CRCGN017_MCF10A.WT.HP_24H:I21 Gene Set
Genes
54 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SPAG4
|
sperm associated antigen 4
|
5.66755
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.96705
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
4.779
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.6507
|
|
USP7
|
ubiquitin specific peptidase 7 (herpes virus-associated)
|
3.60497
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.55903
|
|
HBB
|
hemoglobin, beta
|
3.45192
|
|
HBA1
|
hemoglobin, alpha 1
|
3.20496
|
|
WIF1
|
WNT inhibitory factor 1
|
3.1996
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.83082
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
2.78207
|
|
SESN1
|
sestrin 1
|
2.59115
|
|
TMEM186
|
transmembrane protein 186
|
2.5732
|
|
RPP40
|
ribonuclease P/MRP 40kDa subunit
|
2.5532
|
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
2.5402
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
2.45103
|
|
IL2RG
|
interleukin 2 receptor, gamma
|
2.3702
|
|
DHRS2
|
dehydrogenase/reductase (SDR family) member 2
|
2.2742
|
|
RNF43
|
ring finger protein 43
|
2.2515
|
|
ZBTB38
|
zinc finger and BTB domain containing 38
|
2.228
|
|
BBLN
|
bublin coiled coil protein
|
2.13648
|
|
LCMT1
|
leucine carboxyl methyltransferase 1
|
2.1258
|
|
NDUFA8
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
|
2.11775
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.0876
|
|
EIF1AY
|
eukaryotic translation initiation factor 1A, Y-linked
|
2.03038
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KRT14
|
keratin 14, type I
|
-6.43935
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-5.43435
|
|
SLC25A46
|
solute carrier family 25, member 46
|
-4.5576
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-3.93687
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
-3.4414
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.34245
|
|
MSN
|
moesin
|
-3.2658
|
|
XPO7
|
exportin 7
|
-3.15252
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.08173
|
|
CD81
|
CD81 molecule
|
-3.0579
|
|
FKBP4
|
FK506 binding protein 4, 59kDa
|
-2.89062
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.781
|
|
PRSS22
|
protease, serine, 22
|
-2.7078
|
|
CHORDC1
|
cysteine and histidine-rich domain (CHORD) containing 1
|
-2.52783
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-2.38135
|
|
WASHC4
|
WASH complex subunit 4
|
-2.36355
|
|
SECTM1
|
secreted and transmembrane 1
|
-2.33985
|
|
KDM5C
|
lysine (K)-specific demethylase 5C
|
-2.3009
|
|
HPSE2
|
heparanase 2 (inactive)
|
-2.24365
|
|
PGPEP1
|
pyroglutamyl-peptidase I
|
-2.2218
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-2.19447
|
|
CXCL6
|
chemokine (C-X-C motif) ligand 6
|
-2.1817
|
|
SERPINB4
|
serpin peptidase inhibitor, clade B (ovalbumin), member 4
|
-2.16442
|
|
SMC1A
|
structural maintenance of chromosomes 1A
|
-2.1501
|
|
LOC124905557
|
eukaryotic translation initiation factor 1A, X-chromosomal
|
-2.14105
|
|
PFN1
|
profilin 1
|
-2.1388
|
|
WDR91
|
WD repeat domain 91
|
-2.1252
|
|
PHACTR4
|
phosphatase and actin regulator 4
|
-2.10865
|
|
DAAM2
|
dishevelled associated activator of morphogenesis 2
|
-2.0179
|
