CRCGN017_MCF10A.WT.HP_24H:J11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description caprolactam 33.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:J11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 5.44205
PRKCH protein kinase C, eta 4.20323
CDCA4 cell division cycle associated 4 4.00765
GATA3 GATA binding protein 3 3.86297
ACAA1 acetyl-CoA acyltransferase 1 3.2064
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.0048
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.89325
BLTP2 bridge-like lipid transfer protein family member 2 2.87343
INTS3 integrator complex subunit 3 2.78275
CASZ1 castor zinc finger 1 2.40365
OLFML2B olfactomedin-like 2B 2.26185
POLE polymerase (DNA directed), epsilon, catalytic subunit 2.2362
ATP13A1 ATPase type 13A1 2.21735
CNRIP1 cannabinoid receptor interacting protein 1 2.1678
ZMIZ1 zinc finger, MIZ-type containing 1 2.1258
EFNA1 ephrin-A1 2.03695

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.88395
CD81 CD81 molecule -4.63845
GDF15 growth differentiation factor 15 -4.419
COPS7A COP9 signalosome subunit 7A -4.25895
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.9965
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.8771
S100A4 S100 calcium binding protein A4 -2.58435
BASP1 brain abundant, membrane attached signal protein 1 -2.5404
DUSP6 dual specificity phosphatase 6 -2.4079
DIPK1A divergent protein kinase domain 1A -2.22787
TRAF5 TNF receptor-associated factor 5 -2.18165
LPXN leupaxin -2.1044
P3H3 prolyl 3-hydroxylase 3 -2.0906
BCAS4 breast carcinoma amplified sequence 4 -2.09
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.0662