CRCGN017_MCF10A.WT.HP_24H:J06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-nitro-o-phenylenediamine 11.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:J06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 5.71299
TXNRD1 thioredoxin reductase 1 4.83152
IDE insulin-degrading enzyme 4.19653
WFS1 Wolfram syndrome 1 (wolframin) 4.049
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.88895
HBB hemoglobin, beta 3.88446
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.19696
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 3.17688
HMOX1 heme oxygenase 1 3.11857
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 2.46929
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.32966
CNRIP1 cannabinoid receptor interacting protein 1 2.30385
ETFB electron-transfer-flavoprotein, beta polypeptide 2.04751

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -6.86973
JMJD6 jumonji domain containing 6 -3.44888
CTNND1 catenin (cadherin-associated protein), delta 1 -2.63335
SCYL3 SCY1-like 3 (S. cerevisiae) -2.47813
MXRA7 matrix-remodelling associated 7 -2.35497
KRT20 keratin 20, type I -2.12993
TES testin LIM domain protein -2.10928