CRCGN017_MCF10A.WT.HP_24H:I24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyleugenol 11.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:I24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 4.38995
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.21805
CNRIP1 cannabinoid receptor interacting protein 1 3.35665
TBPL1 TBP-like 1 3.3308
UGDH UDP-glucose 6-dehydrogenase 3.28525
ACAA1 acetyl-CoA acyltransferase 1 3.14513
PDLIM1 PDZ and LIM domain 1 2.73585
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.46075
LUM lumican 2.41495
RHOG ras homolog family member G 2.18015
PRR7 proline rich 7 (synaptic) 2.16115
CADM1 cell adhesion molecule 1 2.10235

decreased expression

Symbol Name Standardized Value
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.99323
MSMO1 methylsterol monooxygenase 1 -4.89075
NUP85 nucleoporin 85kDa -4.7274
HMG20B high mobility group 20B -4.1106
COG7 component of oligomeric golgi complex 7 -3.9298
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.7727
CREG1 cellular repressor of E1A-stimulated genes 1 -3.51585
KCTD2 potassium channel tetramerization domain containing 2 -3.21202
RXYLT1 ribitol xylosyltransferase 1 -3.1666
SAP30BP SAP30 binding protein -2.9692
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -2.9506
ATP5PD ATP synthase peripheral stalk subunit d -2.5596
MRPS7 mitochondrial ribosomal protein S7 -2.43815
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -2.39205
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.29205
LCMT1 leucine carboxyl methyltransferase 1 -2.26155
PAIP1 poly(A) binding protein interacting protein 1 -2.19746
PALB2 partner and localizer of BRCA2 -2.17935
RNFT1-DT RNFT1 divergent transcript -2.0932
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -2.03038
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -2.02038
LIPG lipase, endothelial -2.00825
NLRX1 NLR family member X1 -2.0003