
COQ8A coenzyme Q8A -2.281
TLE5 TLE family member 5, transcriptional modulator -2.2804
SHBG sex hormone-binding globulin -2.2798
TADA3 transcriptional adaptor 3 -2.2781
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -2.2777
MLF2 myeloid leukemia factor 2 -2.2777
FBXO3 F-box protein 3 -2.2776
DCHS1 dachsous cadherin-related 1 -2.27305
ERV3-1-ZNF117 ERV3-1-ZNF117 readthrough -2.2719
TRAFD1 TRAF-type zinc finger domain containing 1 -2.26965
BECN1 beclin 1, autophagy related -2.26935
LRRC31 leucine rich repeat containing 31 -2.2684
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 -2.2682
ACTC1 actin, alpha, cardiac muscle 1 -2.2657
CENPC centromere protein C -2.2612
LRRN2 leucine rich repeat neuronal 2 -2.2603
KLK14 kallikrein-related peptidase 14 -2.2599
PRSS53 protease, serine, 53 -2.2593
FAM149A family with sequence similarity 149, member A -2.25737
EEF2 eukaryotic translation elongation factor 2 -2.2534
CUL7 cullin 7 -2.25295
CYP3A7-CYP3A51P CYP3A7-CYP3A51P readthrough -2.2526
EVPL envoplakin -2.2487
COPE coatomer protein complex, subunit epsilon -2.24775
FBXO46 F-box protein 46 -2.243
DAZAP1 DAZ associated protein 1 -2.2422
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.2414
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 -2.2409
PCSK2 proprotein convertase subtilisin/kexin type 2 -2.24035
RDH16 retinol dehydrogenase 16 (all-trans) -2.2397
ZNF750 zinc finger protein 750 -2.2393
ABI1 abl-interactor 1 -2.23815
TENM3 teneurin transmembrane protein 3 -2.237
LCE2B late cornified envelope 2B -2.2369
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -2.2369
PRPF8 pre-mRNA processing factor 8 -2.2322
CLSTN3 calsyntenin 3 -2.2316
H2BC5 H2B clustered histone 5 -2.2284
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.225
ECHDC3 enoyl CoA hydratase domain containing 3 -2.2243
TMEM158 transmembrane protein 158 (gene/pseudogene) -2.2227
GYPC glycophorin C (Gerbich blood group) -2.2214
ALOX12B arachidonate 12-lipoxygenase, 12R type -2.2209
GDF5 growth differentiation factor 5 -2.2183
PMM2 phosphomannomutase 2 -2.2181
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.2128
H1-2 H1.2 linker histone, cluster member -2.2106
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 -2.2073
PPP1R13L protein phosphatase 1, regulatory subunit 13 like -2.2064
PRSS16 protease, serine, 16 (thymus) -2.2026
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -2.2001
MYT1 myelin transcription factor 1 -2.1986
FAM174B family with sequence similarity 174, member B -2.1974
MRPL44 mitochondrial ribosomal protein L44 -2.1962
TGM1 transglutaminase 1 -2.196
DENND5A DENN/MADD domain containing 5A -2.1916
SNX2 sorting nexin 2 -2.18835
MASP2 mannan-binding lectin serine peptidase 2 -2.18813
CCDC86 coiled-coil domain containing 86 -2.1864
SLC17A2 solute carrier family 17, member 2 -2.1863
CFHR3 complement factor H-related 3 -2.1857
GPR162 G protein-coupled receptor 162 -2.1817
SH3GL2 SH3-domain GRB2-like 2 -2.1779
URGCP upregulator of cell proliferation -2.1759
RNF115 ring finger protein 115 -2.1702
HOXB3 homeobox B3 -2.1696
AFM afamin -2.169
HPX hemopexin -2.16875
NT5DC3 5'-nucleotidase domain containing 3 -2.1685
HSF4 heat shock transcription factor 4 -2.1684
MNX1 motor neuron and pancreas homeobox 1 -2.1675
NMT2 N-myristoyltransferase 2 -2.1667
PHF1 PHD finger protein 1 -2.16625
CLIP1 CAP-GLY domain containing linker protein 1 -2.16575
ECSIT ECSIT signalling integrator -2.1575
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 -2.1571
KPLCE KPRP N-terminal and LCE C-terminal like protein -2.1554
SCGB1D2 secretoglobin, family 1D, member 2 -2.155
NOL11 nucleolar protein 11 -2.153
DMPK dystrophia myotonica-protein kinase -2.1506
CDC37 cell division cycle 37 -2.148
KLHDC3 kelch domain containing 3 -2.14745
GLI3 GLI family zinc finger 3 -2.1474
TUBA8 tubulin, alpha 8 -2.1455
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 -2.1413
ESRP2 epithelial splicing regulatory protein 2 -2.1361
DOHH deoxyhypusine hydroxylase/monooxygenase -2.1298
ZNF671 zinc finger protein 671 -2.1297
DLK2 delta-like 2 homolog (Drosophila) -2.1261
PTPRN protein tyrosine phosphatase, receptor type, N -2.1257
CEP170B centrosomal protein 170B -2.1217
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 -2.1198
