CRCGN017_MCF10A.WT.HP_24H:I22 Gene Set
Genes
35 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
5.01297
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
4.91765
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
4.19935
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
4.04835
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
3.54625
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
3.19038
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.744
|
|
SLC38A6
|
solute carrier family 38, member 6
|
2.37455
|
|
FBXO11
|
F-box protein 11
|
2.33457
|
|
MGAT4A
|
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
|
2.2188
|
|
BMP6
|
bone morphogenetic protein 6
|
2.0763
|
|
IGFBP3
|
insulin-like growth factor binding protein 3
|
2.05438
|
|
LAMP3
|
lysosomal-associated membrane protein 3
|
2.04585
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-5.27515
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-5.1186
|
|
TES
|
testin LIM domain protein
|
-4.79478
|
|
ETFB
|
electron-transfer-flavoprotein, beta polypeptide
|
-4.1536
|
|
KRT14
|
keratin 14, type I
|
-3.87595
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.7106
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
-3.63695
|
|
LYPLA1
|
lysophospholipase I
|
-3.63678
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.17325
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.1143
|
|
ARID4B
|
AT rich interactive domain 4B (RBP1-like)
|
-3.0017
|
|
ELAC2
|
elaC ribonuclease Z 2
|
-2.71055
|
|
WASHC4
|
WASH complex subunit 4
|
-2.49637
|
|
UBE4A
|
ubiquitination factor E4A
|
-2.48345
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.46555
|
|
ATP6V1H
|
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
|
-2.33795
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
-2.30253
|
|
NBPF10
|
neuroblastoma breakpoint family, member 10
|
-2.27595
|
|
TXNIP
|
thioredoxin interacting protein
|
-2.21385
|
|
EPS8
|
epidermal growth factor receptor pathway substrate 8
|
-2.2072
|
|
NBPF19
|
neuroblastoma breakpoint family, member 19
|
-2.1373
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.0734
|
