| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-chloro-p-phenylenediamine sulfate 11.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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75 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:J03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.95969 |
| COMP | cartilage oligomeric matrix protein | 4.28197 |
| MAMLD1 | mastermind-like domain containing 1 | 4.1688 |
| UGDH | UDP-glucose 6-dehydrogenase | 3.67471 |
| NBEA | neurobeachin | 3.02822 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.98818 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 2.84742 |
| TBX2 | T-box 2 | 2.84162 |
| RFPL2 | ret finger protein-like 2 | 2.66272 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 2.59837 |
| FCHO1 | FCH domain only 1 | 2.58977 |
| FBXO11 | F-box protein 11 | 2.5332 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.53114 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.51547 |
| SOCS5 | suppressor of cytokine signaling 5 | 2.43415 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | 2.34322 |
| EPHB2 | EPH receptor B2 | 2.24236 |
| IL6 | interleukin 6 | 2.22667 |
| MSH2 | mutS homolog 2 | 2.22262 |
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) | 2.22212 |
| REG1B | regenerating islet-derived 1 beta | 2.212 |
| RFPL3 | ret finger protein-like 3 | 2.17747 |
| PLAC1 | placenta-specific 1 | 2.15035 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 2.14873 |
| CLDN3 | claudin 3 | 2.12825 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 | 2.12799 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.10765 |
| ZNF85 | zinc finger protein 85 | 2.08727 |
| MINDY3 | MINDY lysine 48 deubiquitinase 3 | 2.07944 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | 2.07319 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 2.05746 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 | 2.05284 |
| FGF7 | fibroblast growth factor 7 | 2.04754 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2.0468 |
| TAGLN3 | transgelin 3 | 2.04154 |
| GPATCH8 | G patch domain containing 8 | 2.03974 |
| PYGM | phosphorylase, glycogen, muscle | 2.03536 |
| MRPL12 | mitochondrial ribosomal protein L12 | 2.03361 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 2.03212 |
| FZD7 | frizzled class receptor 7 | 2.01573 |
| SSUH2 | ssu-2 homolog (C. elegans) | 2.00494 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MRPS16 | mitochondrial ribosomal protein S16 | -5.90571 |
| TNIP1 | TNFAIP3 interacting protein 1 | -5.76491 |
| SLC35F2 | solute carrier family 35, member F2 | -5.16132 |
| ACOT9 | acyl-CoA thioesterase 9 | -4.7143 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -4.59453 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.43065 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.03718 |
| CD81 | CD81 molecule | -3.78013 |
| KRT14 | keratin 14, type I | -3.09276 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.89361 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | -2.82568 |
| MSN | moesin | -2.71022 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.67529 |
| CD58 | CD58 molecule | -2.63651 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -2.55238 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -2.5397 |
| OXCT1 | 3-oxoacid CoA transferase 1 | -2.49864 |
| COPS7A | COP9 signalosome subunit 7A | -2.49368 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -2.45265 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -2.28288 |
| CHMP2A | charged multivesicular body protein 2A | -2.27428 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -2.2725 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -2.20121 |
| PRR13 | proline rich 13 | -2.18911 |
| GIPC1 | GIPC PDZ domain containing family, member 1 | -2.18647 |
| GAA | glucosidase, alpha; acid | -2.14914 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | -2.14748 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.13204 |
| ZNF672 | zinc finger protein 672 | -2.12856 |
| TLCD3A | TLC domain containing 3A | -2.12672 |
| APOO | apolipoprotein O | -2.07586 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -2.05098 |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 | -2.04044 |
| COX7C | cytochrome c oxidase subunit VIIc | -2.00446 |