AADAC arylacetamide deacetylase -2.1141
SMIM44 small integral membrane protein 44 -2.11275
TPRA1 transmembrane protein, adipocyte asscociated 1 -2.1109
AGO1 argonaute RISC catalytic component 1 -2.1086
FOXE1 forkhead box E1 -2.1053
TRIM13 tripartite motif containing 13 -2.1036
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.1028
CNTLN centlein, centrosomal protein -2.1015
CALCOCO1 calcium binding and coiled-coil domain 1 -2.0968
FOSL1 FOS-like antigen 1 -2.0928
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 -2.0909
POU2AF1 POU class 2 associating factor 1 -2.088
AIRIM AFG2 interacting ribosome maturation factor -2.0862
OARD1 O-acyl-ADP-ribose deacylase 1 -2.0836
SSX3 synovial sarcoma, X breakpoint 3 -2.0836
TBX5 T-box 5 -2.08355
SOD1 superoxide dismutase 1, soluble -2.0835
ZNF430 zinc finger protein 430 -2.083
AARS1 alanyl-tRNA synthetase 1 -2.0828
NCDN neurochondrin -2.0825
F12 coagulation factor XII (Hageman factor) -2.08205
PPL periplakin -2.079
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) -2.0787
OTOR otoraplin -2.0785
APOL3 apolipoprotein L, 3 -2.0777
IFT57 intraflagellar transport 57 -2.0775
GCLC glutamate-cysteine ligase, catalytic subunit -2.07545
ADGRE1 adhesion G protein-coupled receptor E1 -2.0736
KPTN kaptin (actin binding protein) -2.0692
ADIPOR1 adiponectin receptor 1 -2.0689
CIC capicua transcriptional repressor -2.0676
GYS2 glycogen synthase 2 (liver) -2.0672
BDKRB1 bradykinin receptor B1 -2.0669
JADE1 jade family PHD finger 1 -2.0658
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -2.0619
GATA2 GATA binding protein 2 -2.0617
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 -2.05575
RPLP2 ribosomal protein, large, P2 -2.0556
CPM carboxypeptidase M -2.0556
UFSP2 UFM1-specific peptidase 2 -2.0533
FTSJ3 FtsJ homolog 3 (E. coli) -2.0531
OSMR oncostatin M receptor -2.05
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.0489
GPATCH3 G patch domain containing 3 -2.0468
DMAC2 distal membrane arm assembly component 2 -2.044
FABP6 fatty acid binding protein 6, ileal -2.0425
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -2.0418
AMOTL2 angiomotin like 2 -2.0386
MTPAP mitochondrial poly(A) polymerase -2.0369
ANKRD28 ankyrin repeat domain 28 -2.036
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled -2.0333
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 -2.0327
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -2.0323
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -2.0319
NRBP1 nuclear receptor binding protein 1 -2.0308
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 -2.03052
GTF2IRD1 GTF2I repeat domain containing 1 -2.0304
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -2.0302
ZNF208 zinc finger protein 208 -2.0302
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.0301
YBX3 Y box binding protein 3 -2.0281
ZNF154 zinc finger protein 154 -2.0271
LEF1 lymphoid enhancer-binding factor 1 -2.02627
RAB30 RAB30, member RAS oncogene family -2.026
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -2.0238
TRIT1 tRNA isopentenyltransferase 1 -2.0228
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 -2.0217
DNASE1L2 deoxyribonuclease I-like 2 -2.0213
AMH anti-Mullerian hormone -2.0212
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -2.02055
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.0203
TMEM80 transmembrane protein 80 -2.0197
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -2.0191
MBL2 mannose-binding lectin (protein C) 2, soluble -2.0185
PON1 paraoxonase 1 -2.01675
SART1 squamous cell carcinoma antigen recognized by T cells -2.0163
ACO1 aconitase 1, soluble -2.0141
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -2.0102
CLCA2 chloride channel accessory 2 -2.00975
CREB3L2 cAMP responsive element binding protein 3-like 2 -2.0071
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -2.0064
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.0063
ZFHX3 zinc finger homeobox 3 -2.0062
C1S complement component 1, s subcomponent -2.0044
TBC1D17 TBC1 domain family, member 17 -2.0038
CXCL9 chemokine (C-X-C motif) ligand 9 -2.0027
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -2.0023
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -2.0022
BPHL biphenyl hydrolase-like (serine hydrolase) -2.0004