CRCGN017_MCF10A.WT.HP_24H:I23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyleugenol 33.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 5.33725
TLR4 toll-like receptor 4 5.07355
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.95795
PEX11A peroxisomal biogenesis factor 11 alpha 4.21415
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 4.0852
SESN1 sestrin 1 2.49
MANEA mannosidase, endo-alpha 2.2696
BRD7 bromodomain containing 7 2.11915
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.0417

decreased expression

Symbol Name Standardized Value
SLC35F2 solute carrier family 35, member F2 -5.3728
FASTKD5 FAST kinase domains 5 -4.9738
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.56425
SCYL3 SCY1-like 3 (S. cerevisiae) -3.3728
ACAA1 acetyl-CoA acyltransferase 1 -2.8611
FBXO21 F-box protein 21 -2.80155
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.45115
WASHC4 WASH complex subunit 4 -2.28132
REEP5 receptor accessory protein 5 -2.21482
ATXN2 ataxin 2 -2.12775
CLDN1 claudin 1 -2.07235